Catalog No.
YHG10401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln19-Ile376
Predicted molecular weight
43.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06828
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen-binding 59 kDa protein, KSPG fibromodulin, FMOD, FM, Fibromodulin, Keratan sulfate proteoglycan fibromodulin, SLRR2E
Recombinant Small Leucine-Rich Proteoglycans Modulate Fiber Structure and Mechanical Properties of Collagen Gels., PMID:40509883
Premature cell senescence promotes vascular smooth muscle cell phenotypic modulation and resistance to re-differentiation., PMID:40493738
Construction of fibromodulin and borneol-clacked phosphorus dendrimer nanoparticles to reduce inflammation and oxidative stress in BBB to nursing care and ischemic stroke therapy., PMID:40411619
Fibromodulin-overexpressing fibroblast cells increase wound contraction, improve scar quality and enhance angiogenesis: an in-vivo study., PMID:40389960
Proteomic signatures of retinal pigment epithelium-derived exosomes in myopic and non-myopic tree shrew eyes., PMID:40330779
The profiling and analysis of gene expression in rat temporomandibular joint disc tissue and its derived cells., PMID:40329955
Overexpression of FMOD in Thyroid Carcinoma Triggers M1-Like Tumor-Associated Macrophage Polarization by Targeting Rap1B., PMID:40297936
Investigation on the role of Icariin in tendon injury repair: focusing on tendon stem cell differentiation., PMID:40234966
Fibromodulin selectively accelerates myofibroblast apoptosis in cutaneous wounds by enhancing interleukin 1β signaling., PMID:40221432
Spatial transcriptomic differences in the breast muscle of grower broilers at 21 and 28 days of age., PMID:40158281
Cardiac implications of chicken wooden breast myopathy., PMID:40110183
Comprehensive bioinformatics analysis of hub genes in ischemic heart failure and atrial fibrillation., PMID:40066352
Impact of therapeutic X-ray exposure on collagen I and associated proteins., PMID:40058620
Effects of GDF6 on active protein synthesis by cells of degenerated intervertebral disc., PMID:39920317
Changes in Gene Expression of the Extracellular Matrix in Patients with Full-Thickness Rotator Cuff Tears of Varying Sizes., PMID:39912080
Biomarkers of RV Dysfunction in HFrEF Identified by Direct Tissue Proteomics: Extracellular Proteins Fibromodulin and Fibulin-5., PMID:39823288
A Risk Model Based on Ferroptosis-Related Genes OSMR, G0S2, IGFBP6, IGHG2, and FMOD Predicts Prognosis in Glioblastoma Multiforme., PMID:39815665
Age-related remodeling of the vocal fold extracellular matrix composition, structure, and biomechanics during tissue maturation., PMID:39665313
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model., PMID:39592912
Identification of fibrosis-associated biomarkers in heart failure and human cancers., PMID:39563337
Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart., PMID:39492659
Carbon Fiber-Mediated Electrospinning Scaffolds Can Conduct Electricity for Repairing Defective Tendon., PMID:39288100
Integrative analysis regarding the correlation between collagen-related genes and prostate cancer., PMID:39174928
MiR-494-3p regulates skin fibroblast activities by mediating fibromodulin production., PMID:39129212
Key extracellular proteins and TF-miRNA co-regulatory network in diabetic foot ulcer: Bioinformatics and experimental insights., PMID:39037979
Integrative metabolomics and transcriptomics analysis revealed specific genes and metabolites affecting meat quality of chickens under different rearing systems., PMID:38991385
Identification of differentially expressed genes to predict the risk of heart failure in older patients with hypertrophic cardiomyopathy., PMID:38972072
FMOD Alleviates Depression-Like Behaviors by Targeting the PI3K/AKT/mTOR Signaling After Traumatic Brain Injury., PMID:38864941
Influence of feeding a soft diet on proteoglycan expression in rat temporomandibular joint discs., PMID:38830403
Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309
Exploration of the molecular linkage between endometriosis and Crohn disease by bioinformatics methods., PMID:38758892
Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging., PMID:38706856
Predictive Model to Identify the Long Time Survivor in Patients with Glioblastoma: A Cohort Study Integrating Machine Learning Algorithms., PMID:38662286
Transcriptomic and western blot characterisation of the human CLEFF4 clone, a new rapid cell line replacement for the Caco2 model., PMID:38641230
HAPLN1 knockdown inhibits heart failure development via activating the PKA signaling pathway., PMID:38580957
[Analysis of the types and functions of CD34+ cells in full-thickness skin defect wounds of normal mice and diabetic mice by single-cell RNA sequencing]., PMID:38548393
Fibromodulin facilitates the osteogenic effect of Masquelet's induced membrane by inhibiting the TGF-β/SMAD signaling pathway., PMID:38426394
The Essential Role of Proteoglycans and Glycosaminoglycans in Odontogenesis., PMID:38407002
Hub genes, a diagnostic model, and immune infiltration based on ferroptosis-linked genes in schizophrenia., PMID:38390236
Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis., PMID:38331776
Bioinformatic identification reveals a m6A-binding protein, IGF2BP2, as a novel tumor-promoting gene signature in thyroid carcinoma., PMID:38289368
Viable tendon neotissue from adult adipose-derived multipotent stromal cells., PMID:38260742
Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of fibromodulin., PMID:38172726
Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration., PMID:38092758
One Week of Single-Leg Immobilization Lowers Muscle Connective Protein Synthesis Rates in Healthy, Young Adults., PMID:37994085
Fibromodulin overexpression drives oral squamous cell carcinoma via activating downstream EGFR signaling., PMID:37965134
HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosis., PMID:37930124
Downregulation of fibromodulin attenuates inflammatory signaling and atrial fibrosis in spontaneously hypertensive rats with atrial fibrillation via inhibiting TLR4/NLRP3 signaling pathway., PMID:37904680
Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment., PMID:37884489
Methyl donor diet attenuates intimal hyperplasia after vascular injury in rats., PMID:37844765
For research use only. Not for human or drug use.
