Catalog No.
YHG24401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser509
Predicted molecular weight
57.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q0VDF9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSP70L1, Heat shock 70 kDa protein 14, HSPA14, Heat shock protein HSP60, HSP70-like protein 1, HSP60
Identification and characterization of hsp70 gene family in Acrossocheilus fasciatus based on genome and full-length transcripts., PMID:40106884
Effects of in vitro cytochalasin D and hypoxia on mitochondrial energetics and biogenesis, cell signal status and actin/tubulin/Hsp/MMP entity in air-breathing fish heart., PMID:39864717
The role of HSPA14 in breast cancer: implications for tumorigenesis, immune response modulation, and personalized therapies., PMID:39828281
Genome-Wide Identification, Molecular Characterization, and Expression Analysis of the HSP70 and HSP90 Gene Families in Thamnaconus septentrionalis., PMID:38891896
Expression of HSPA14 in patients with acute HIV-1 infection and its effect on HIV-1 replication., PMID:36845091
A Comprehensive Stemness Gene Expression Analysis Signifies the Role of ABC Transporters and Molecular Chaperons in Determining the Fate of Human Neural Precursor Cells., PMID:35864646
Fatigue and expression of heat-shock protein genes in plaque psoriasis., PMID:34921435
Upregulation of HSPA1A/HSPA1B/HSPA7 and Downregulation of HSPA9 Were Related to Poor Survival in Colon Cancer., PMID:34765552
The expression profiles and prognostic values of HSP70s in hepatocellular carcinoma., PMID:34059060
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members., PMID:33860124
Different responses of apoptotic, inflammatory and heat shock protein gene expression to a single bout of high-intensity interval exercise between physically active and inactive men., PMID:33439763
Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors., PMID:33225964
Pathogen-associated molecular patterns and extracellular Hsp70 interplay in NLRP3 inflammasome activation in monocytic and bronchial epithelial cellular models of COPD exacerbations., PMID:33022793
Telomerase promotes formation of a telomere protective complex in cancer cells., PMID:31616780
XPO1 is a critical player for bortezomib resistance in multiple myeloma: A quantitative proteomic approach., PMID:31465861
Amino acid transporter SLC6A14 depends on heat shock protein HSP90 in trafficking to the cell surface., PMID:31326539
Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapy - potential markers for predicting breast cancer recurrence?, PMID:31077235
Advances in the pathogenesis representing definite outcomes in chronic urticaria., PMID:30676342
Intracellular HSP70L1 inhibits human dendritic cell maturation by promoting suppressive H3K27me3 and H2AK119Ub1 histone modifications., PMID:30635648
δ-Tocotrienol feeding modulates gene expression of EIF2, mTOR, protein ubiquitination through multiple-signaling pathways in chronic hepatitis C patients., PMID:30031388
Identification of over expressed proteins in oral submucous fibrosis by proteomic analysis., PMID:28980718
CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis., PMID:28878328
Role of Elsholtzia communis in counteracting stress by modulating expression of hspa14, C/EBP homologous protein, nuclear factor (erythroid-derived 2)-like-2 factor, Caspase-3, and brain-derived neurotrophic factor in rat hippocampus., PMID:28706332
The effect of kinetic heat shock on bovine oocyte maturation and subsequent gene expression of targeted genes., PMID:28592345
Association of the expression level of the neurodegeneration-related proteins with the risk of development and progression of primary open-angle glaucoma., PMID:28556468
Plasmodium Hsp40 and human Hsp70: A potential cochaperone-chaperone complex., PMID:28322872
Molecular cloning and expression analysis of five heat shock protein 70 (HSP70) family members in Lateolabrax maculatus with Vibrio harveyi infection., PMID:27908666
Protein-protein interaction network of celiac disease., PMID:27895852
Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ERα) and Biochemical Characterization of the ERα-Hsp70 Interaction., PMID:27483141
HSP70L1-mediated intracellular priming of dendritic cell vaccination induces more potent CTL response against cancer., PMID:27345726
Variation in Hsp70-1A Expression Contributes to Skin Color Diversity., PMID:27094592
Gene expression, oocyte nuclear maturation and developmental competence of bovine oocytes and embryos produced after in vivo and in vitro heat shock., PMID:27019120
Altered Expression of High Molecular Weight Heat Shock Proteins after OCT4B1 Suppression in Human Tumor Cell Lines., PMID:26862520
Leukocyte integrin α4β7 associates with heat shock protein 70., PMID:26260051
Analysis of the expression and polymorphism of APOE, HSP, BDNF, and GRIN2B genes associated with the neurodegeneration process in the pathogenesis of primary open angle glaucoma., PMID:25893192
Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular carcinoma., PMID:25798051
A small molecule inhibitor of ATPase activity of HSP70 induces apoptosis and has antitumor activities., PMID:25772468
The effect of vitrification of immature bovine oocytes to the subsequent in vitro development and gene expression., PMID:25424305
Gene expression of Hsps in normal and abnormal embryonic development of mouse hindlimbs., PMID:25352652
A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter., PMID:25202009
Proteomic and functional analyses demonstrate the involvement of oxidative stress in the anticancer activities of oridonin in HepG2 cells., PMID:24627081
Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients., PMID:24328534
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells., PMID:23416714
Attenuation of contact hypersensitivity by cell-permeable heat shock protein 70 in BALB/c mouse model., PMID:23171464
Gene expression of Hsp70, Hsp90 and Hsp110 families in normal palate and cleft palate during mouse embryogenesis., PMID:22585935
Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity., PMID:22234866
Gene expression of Hsp70, Hsp90, and Hsp110 families in normal and abnormal embryonic development of mouse forelimbs., PMID:22168448
Efficient induction of a Her2-specific anti-tumor response by dendritic cells pulsed with a Hsp70L1-Her2(341-456) fusion protein., PMID:21785448
Toll-like receptor 4 (TLR4) is essential for Hsp70-like protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response., PMID:21730052
Heat shocks enhance procollagen type I and III expression in fibroblasts in ex vivo human skin., PMID:21251083
For research use only. Not for human or drug use.
