Catalog No.
YHG33101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys148-Lys312
Predicted molecular weight
20.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12904
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AIMP1, Endothelial monocyte-activating polypeptide II, EMAP-II, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP-2, SCYE1, EMAP2, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1
Response to anti-angiogenic therapy is affected by AIMP protein family activity in glioblastoma and lower-grade gliomas., PMID:40161601
Identification of an immune-related gene panel for the diagnosis of pulmonary arterial hypertension using bioinformatics and machine learning., PMID:39616855
Assembly of the Human Multi-tRNA Synthetase Complex Through Leucine Zipper Motifs., PMID:39542129
Machine learning accelerates the discovery of epitope-based dual-bioactive peptides against skin infections., PMID:39486466
Anti-aminoacyl-tRNA synthetase-interacting multifunctional protein-1 antibody improves airway inflammation in mice with house dust mite induced asthma., PMID:39262899
A Novel Homozygous Splice Site Variant in AIMP1 Gene Causing Hypomyelinating Leukodystrophy: Case Report and Review of the Literature., PMID:36652953
Secreted aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1) is a promising predictor for the severity of acute AQP4-IgG positive neuromyelitis optica spectrum disorder., PMID:36623394
Aminoacyl transfer ribonucleic acid synthetase complex-interacting multifunctional protein 1 induces microglial activation and M1 polarization via the mitogen-activated protein kinase/nuclear factor-kappa B signaling pathway., PMID:36159396
Involvement of inflammatory cytokines and epigenetic modification of the mtTFA complex in T-helper cells of patients' suffering from non-small cell lung cancer and chronic obstructive pulmonary disease., PMID:36099831
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation., PMID:36042007
Age-associated changes in gene expression in the anterior pituitary glands of female Japanese black cattle., PMID:35838775
T helper cell-mediated epitranscriptomic regulation via m6A RNA methylation bridges link between coronary artery disease and invasive ductal carcinoma., PMID:35776197
NeoPep S: A New Generation of AIMP1-derived Peptide (AdP) Effects on Wound Healing In Vivo., PMID:35478120
Clinical powers of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) for head-neck squamous cell carcinoma., PMID:35068446
Systematic expression profiling of neuropathy-related aminoacyl-tRNA synthetases in zebrafish during development., PMID:34872004
Atlas of receptor genes expressed by the bovine morula and corresponding ligand-related genes expressed by uterine endometrium., PMID:34596291
Loss of GATA4 C-Terminus by p.S335X Mutation Modulates Coronary Artery Vascular Smooth Muscle Cell Phenotype., PMID:34545275
Towards Tumor Targeting via Invasive Assay Using Magnetospirillum magneticum., PMID:34367097
R-loop modulated epigenetic regulation in T helper cells mechanistically associates coronary artery disease and non-small cell lung cancer., PMID:34343853
Peripheral nerves are involved in hypomyelinating leukodystrophy-3 caused by a homozygous AIMP1 variant., PMID:33402283
Transient Changes of Metabolism at the Pronuclear Stage in Mice Influences Skeletal Muscle Phenotype in Adulthood., PMID:33003470
Characteristics of Atmospheric Fine Particulate Matter (PM 2.5) Induced Differentially Expressed Proteins Determined by Proteomics and Bioinformatics Analyses., PMID:32933610
Roles of aminoacyl-tRNA synthetase-interacting multi-functional proteins in physiology and cancer., PMID:32709848
Influence of aminoacyl-tRNA synthetase complex-interacting multifunctional protein 1 on epithelial differentiation and organization during lung development., PMID:32579851
Rare homozygous nonsense variant in AIMP1 causing Early Onset Epileptic Encephalopathy with Burst Suppression (EOEE-BS)., PMID:32531460
Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen., PMID:32384815
Investigation of the gene co-expression network and hub genes associated with acute mountain sickness., PMID:32299499
MHC class I and II peptide homology regulates the cellular immune response., PMID:32298026
Saliva proteomics from children with caries at different severity stages., PMID:32285988
Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein., PMID:32038044
Stabilization of AIMP1/p43 and EMAP II recombinant proteins in the complexes with polysaccharide dextran-70., PMID:32016851
The Role of the AIMP1 Pathway in Diabetic Retinopathy: AIMP1-Targeted Intervention Study in Diabetic Retinopathy., PMID:31962335
The Genetic Landscape of Epilepsy of Infancy with Migrating Focal Seizures., PMID:31618474
The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex., PMID:31576228
Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase., PMID:31473157
Atializumab, a humanized anti-aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1) antibody significantly improves nephritis in (NZB/NZW) F1 mice., PMID:31394431
Newly acquired N-terminal extension targets threonyl-tRNA synthetase-like protein into the multiple tRNA synthetase complex., PMID:31287872
Mass Spectrometric Analysis Identifies AIMP1 and LTA4H as FSCN1-Binding Proteins in Laryngeal Squamous Cell Carcinoma., PMID:31287215
Serum Aminoacyl-tRNA Synthetase-Interacting Multifunctional Protein-1 Can Predict Severe Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Pilot Monocentric Study., PMID:31236412
Functional Fragments of AIMP1-Derived Peptide (AdP) and Optimized Hydrosol for Their Topical Deposition by Box-Behnken Design., PMID:31121831
AIMP1 regulates TCR signaling and induces differentiation of regulatory T cells by interfering with lipid raft association., PMID:31084930
Fluorescence-Based Analysis of Noncanonical Functions of Aminoacyl-tRNA Synthetase-Interacting Multifunctional Proteins (AIMPs) in Peripheral Nerves., PMID:30939730
Pathogenic variants in AIMP1 cause pontocerebellar hypoplasia., PMID:30924036
AIMP1 Mutation Long-Term Follow-Up, With Decreased Brain N-Acetylaspartic Acid and Secondary Mitochondrial Abnormalities., PMID:30828585
Biallelic Loss-of-Function Variants in AIMP1 Cause a Rare Neurodegenerative Disease., PMID:30486714
Novel Homozygous Mutation of the AIMP1 Gene: A Milder Neuroimaging Phenotype With Preservation of the Deep White Matter., PMID:30477741
Dual functional bioactive-peptide, AIMP1-derived peptide (AdP), for anti-aging., PMID:29921010
Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 simultaneously binds Glutamyl-Prolyl-tRNA synthetase and scaffold protein aminoacyl tRNA synthetase complex interacting multifunctional protein 3 of the multi-tRNA synthetase complex., PMID:29679766
Serum aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1), a novel disease activity predictive biomarker of systemic lupus erythematosus., PMID:29352840
Homozygosity for a nonsense variant in AIMP2 is associated with a progressive neurodevelopmental disorder with microcephaly, seizures, and spastic quadriparesis., PMID:29215095
For research use only. Not for human or drug use.
