Catalog No.
YHG30301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln218-Arg471
Predicted molecular weight
30.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12834
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cell division cycle protein 20 homolog, p55CDC, CDC20
Blocking mutant IDH1 phosphorylation triggers APC/C CDH1-dependent ubiquitination in mitotic cells., PMID:40513618
Mixture of common and uncommon pathways and genes regulating primary and secondary immunoglobulin M responses in chickens., PMID:40499239
A novel programmed cell death signature predicts clinical outcomes in clear cell renal cell carcinoma and identifies PLK1 as a therapeutic target., PMID:40488834
Integrative in silico analysis of per- and polyfluorinated alkyl substances (PFAS)-associated molecular alterations in human cancers: a multi-cancer framework for predicting toxicogenomic disruption., PMID:40474796
Linear ubiquitination of p31comet by HOIP couples cytokine response with mitotic regulation., PMID:40462232
Omaveloxolone Suppresses Cell Growth and Causes Cell Cycle Arrest by Downregulating CDC20 Expression in Glioblastoma Cells Both In Vitro and In Vivo., PMID:40439120
Mutual regulation between cell cycle and transcription termination factor TTF2., PMID:40410652
Identification of metabolic reprogramming-related key genes in hepatocellular carcinoma after transcatheter arterial chemoembolization treatment., PMID:40404896
hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan., PMID:40371663
Integrative bioinformatic analysis identifies differentially expressed gene targets as potential biomarkers for anaplastic thyroid cancer., PMID:40350533
A bioinformatics exploration of lung adenocarcinoma identifies hub genes with prognostic significance: from data to discovery., PMID:40320470
Ubiquitin-proteasome Pathway-linked Gene Signatures as Prognostic Indicators in Prostate Cancer., PMID:40295064
Identification of the oncogenic role of centromere protein M in non-small cell lung cancer via CDC20/MYBL2/Wnt signaling pathways., PMID:40285932
Thyroid hormone receptor interacting protein 13 is associated with prognosis and immunotherapy efficacy in human cancers: a pan-cancer analysis., PMID:40253660
ANAPHASE-PROMOTING COMPLEX/CYCLOSOME coactivators maintain AURORA 1 kinase homeostasis during meiotic chromosome segregation., PMID:40244922
Transcriptome Profiling and Viral-Human Interactome Insights Into HBV-Driven Oncogenic Alterations in Hepatocellular Carcinoma., PMID:40243270
Non-canonical HIPPO-MST1/2 promotes hyper-proliferation of pulmonary vascular cells through CDC20., PMID:40236147
Clinical Outcomes and Genomic Alterations in Gleason Score 10 Prostate Cancer., PMID:40227503
Decoding Colorectal Cancer: Key Genes and Pathways in the Chinese Population Revealed., PMID:40183269
Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma., PMID:40180891
Bioinformatics screened of biomarkers for the prognosis of hepatocellular carcinoma., PMID:40179431
Identification and validation of CDC20 and ITCH as ubiquitination related biomarker in idiopathic pulmonary fibrosis., PMID:40170095
Studies on the regulation of E3 ubiquitin ligase APC3 and its interacting proteins on the tetraspore formation and release in Gracilariopsis lemaneiformis (Rhodophyta)., PMID:40169068
Discovering potential therapeutic targets in glioblastoma multiforme using a multi-omics approach., PMID:40168776
Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20., PMID:40143766
C-Terminal Hsp90 Inhibitors Overcome MEK and BRAF Inhibitor Resistance in Melanoma., PMID:40135438
Prognostic Value of Centrosome Replication-Related Genes in Prostate Cancer Based on Transcriptomic and Mendelian Randomization., PMID:40099722
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
NSUN4 Facilitates the Activity of Oncogenic Protein CDC20 to Promote NSCLC Development by Mediating m5C Modification of CDC20 mRNA., PMID:40051202
CDC20 protects the heart from doxorubicin-induced cardiotoxicity by modulating CCDC69 degradation., PMID:40045239
Plant cell-cycle regulators control the nuclear environment for viral pathogenesis., PMID:40043702
Design, synthesis and optimization of Apcin analogues as Cdc20 inhibitors for triple-negative breast cancer therapy., PMID:40020424
CENPF as a prognostic marker of glioma: unraveling the molecular mechanisms., PMID:40019588
Correction for Deng et al., The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling., PMID:40014562
Small Molecules Identified by an In Silico Docking Screen Targeting Anaphase-Promoting Complex/Cyclosome Subunit 1 (APC1) Potentiate Paclitaxel-Induced Breast Cancer Cell Death., PMID:40005207
Bioinformatics analysis identifies dysregulation of miR-548F-3p and its hub gene in triple-negative breast cancer., PMID:39968094
Identification of Novel lncRNAs Related to Colorectal Cancer Through Bioinformatics Analysis., PMID:39949372
Exploration of telomere-related biomarkers for lung adenocarcinoma and targeted drug prediction., PMID:39928198
Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma., PMID:39908244
Therapeutic target genes and regulatory networks of gallic acid in cervical cancer., PMID:39902297
Biallelic mutations in CDC20 cause female infertility due to oocyte maturation abnormality., PMID:39862142
High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors., PMID:39838194
The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation., PMID:39821696
Loss of HNRNPK During Cell Senescence Linked to Reduced Production of CDC20., PMID:39804141
Genomic and Transcriptomic Profiling of Digital Papillary Adenocarcinomas Reveals Alterations in Matrix Remodeling and Metabolic Genes., PMID:39757862
Identification and validation of KIF20A for predicting prognosis and treatment outcomes in patients with breast cancer., PMID:39733078
Protective Role of TAOK1-CDC20 Axis in Atherosclerosis: Modulation of Endothelial Apoptosis and Senescence., PMID:39726311
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for therapeutic potential., PMID:39715832
Mechanism underlying CDC20 affecting epithelial ovarian cancer biological behavior by regulating BAG6 ubiquitination., PMID:39710091
CDC20-Mediated Selective Autophagy Degradation of PBRM1 Affects Immunotherapy for Renal Cell Carcinoma., PMID:39656940
For research use only. Not for human or drug use.
