Catalog No.
YHG11301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His128-Val602
Predicted molecular weight
55.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q07065
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
p63, Climp-63, CKAP4, 63-kDa cytoskeleton-linking membrane protein, Cytoskeleton-associated protein 4
Cytoskeleton-associated protein 4 (CKAP4) affects podocyte cytoskeleton dynamics in diabetic kidney disease., PMID:40493405
Association Between CKAP4 Expression and Poor Prognosis in Patients with Bladder Cancer Treated with Radical Cystectomy., PMID:40282454
[Inhibition of osteogenic differentiation of mouse bone marrow mesenchymal stem cells and maxillary expansion osteogenesis by cytoskeleton-associated protein 4 knockout]., PMID:40268538
A Study of Immunohistochemical Expression of p63 in Colorectal Carcinoma., PMID:40091472
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis., PMID:40055343
Inhibition of IP3 (Inositol 1,4,5-Trisphosphate) Receptors Retards SARS-CoV-2-Induced Endothelial von Willebrand Factor Secretion and Thrombosis., PMID:40049586
Exosomal Biomarkers for Prognosis in Oral Squamous Cell Carcinoma-A Systematic Review of Emerging Technologies., PMID:40009435
The glycoprotein GPNMB protects against oxidative stress through enhanced PI3K/AKT signaling in epidermal keratinocytes., PMID:39947468
Chemoproteomics reveals proteome-wide covalent and non-covalent targets of withaferin A., PMID:39900821
DKK1 and Its Receptors in Esophageal Adenocarcinoma: A Promising Molecular Target., PMID:39795613
CKAP4 is a potential therapeutic target to overcome resistance to EGFR-TKIs in lung adenocarcinoma., PMID:39704929
CKAP4 in hepatocellular carcinoma: competitive RETREG1/FAM134B binding, reticulophagy regulation, and cancer progression., PMID:39689859
Royal Jelly Maintains Epidermal Stem Cell Properties by Repressing Senescence., PMID:39675970
ER quality control through reticulophagy and protein secretion., PMID:39603274
DKK3 as a diagnostic marker and potential therapeutic target for sarcopenia in chronic obstructive pulmonary disease., PMID:39571512
Retraction: A network map of cytoskeleton-associated protein 4 (CKAP4) mediated signaling pathway in cancer., PMID:39524144
Cancer cells sense solid stress to enhance metastasis by CKAP4 phase separation-mediated microtubule branching., PMID:39528501
Senescence Biomarkers CKAP4 and PTX3 Stratify Severe Kidney Disease Patients., PMID:39404377
Immunohistochemical evaluation of cyclin D1 and p63 in odontogenic keratocyst and unicystic ameloblastoma., PMID:39393896
DKK1 as a chemoresistant protein modulates oxaliplatin responses in colorectal cancer., PMID:39333078
Identification of immune-related biomarkers for intracerebral hemorrhage diagnosis based on RNA sequencing and machine learning., PMID:39281688
Identification of novel mitophagy-related biomarkers for Kawasaki disease by integrated bioinformatics and machine-learning algorithms., PMID:39263286
Cytosolic FKBPL and ER-resident CKAP4 co-regulates ER-phagy and protein secretion., PMID:39251576
Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma., PMID:39230995
Disposable Zirconium trisulfide-Reduced graphene oxide modified conducting thread based electrochemical biosensor for lung cancer diagnosis., PMID:39226732
Targeted DNA Sequencing in Diagnosis of Malignant Phyllodes Tumors With Emphasis on Tumors With Keratin and p63 Expression., PMID:39154782
Newly developed humanized anti-CKAP4 antibody suppresses pancreatic cancer growth by inhibiting DKK1-CKAP4 signaling., PMID:39118263
[Isolated intraductal carcinoma of the prostate: a clinicopathological and molecular analysis]., PMID:39103261
The Role of Serum Dickkopf1 and CKAP4 Levels in Diagnosing Colorectal Cancer and Measuring the Disease Severity: A Prospective Study., PMID:38929550
Promoter hypermethylation-induced downregulation of ITGA7 promotes colorectal cancer proliferation and migration by activating the PI3K/AKT/NF-κB pathway., PMID:38885843
Endoplasmic reticulum-plasma membrane contact gradients direct cell migration., PMID:38867038
Transcriptional profiles associated with coronary artery disease in type 2 diabetes mellitus., PMID:38706700
LRRC59 promotes the progression of oral squamous cell carcinoma by interacting with SRP pathway components and enhancing the secretion of CKAP4-containing exosomes., PMID:38533057
Invigorating human MSCs for transplantation therapy via Nrf2/DKK1 co-stimulation in an acute-on-chronic liver failure mouse model., PMID:38529014
DKK1 Activates the PI3K/AKT Pathway via CKAP4 to Balance the Inhibitory Effect on Wnt/β-Catenin Signaling and Regulates Wnt3a-Induced MSC Migration., PMID:38469899
Regulation of Cellular Signaling with an Aptamer Inhibitor to Impede Cancer Metastasis., PMID:38129955
CKAP4 and mutant p53 cooperatively abrogate cell cycle checkpoint to induce genotoxic resistance in ovarian cancer., PMID:37983936
The clinical significance and diagnostic value of serum Dickkopf1 and CKAP4 levels in patients with gastric cancer: a prospective study., PMID:37916373
Genomic Insights Into Statin Therapy: Differential Expression Analysis of Key Genes., PMID:37741602
Novel inflammatory biomarkers associated with stroke severity: results from a cross-sectional stroke cohort study., PMID:37468969
Disrupted epithelial permeability as a predictor of severe COVID-19 development., PMID:37422701
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma., PMID:37208923
The High Presence of HCMV pp71 Proteins, Correlate with P63 Expression in Pancreatic Cancer Tumor Tissue., PMID:37116169
CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer., PMID:37057110
Identification of diagnostic biomarks and immune cell infiltration in ulcerative colitis., PMID:37055577
Molecular basis of Climp63-mediated ER lumen spacing., PMID:37039099
A network map of cytoskeleton-associated protein 4 (CKAP4) mediated signaling pathway in cancer., PMID:36944905
Circular RNA suppression of vascular smooth muscle apoptosis through the miR-545-3p/CKAP4 axis during abdominal aortic aneurysm formation., PMID:36847199
DKK1-CKAP4 signal axis promotes hepatocellular carcinoma aggressiveness., PMID:36718957
Formin-like 2 promotes angiogenesis and metastasis of colorectal cancer by regulating the EGFL6/CKAP4/ERK axis., PMID:36715549
For research use only. Not for human or drug use.
