Catalog No.
YHG26601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg63-Ala313
Predicted molecular weight
30.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q10588
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, Bone marrow stromal antigen 1, BST-1, ADP-ribosyl cyclase 2, CD157, Cyclic ADP-ribose hydrolase 2, BST1, cADPr hydrolase 2
Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity., PMID:40407837
Oral Supplementation of L-Carnosine Attenuates Acute-Stress-Induced Corticosterone Release and Mitigates Anxiety in CD157 Knockout Mice., PMID:39275136
Discovery of Transcription Factors Involved in the Maintenance of Resident Vascular Endothelial Stem Cell Properties., PMID:38247234
Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice., PMID:37215105
Linking autism spectrum disorders and parkinsonism: clinical and genetic association., PMID:36738194
Bone marrow stromal cell antigen-1 (CD157) regulated by sphingosine kinase 2 mediates kidney fibrosis., PMID:36267620
CD38-Cyclic ADP-Ribose Signal System in Physiology, Biochemistry, and Pathophysiology., PMID:35457121
Identification of CD157-Positive Vascular Endothelial Stem Cells in Mouse Retinal and Choroidal Vessels: Fluorescence-Activated Cell Sorting Analysis., PMID:35394492
A new strategy to count and sort neutrophil-derived extracellular vesicles: Validation in infectious disorders., PMID:35362257
Synthesis of genetic association studies on autism spectrum disorders using a genetic model-free approach., PMID:35353796
CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1., PMID:34707185
Profound inhibition of CD73-dependent formation of anti-inflammatory adenosine in B cells of SLE patients., PMID:34666225
Blending oxytocin and dopamine with everyday creativity., PMID:34376746
CD157 in bone marrow mesenchymal stem cells mediates mitochondrial production and transfer to improve neuronal apoptosis and functional recovery after spinal cord injury., PMID:34001228
Enzymology of extracellular NAD metabolism., PMID:33755743
[Features of the in vitro expression profile of hippocampal neurogenic niche cells during optogenetic stimulation]., PMID:33645520
NAD+ and cardiovascular diseases., PMID:33485900
Benzo[a]pyrene induces fibrotic changes and impairs differentiation in lung stem cells., PMID:33429317
Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging., PMID:33326496
CD157 and Brain Immune System in (Patho)physiological Conditions: Focus on Brain Plasticity., PMID:33304350
Utility of FLAER and CD157 in a five-color single-tube high sensitivity assay, for diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)-A standalone flow cytometry laboratory experience., PMID:33058446
Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder., PMID:32572044
A Novel Role of CD38 and Oxytocin as Tandem Molecular Moderators of Human Social Behavior., PMID:32360414
Circulating Leukocyte Alterations and the Development/Progression of Diabetic Retinopathy in Type 1 Diabetic Patients - A Pilot Study., PMID:31997663
Roles of CD38 in the Immune Response to Infection., PMID:31963337
CD38, CD157, and RAGE as Molecular Determinants for Social Behavior., PMID:31881755
The Roles of CD38 and CD157 in the Solid Tumor Microenvironment and Cancer Immunotherapy., PMID:31861847
CD157: From Myeloid Cell Differentiation Marker to Therapeutic Target in Acute Myeloid Leukemia., PMID:31817547
Ectonucleotidases in Blood Malignancies: A Tale of Surface Markers and Therapeutic Targets., PMID:31636635
Diagnosis of paroxysmal nocturnal hemoglobinuria with flowcytometry panels including CD157: Data from the real world., PMID:31571381
CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production., PMID:31455656
A phylogenetic view of the leukocyte ectonucleotidases., PMID:29958894
CD157: From immunoregulatory protein to potential therapeutic target., PMID:29936181
Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma., PMID:29854315
High sensitivity 8-color flow cytometry assay for paroxysmal nocturnal hemoglobinuria granulocyte and monocyte detections., PMID:29599976
Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells., PMID:29549115
CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties., PMID:29429943
The Monoclonal Anti-CD157 Antibody Clone SY11B5, Used for High Sensitivity Detection of PNH Clones on WBCs, Fails to Detect a Common Polymorphic Variant Encoded by BST-1., PMID:29360268
A study of single nucleotide polymorphisms in CD157, AIM2 and JARID2 genes in Han Chinese children with autism spectrum disorder., PMID:29216786
Human canonical CD157/Bst1 is an alternatively spliced isoform masking a previously unidentified primate-specific exon included in a novel transcript., PMID:29162908
Targeting NAD+ degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty., PMID:28847709
Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration., PMID:28548540
CD73 on T Cells Orchestrates Cardiac Wound Healing After Myocardial Infarction by Purinergic Metabolic Reprogramming., PMID:28432149
Targeting CD157 in AML using a novel, Fc-engineered antibody construct., PMID:28415689
An immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator., PMID:28340569
ADP ribosyl-cyclases (CD38/CD157), social skills and friendship., PMID:28212520
Epigenetic-mediated immune suppression of positive co-stimulatory molecules in chemoresistant ovarian cancer cells., PMID:28074529
Performance Characteristics of a Non-Fluorescent Aerolysin-Based Paroxysmal Nocturnal Hemoglobinuria (PNH) Assay for Simultaneous Evaluation of PNH Neutrophils and PNH Monocytes by Flow Cytometry, Following Published PNH Guidelines., PMID:27294344
Combination of CD157 and FLAER to Detect Peripheral Blood Eosinophils by Multiparameter Flow Cytometry., PMID:26490516
CD56brightCD16- NK Cells Produce Adenosine through a CD38-Mediated Pathway and Act as Regulatory Cells Inhibiting Autologous CD4+ T Cell Proliferation., PMID:26091716
For research use only. Not for human or drug use.
