Catalog No.
YHG10401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln19-Ile376
Predicted molecular weight
43.53 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06828
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Collagen-binding 59 kDa protein, KSPG fibromodulin, FMOD, FM, Fibromodulin, Keratan sulfate proteoglycan fibromodulin, SLRR2E
Note
For research use only.
Methyl donor diet attenuates intimal hyperplasia after vascular injury in rats., PMID:37844765
Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment., PMID:37884489
Downregulation of fibromodulin attenuates inflammatory signaling and atrial fibrosis in spontaneously hypertensive rats with atrial fibrillation via inhibiting TLR4/NLRP3 signaling pathway., PMID:37904680
HMGB2 is a potential diagnostic marker and therapeutic target for liver fibrosis and cirrhosis., PMID:37930124
Fibromodulin overexpression drives oral squamous cell carcinoma via activating downstream EGFR signaling., PMID:37965134
One Week of Single-Leg Immobilization Lowers Muscle Connective Protein Synthesis Rates in Healthy, Young Adults., PMID:37994085
Type I collagen and fibromodulin enhance the tenogenic phenotype of hASCs and their potential for tendon regeneration., PMID:38092758
Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of fibromodulin., PMID:38172726
Viable tendon neotissue from adult adipose-derived multipotent stromal cells., PMID:38260742
Bioinformatic identification reveals a m6A-binding protein, IGF2BP2, as a novel tumor-promoting gene signature in thyroid carcinoma., PMID:38289368
Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis., PMID:38331776
Hub genes, a diagnostic model, and immune infiltration based on ferroptosis-linked genes in schizophrenia., PMID:38390236
The Essential Role of Proteoglycans and Glycosaminoglycans in Odontogenesis., PMID:38407002
Fibromodulin facilitates the osteogenic effect of Masquelet's induced membrane by inhibiting the TGF-β/SMAD signaling pathway., PMID:38426394
[Analysis of the types and functions of CD34+ cells in full-thickness skin defect wounds of normal mice and diabetic mice by single-cell RNA sequencing]., PMID:38548393
HAPLN1 knockdown inhibits heart failure development via activating the PKA signaling pathway., PMID:38580957
Transcriptomic and western blot characterisation of the human CLEFF4 clone, a new rapid cell line replacement for the Caco2 model., PMID:38641230
Predictive Model to Identify the Long Time Survivor in Patients with Glioblastoma: A Cohort Study Integrating Machine Learning Algorithms., PMID:38662286
Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging., PMID:38706856
Exploration of the molecular linkage between endometriosis and Crohn disease by bioinformatics methods., PMID:38758892
Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309
Influence of feeding a soft diet on proteoglycan expression in rat temporomandibular joint discs., PMID:38830403
FMOD Alleviates Depression-Like Behaviors by Targeting the PI3K/AKT/mTOR Signaling After Traumatic Brain Injury., PMID:38864941
Identification of differentially expressed genes to predict the risk of heart failure in older patients with hypertrophic cardiomyopathy., PMID:38972072
Integrative metabolomics and transcriptomics analysis revealed specific genes and metabolites affecting meat quality of chickens under different rearing systems., PMID:38991385
Key extracellular proteins and TF-miRNA co-regulatory network in diabetic foot ulcer: Bioinformatics and experimental insights., PMID:39037979
MiR-494-3p regulates skin fibroblast activities by mediating fibromodulin production., PMID:39129212
Integrative analysis regarding the correlation between collagen-related genes and prostate cancer., PMID:39174928
Carbon Fiber-Mediated Electrospinning Scaffolds Can Conduct Electricity for Repairing Defective Tendon., PMID:39288100
Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart., PMID:39492659
Identification of fibrosis-associated biomarkers in heart failure and human cancers., PMID:39563337
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model., PMID:39592912
Age-related remodeling of the vocal fold extracellular matrix composition, structure, and biomechanics during tissue maturation., PMID:39665313
A Risk Model Based on Ferroptosis-Related Genes OSMR, G0S2, IGFBP6, IGHG2, and FMOD Predicts Prognosis in Glioblastoma Multiforme., PMID:39815665
Biomarkers of RV Dysfunction in HFrEF Identified by Direct Tissue Proteomics: Extracellular Proteins Fibromodulin and Fibulin-5., PMID:39823288
Changes in Gene Expression of the Extracellular Matrix in Patients with Full-Thickness Rotator Cuff Tears of Varying Sizes., PMID:39912080
Effects of GDF6 on active protein synthesis by cells of degenerated intervertebral disc., PMID:39920317
Impact of therapeutic X-ray exposure on collagen I and associated proteins., PMID:40058620
Comprehensive bioinformatics analysis of hub genes in ischemic heart failure and atrial fibrillation., PMID:40066352
Cardiac implications of chicken wooden breast myopathy., PMID:40110183
Spatial transcriptomic differences in the breast muscle of grower broilers at 21 and 28 days of age., PMID:40158281
Fibromodulin selectively accelerates myofibroblast apoptosis in cutaneous wounds by enhancing interleukin 1β signaling., PMID:40221432
Investigation on the role of Icariin in tendon injury repair: focusing on tendon stem cell differentiation., PMID:40234966
Overexpression of FMOD in Thyroid Carcinoma Triggers M1-Like Tumor-Associated Macrophage Polarization by Targeting Rap1B., PMID:40297936
The profiling and analysis of gene expression in rat temporomandibular joint disc tissue and its derived cells., PMID:40329955
Proteomic signatures of retinal pigment epithelium-derived exosomes in myopic and non-myopic tree shrew eyes., PMID:40330779
Fibromodulin-overexpressing fibroblast cells increase wound contraction, improve scar quality and enhance angiogenesis: an in-vivo study., PMID:40389960
Construction of fibromodulin and borneol-clacked phosphorus dendrimer nanoparticles to reduce inflammation and oxidative stress in BBB to nursing care and ischemic stroke therapy., PMID:40411619
Premature cell senescence promotes vascular smooth muscle cell phenotypic modulation and resistance to re-differentiation., PMID:40493738
Recombinant Small Leucine-Rich Proteoglycans Modulate Fiber Structure and Mechanical Properties of Collagen Gels., PMID:40509883
For research use only. Not for human or drug use.
