Catalog No.
YHG20801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val112
Predicted molecular weight
14.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q09666
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neuroblast differentiation-associated protein AHNAK, PM227, AHNAK, Desmoyokin
A benchtop bioreactor to impart coarctation-induced deformation and assess mechanisms of endothelial dysfunction., PMID:40501964
AHNAK2 confers 5-fluorouracil resistance in colorectal cancer via activation of the AKT/GSK-3β signaling axis., PMID:40382757
Genomic mutation and Clinicopathological features of KRAS wild-type tumors in Chinese cohort with pancreatic adenocarcinoma., PMID:40274200
Comparative Analysis of Primary Sarcopenia and End-Stage Renal Disease-Related Muscle Wasting Using Multi-Omics Approaches., PMID:40207397
Proximity interactome of alphavirus replicase component nsP3 includes proviral host factors eIF4G and AHNAK., PMID:40193402
Sex and Depot Specific Adipocyte Proteome Profiling In Vivo via Intracellular Proximity Labeling., PMID:40181252
Circ_0090100 induces AHNAK expression to inhibit trophoblast cell proliferation and invasion and accelerate cell apoptosis by segregating miR-139-5p in preeclampsia., PMID:40063163
Identifying G-quadruplex-interacting proteins in cancer-related gene promoters., PMID:40025218
Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension., PMID:39965671
Loss of Glutathione-S-Transferase Theta 2 (GSTT2) Modulates the Tumor Microenvironment and Response to BCG Immunotherapy in a Murine Orthotopic Model of Bladder Cancer., PMID:39769061
Proteomic Profiling of Pre- and Post-Surgery Saliva of Glioblastoma Patients: A Pilot Investigation., PMID:39684695
Identification of key signaling pathways and novel computational drug target for oral cancer, metabolic disorders and periodontal disease., PMID:39674633
Harnessing Nanotechnology for Gout Therapy: Colchicine-Loaded Nanoparticles Regulate Macrophage Polarization and Reduce Inflammation., PMID:39665079
Impaired TGF-β signaling via AHNAK family mutations elicits an esophageal cancer subtype with sensitivities to genotoxic therapy and immunotherapy., PMID:39235488
Cancer-specific alterations in nuclear matrix proteins determined by multi-omics analyses of ductal carcinoma in situ., PMID:39165691
KLF7 promotes neuroblastoma differentiation through the GTPase signaling pathway by upregulating neuroblast differentiation-associated protein AHNAKs and glycerophosphodiesterase GDPD5., PMID:38924469
Circ6834 suppresses non-small cell lung cancer progression by destabilizing ANHAK and regulating miR-873-5p/TXNIP axis., PMID:38890620
PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells., PMID:38709899
Cancer-Specific Alterations in Nuclear Matrix Proteins Determined by Multi-omics Analyses of Ductal Carcinoma in Situ., PMID:38405693
Identification of AHNAK expression associated with the pathogenesis of chronic obstructive pulmonary disease by bioinformatic analysis., PMID:38051912
Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein., PMID:37962808
Expression of S100A16 Is Associated with Biological Aggressiveness and Poor Prognosis in Patients with Bladder Cancer Who Underwent Radical Cystectomy., PMID:37833982
Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets., PMID:37758692
Analysis of Zinc and Stromal Immunity in Disuse Osteoporosis: Mendelian Randomization and Transcriptomic Analysis., PMID:37752822
A human identification system for hair shaft using RNA polymorphism., PMID:37611365
Downregulation of AHNAK2 inhibits cell cycle of lung adenocarcinoma cells by interacting with RUVBL1., PMID:37349884
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms., PMID:37315111
Ahnak is required to balance calcium ion homeostasis and smooth muscle development in the urinary system., PMID:37308968
Neuropeptide Y regulates osteocyte phenotype and function through AHNAK-Smad signalling., PMID:37163251
AHNAK, regulated by the OSM/OSMR signaling, involved in the development of primary localized cutaneous amyloidosis., PMID:37100691
NAT10 Drives Cisplatin Chemoresistance by Enhancing ac4C-Associated DNA Repair in Bladder Cancer., PMID:36939377
Protein Expression Profiles in Exosomes of Bovine Mammary Epithelial Cell Line MAC-T Infected with Staphylococcus aureus., PMID:36939340
Transcriptomic analysis reveals the immune response of human microglia to a soy protein and collagen hybrid bioscaffold., PMID:36825181
New panel of biomarkers to discriminate between amelanotic and melanotic metastatic melanoma., PMID:36776379
Diagnostic and prognostic value of STAP1 and AHNAK methylation in peripheral blood immune cells for HBV-related hepatopathy., PMID:36713363
AHNAK Contributes to Hepatocellular Carcinoma Growth by Interacting with IGF-1R., PMID:36557813
Neuroblast Differentiation-Associated Protein Derived Polypeptides: AHNAK(5758-5775) Induces Inflammation by Activating Mast Cells via ST2., PMID:36511894
AHNAK-modified microbubbles for the intracranial delivery of triptolide: In-vitro and in-vivo investigations., PMID:36404486
Transcriptomic and proteomic characteristics of the di(2-ethylhexyl) phthalate-induced sperm dna damage mouse model., PMID:36356568
Downregulation of Circ_0088196 Contributes to the Development of Trophoblastic Cells through miR-133b Sponging Function to Affect the AHNAK Expression., PMID:36198257
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway., PMID:36089788
S100A10 and its binding partners in depression and antidepressant actions., PMID:36046712
Clinical Proteomics for Meningioma: An Integrated Workflow for Quantitative Proteomics and Biomarker Validation in Formalin-Fixed Paraffin-Embedded Tissue Samples., PMID:36036964
Integrated Analysis and Identification of Critical RNA-Binding Proteins in Bladder Cancer., PMID:35954405
Identification of COVID-19-Associated DNA Methylation Variations by Integrating Methylation Array and scRNA-Seq Data at Cell-Type Resolution., PMID:35885892
Inhibition of AHNAK nucleoprotein 2 alleviates pulmonary fibrosis by downregulating the TGF-β1/Smad3 signaling pathway., PMID:35882062
Ahnak depletion accelerates liver regeneration by modulating the TGF-β/Smad signaling pathway., PMID:35880432
Identification of proteome markers for drug-induced liver injury in zebrafish embryos., PMID:35868597
The AHNAK induces increased IL-6 production in CD4+ T cells and serves as a potential diagnostic biomarker for recurrent pregnancy loss., PMID:35766885
Synchronous polyostotic solid variant of aneurysmal bone cyst involving thoracic vertebrae and harboring a novel AHNAK::USP6 gene fusion. A case report and review., PMID:35717456