Catalog No.
YHG29201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp101-Thr270
Predicted molecular weight
21.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12797
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aspartyl/asparaginyl beta-hydroxylase, ASP beta-hydroxylase, Aspartate beta-hydroxylase, ASPH, BAH, Peptide-aspartate beta-dioxygenase
Modified screening of MYC promotor region elements using the CRISPR library in ovarian cancer., PMID:40176181
Aspartate beta-hydroxylase is a prognostic factor in gallbladder cancer with the function of promoting tumorigenesis and chemoresistance., PMID:40110547
Genetic landscape and ocular biometric correlations in microspherophakia: insights from a comprehensive patient cohort., PMID:40025527
Calcium electroporation induces stress response through upregulation of HSP27, HSP70, aspartate β-hydroxylase, and CD133 in human colon cancer cells., PMID:39980072
Integrative Analysis of Radiation-Induced Senescence-Associated Secretory Phenotype Factors in Kidney Cancer Progression., PMID:39858632
Proximity Labeling-Based Identification of MGAT3 Substrates and Revelation of the Tumor-Suppressive Role of Bisecting GlcNAc in Breast Cancer via GLA Degradation., PMID:39851531
Mechanisms of METTL14-Mediated m6A Modification in Promoting Iron Overload-Induced Lipid Peroxidative Damage in Vascular Endothelial Cells to Aggravate Atherosclerosis., PMID:39588760
Methods for production and assaying catalysis of isolated recombinant human aspartate/asparagine-β-hydroxylase., PMID:39300654
Molecular Responses of Anti-VEGF Therapy in Neovascular Age-Related Macular Degeneration: Integrative Insights From Multi-Omics and Clinical Imaging., PMID:39140961
Identification of core genes in intervertebral disc degeneration using bioinformatics and machine learning algorithms., PMID:39050860
Circ_0005699 Expedites ox-LDL-Triggered Endothelial Cell Injury via Targeting miR-384/ASPH Axis., PMID:38976139
Aspartate-β-hydroxylase and hypoxia marker expression in head and neck carcinomas: implications for HPV-associated tumors., PMID:38858774
Effects of Clinical Mutations in the Second Coordination Sphere and Remote Regions on the Catalytic Mechanism of Non-Heme Fe(II)/2-Oxoglutarate-Dependent Aspartyl Hydroxylase AspH., PMID:38839574
Genotype-phenotype profile of global ASPH-associated ectopia lentis and clinical findings from a Chinese cohort., PMID:38788814
Aspartate β-Hydroxylase Is Upregulated in Head and Neck Squamous Cell Carcinoma and Regulates Invasiveness in Cancer Cell Models., PMID:38732216
Vitamin K-dependent carboxylation in β-cells and diabetes., PMID:38429160
Aspartate β-hydroxylase Regulates Expression of Ly6 Genes., PMID:38356711
Association between dietary soy prevention of fetal alcohol spectrum disorder and normalization of placental insulin and insulin-like growth factor signaling networks and downstream effector molecule expression., PMID:39925675
Deep topographic proteomics of a human brain tumour., PMID:38001067
Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA., PMID:37848499
Topology and adenocarcinoma cell localization dataset on the labyrinthin diapeutic biomarker., PMID:37415228
Identification of critical genes associated with lead exposure based on in silico analysis., PMID:37178329
Traboulsi syndrome without features of Marfan syndrome caused by a novel homozygous ASPH variant associated with a heterozygous FBN1 variant., PMID:37133842
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway., PMID:37132101
The Role of Genetic Testing in Children Requiring Surgery for Ectopia Lentis., PMID:37107549
Aspartate β-Hydroxylase Serves as a Prognostic Biomarker for Neoadjuvant Chemotherapy in Gastric Cancer., PMID:36982561
Overexpression of ASPH protein predicts poor outcomes in retroperitoneal liposarcoma patients., PMID:36897757
New panel of biomarkers to discriminate between amelanotic and melanotic metastatic melanoma., PMID:36776379
Differential rescue effects of choline chloride and soy isolate on metabolic dysfunction in immature central nervous system neurons: Relevance to fetal alcohol spectrum disorder., PMID:39601020
Production of a Novel Multi-Epitope Peptide Vaccine against Hepatocellular Carcinoma., PMID:36380977
Anti-inflammatory action of ark shell (Scapharca subcrenata) protein hydrolysate in LPS-stimulated RAW264.7 murine macrophages., PMID:36309949
Modification of Regulatory T Cell Epitopes Promotes Effector T Cell Responses to Aspartyl/Asparaginyl β-Hydroxylase., PMID:36293298
Identification of critical genes associated with radiotherapy resistance in cervical cancer by bioinformatics., PMID:35965520
Traboulsi syndrome caused by mutations in ASPH: An autosomal recessive disorder with overlapping features of Marfan syndrome., PMID:35918038
The prognostic value of aspartate beta-hydroxylase in early breast cancer., PMID:35726161
Combined proteomic and biochemical analyses redefine the consensus sequence requirement for epidermal growth factor-like domain hydroxylation., PMID:35700824
Variants in ASPH cause exertional heat illness and are associated with malignant hyperthermia susceptibility., PMID:35697689
Dietary Soy Prevents Alcohol-Mediated Neurocognitive Dysfunction and Associated Impairments in Brain Insulin Pathway Signaling in an Adolescent Rat Model., PMID:35625605
Whole exome sequencing of known eye genes reveals genetic causes for high myopia., PMID:35567543
Adaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade., PMID:35392977
Labyrinthin: A distinct pan-adenocarcinoma diagnostic and immunotherapeutic tumor specific antigen., PMID:35252607
Aspartate β-Hydroxylase (ASPH) Expression in Acute Myeloid Leukemia: A Potential Novel Therapeutic Target., PMID:35004304
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma., PMID:34996491
Amaranth selective hydrolyzed protein influence on sourdough fermentation and wheat bread quality., PMID:34925798
Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer., PMID:34659881
Astragalus membranaceus polysaccharides modulate growth, hemato-biochemical indices, hepatic antioxidants, and expression of HSP70 and apoptosis-related genes in Oreochromis niloticus exposed to sub-lethal thallium toxicity., PMID:34509627
Overexpression of Human Aspartyl (Asparaginyl) β-hydroxylase in NSCLC: Its Diagnostic Value by Means of Exosomes of Bronchoalveolar Lavage., PMID:34433181
D-2-hydroxyglutarate dehydrogenase in breast carcinoma as a potent prognostic marker associated with proliferation., PMID:34296423
Human aspartyl (asparaginyl) hydroxylase. A multifaceted enzyme with broad intra- and extra-cellular activity., PMID:34283245
Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture., PMID:34249415
For research use only. Not for human or drug use.
