Catalog No.
YHG13801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro61-Ala170
Predicted molecular weight
14.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q07869
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Peroxisome proliferator-activated receptor alpha, PPAR, Nuclear receptor subfamily 1 group C member 1, PPAR-alpha, PPARA, NR1C1
Mitsugumin 53 drives stem cell differentiation easing intestinal injury and inflammation., PMID:40494851
Chlorogenic acid and ferulic acid in SMYAD alleviate diabetic cardiomyopathy by inhibiting cardiac lipotoxicity via GCGR/PPARα and GCGR/AMPK pathways., PMID:40466507
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways., PMID:40435181
ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A-activated PPARa signaling pathway., PMID:40419169
Mechanism Analysis of Zuogui and Yougui Pills on Diabetic Nephropathy Through Transcriptional Regulatory Networks of HIF1A and PPARA., PMID:40417738
Fetal macrosomia and placental expression of fibroblast growth factor 21 and peroxisome proliferator-activated receptor alpha., PMID:40411500
PPARα Genetic Deletion Reveals Global Transcriptional Changes in the Brain and Exacerbates Cerebral Infarction in a Mouse Model of Stroke., PMID:40362325
Oleoylethanolamide exerts neuroprotection following ischemic stroke through microglial PPARα signal., PMID:40359891
Study on the mechanism of Xanthoceras sorbifolia Bunge oil in the treatment of Alzheimer's disease by an integrated "network pharmacology-metabolomics" strategy., PMID:40340504
Effects of Pemafibrate on Cardio-Ankle Vascular Index (CAVI) in Patients with Type 2 Diabetes or Ischemic Heart Disease: A 24-Week Observational Study., PMID:40297799
Effects of lactoferrin on high-fat and high-cholesterol diet-induced non-alcoholic fatty liver disease in mice., PMID:40294723
PPAR-mediated reduction of lipid accumulation in hepatocytes involves the autophagy-lysosome-mitochondrion axis., PMID:40289698
Formononetin ameliorates depression-like behaviors through rebalancing microglia M1/M2 polarization and inhibiting NLRP3 inflammasome: involvement of activating PPARα-mediated autophagy., PMID:40275171
A signpost to guide the key therapeutic components of Aralia continentalis Kitag roots in treating T2DM-derived heart attack, and diabetic nephropathy via systems biology concept., PMID:40274257
A host enzyme reduces metabolic dysfunction-associated steatotic liver disease (MASLD) by inactivating intestinal lipopolysaccharide., PMID:40271687
PPARα regulates ER-lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes., PMID:40258152
Comparison of the impact of chlordecone and its metabolite chlordecol on genes involved in pesticide metabolism in HepG2 cell line., PMID:40252817
PPARɑ variant V227A reduces plasma triglycerides through enhanced lipoprotein lipolysis., PMID:40245984
Ablation of Mouse Selenium-Binding Protein 1 and 2 Elevates LDL by Disruption of Cholesterol Efflux and Lipid Metabolism., PMID:40244197
Integrating network pharmacology and experimental validation via PPAR signaling to ameliorate rheumatoid arthritis: Insights from Corydalis Decumbentis Rhizoma (Xiatianwu)., PMID:40239773
Transcriptional Response to Fasting Studied in the Liver of Mice That Express Phosphorylation Resistant Perilipin 5., PMID:40238664
ADH1C maintains the homeostasis of metabolic microenvironment to inhibit steatotic hepatocellular carcinoma., PMID:40233847
Unveiling the mechanism of amelioration of adjuvant-induced rheumatoid arthritis by Drynaria quercifolia rhizome extract using network pharmacology and gene expression-based studies., PMID:40199969
Identification of key immune genes of drug-induced liver injury induced by tolvaptan based on bioinformatics., PMID:40178603
Effects of microencapsulated essential oils and seaweed meal on growth performance, digestive enzymes, intestinal morphology, liver functions, and plasma biomarkers in broiler chickens., PMID:40151066
Changes in Vertical Jump Parameters After Training Unit in Relation to ACE, ACTN3, PPARA, HIF1A, and AMPD1 Gene Polymorphisms in Volleyball and Basketball Players., PMID:40149402
A Combined GLP-1/PPARa/CB1-Based Therapy to Restore the Central and Peripheral Metabolic Dysregulation Induced by a High-Fructose High-Fat Diet., PMID:40141063
Effects of candidate genes on milk fat synthesis in ruminants: A meta-analysis., PMID:40139354
Single-nucleus multiomic analysis of Beckwith-Wiedemann syndrome liver reveals PPARA signaling enrichment and metabolic dysfunction., PMID:40133415
Moringa oleifera Leaves Powder Mitigates Imidacloprid-Induced Neurobehavioral Disorders and Neurotoxic Reactions in Broiler Chickens by Regulating the Caspase-3/Hsp70/PGC-1α Pathway., PMID:40110847
[Mechanisms of 6-Hydroxygen Genistein in the Treatment of Pulmonary Injury in High-Altitude Hypoxic Mice]., PMID:40109471
CRSP8-driven fatty acid metabolism reprogramming enhances hepatocellular carcinoma progression by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling., PMID:40069732
Huangqi and Danshen improve the chronic nephrotoxicity of cyclosporin A by regulating lipid metabolism., PMID:40056636
Poncirin ameliorates alcoholic liver injury by regulating lipid metabolism and inflammatory response in a PPARα dependent manner., PMID:40056635
Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate., PMID:40036302
Perfluorooctanoic acid increases serum cholesterol in a PPARα-dependent manner in female mice., PMID:40021516
PCSK9 with a gain of function D374Y mutation aggravates atherosclerosis by inhibiting PPARα expression., PMID:40011664
Live yeast (Saccharomyces cerevisiae) improves growth performance and liver metabolic status of lactating Hu sheep., PMID:39986452
JTCD attenuates HF by inhibiting activation of HSCs through PPARα-TFEB axis-mediated lipophagy., PMID:39978277
Aurantio-Obtusin Regulates Gut Microbiota and Serum Metabolism to Alleviate High-Fat Diet-Induced Obesity-Associated Non-Alcoholic Fatty Liver Disease in Mice., PMID:39953693
A group of novel polyfluoroether substances affects lipid metabolism in human hepatocyte HepaRG cells less than classic perfluoroalkyl compounds., PMID:39952334
Overexpression of Apolipoprotein A-I Alleviates Insulin Resistance in MASLD Mice Through the PPARα Pathway., PMID:39940822
Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer's disease., PMID:39910202
A high-resolution bovine mitochondrial co-expression network., PMID:39898529
PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma., PMID:39890801
Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent manner., PMID:39888917
D-allulose enhances lipid oxidation in HepG2 cells via peroxisome proliferator-activated receptor α (PPARα)., PMID:39884381
The PPAR-α agonist oleoyethanolamide (OEA) ameliorates valproic acid-induced steatohepatitis in rats via suppressing Wnt3a/β-catenin and activating PGC-1α: Involvement of network pharmacology and molecular docking., PMID:39880183
Boeravinone C ameliorates lipid accumulation and inflammation in diabetic kidney disease by activating PPARα signaling., PMID:39880066
Metabolic effects of heterocyclic amines on insulin‑induced AKT phosphorylation and gluconeogenic gene expression are modified by N -acetyltransferase 2 genetic polymorphism., PMID:39878101
For research use only. Not for human or drug use.
