Catalog No.
YHG11201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr76-Gln282
Predicted molecular weight
25.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q07021
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hyaluronan-binding protein 1, SF2AP32, C1QBP, gC1q-R protein, SF2P32, Glycoprotein gC1qBP, Complement component 1 Q subcomponent-binding protein, mitochondrial, ASF/SF2-associated protein p32, GC1QBP, HABP1, p33, C1qBP, Mitochondrial matrix protein p32
Interactome of FMRP-N-tat therapeutic unveils key interactions for cellular function in Fragile X neurons., PMID:40480633
C1QBP promotes apoptosis of goat fetal turbinate cells via inhibiting the expression of TRIM5 or TNFSF10., PMID:40454173
C1QBP Modulates DNA Damage Response and Radiosensitivity in Hepatocellular Carcinoma by Regulating NF-κB Activity., PMID:40429658
Specificity protein 1 (SP1) plays an essential role in early bovine embryo development., PMID:40286422
Investigating the causal relationships between mitochondrial proteins and dementia with Lewy bodies., PMID:40111912
C1QBP Promotes Prostate Cancer Progression and Lipid Accumulation by Negatively Regulating ALDH9A1., PMID:40099576
CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis., PMID:39905216
Integrative pan-cancer genomic analysis highlights mitochondrial protein p32 as a potential therapeutic target in Myc-driven tumorigenesis., PMID:39891862
Exploring genetic associations and drug targets for mitochondrial proteins and schizophrenia risk., PMID:39863625
Omega-3 fatty acid supplementation from late pregnancy to early lactation attenuates the endocannabinoid system and immune proteome in preovulatory follicles and endometrium of Holstein dairy cows., PMID:39824496
A new peptide inhibitor of C1QBP exhibits potent anti-tumour activity against triple negative breast cancer by impairing mitochondrial function and suppressing homologous recombination repair., PMID:39748215
Identification of the whole genome of alternative splicing and RNA-binding proteins involved in nintedanib-induced apoptosis in gastric cancer cells., PMID:39726754
Exploring the causal effect of complement and IgA nephropathy-a Mendelian randomization study., PMID:39627156
Macrophages Promote Atherosclerosis Development by Inhibiting CD8T Cell Apoptosis., PMID:39345351
Identification of ribosome biogenesis genes and subgroups in ischaemic stroke., PMID:39290696
Molecular biomarkers involved in the progression of gallbladder inflammatory lesions to invasive cancer: A proteomic approach., PMID:39284282
Endogenous complement 1q binding protein (C1qbp) regulates mitochondrial permeability transition and post-myocardial infarction remodeling and dysfunction., PMID:39209214
RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release., PMID:39019044
Extracellular C1qbp inhibits myogenesis by suppressing NFATc1., PMID:38977785
Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interaction inhibits tumor progression via enhancing macrophage phagocytosis., PMID:38773982
The C1q and gC1qR axis as a novel checkpoint inhibitor in cancer., PMID:38711524
Inhibition of Multifunctional Protein p32/C1QBP Promotes Cytostatic Effects in Colon Cancer Cells by Altering Mitogenic Signaling Pathways and Promoting Mitochondrial Damage., PMID:38473963
Loss of CHCHD2 Stability Coordinates with C1QBP/CHCHD2/CHCHD10 Complex Impairment to Mediate PD-Linked Mitochondrial Dysfunction., PMID:38453793
Genetic and pharmacologic p32-inhibition rescue CHCHD2-linked Parkinson's disease phenotypes in vivo and in cell models., PMID:38395904
Novel oncogenic transcriptional targets of mutant p53 in esophageal squamous cell carcinoma., PMID:38358025
Isolation and target identification of anti-renal fibrosis compounds from Cordyceps militaris., PMID:38330722
C1QBP is a critical component in the immune response of large yellow croaker (Larimichthys crocea) against visceral white spot disease caused by Pseudomonas plecoglossicida., PMID:38218420
Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia., PMID:37798266
Genome-wide association study of abnormal elevation of ALT in patients exposed to atabecestat., PMID:37658353
Complement protein C1q stimulates hyaluronic acid degradation via gC1qR/HABP1/p32 in malignant pleural mesothelioma., PMID:37334363
The orf virus 129 protein can inhibit immune responses by interacting with host complement C1q binding protein in goat turbinate bone cells., PMID:37270925
A potential histone-chaperone activity for the MIER1 histone deacetylase complex., PMID:37099381
A novel protein encoded by circRsrc1 regulates mitochondrial ribosome assembly and translation during spermatogenesis., PMID:37095490
The double homeodomain protein DUX4c is associated with regenerating muscle fibers and RNA-binding proteins., PMID:36882853
Mitochondrial C1QBP is essential for T cell antitumor function by maintaining mitochondrial plasticity and metabolic fitness., PMID:36828964
A nucleolar long "non-coding" RNA encodes a novel protein that functions in response to stress., PMID:36812203
gC1qR: A New Target for Cancer Immunotherapy., PMID:36776869
C1QBP Mediates Breast Cancer Cell Proliferation and Growth via Multiple Potential Signalling Pathways., PMID:36674861
Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction., PMID:36476844
C1QBP regulates mitochondrial plasticity to impact tumor progression and antitumor immune response., PMID:36467687
C9-ALS-Associated Proline-Arginine Dipeptide Repeat Protein Induces Activation of NLRP3 Inflammasome of HMC3 Microglia Cells by Binding of Complement Component 1 Q Subcomponent-Binding Protein (C1QBP), and Syringin Prevents This Effect., PMID:36231090
Analysis of Ser/Thr Kinase HASPIN-Interacting Proteins in the Spermatids., PMID:36012324
gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII., PMID:35865516
The Mitochondrial Protein C1QBP Promotes Hepatocellular Carcinoma Progression by Enhancing Cell Survival, Migration and Invasion., PMID:35711850
C1QBP regulates apoptosis of renal cell carcinoma via modulating xanthine dehydrogenase (XDH) mediated ROS generation., PMID:35693733
Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0., PMID:35516420
An approach to p32/gC1qR/HABP1: a multifunctional protein with an essential role in cancer., PMID:35441886
Quantitative proteomic profiling of hepatocellular carcinoma at different serum alpha-fetoprotein level., PMID:35430532
Circular RNA MTCL1 promotes advanced laryngeal squamous cell carcinoma progression by inhibiting C1QBP ubiquitin degradation and mediating beta-catenin activation., PMID:35366893
Complement C1q Binding Protein (C1QBP): Physiological Functions, Mutation-Associated Mitochondrial Cardiomyopathy and Current Disease Models., PMID:35310974