Catalog No.
YHG09501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala168-Thr314
Predicted molecular weight
19.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06546
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E4TF1A, Nuclear respiratory factor 2 subunit alpha, GABP subunit alpha, GABPA, GA-binding protein alpha chain, Transcription factor E4TF1-60
Transcriptional Regulators in the Cerebellum in Chronic Schizophrenia: Novel Possible Targets for Pharmacological Interventions., PMID:40332239
miR-450b-5p promotes development of endometriosis by inhibiting the GABPA/HOXD10 axis., PMID:39759007
The transcription factor GABPA is a master regulator of naive pluripotency., PMID:39747581
The transcription factor GABPA is a master regulator of naïve pluripotency., PMID:39605507
GABPA inhibits tumorigenesis in clear cell renal cell carcinoma by regulating ferroptosis through ACSL4., PMID:39489850
Inhibition of KDM4A restricts SQLE transcription and induces oxidative stress imbalance to suppress bladder cancer., PMID:39461328
BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer., PMID:39183149
A transcriptional regulatory mechanism of genes in the tricarboxylic acid cycle in the heart., PMID:39151728
Induction of Thymus Atrophy and Disruption of Thymocyte Development by Fipronil through Dysregulation of IL-7-Associated Genes., PMID:39141674
GABPA-Mediated Expression of HPN-AS1 Facilitates Cell Apoptosis and Inhibits Cell Proliferation in Hepatocellular Carcinoma by Promoting eIF4A3 Degradation., PMID:39114737
ESCCPred: a machine learning model for diagnostic prediction of early esophageal squamous cell carcinoma using autoantibody profiles., PMID:38956246
Unraveling the NRF2 confusion: Distinguishing nuclear respiratory factor 2 from nuclear erythroid factor 2., PMID:38815934
Epigenetically active chromatin in neonatal iWAT reveals GABPα as a potential regulator of beige adipogenesis., PMID:38765953
HiChIP-Based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 That Confers Genetic Susceptibility to Gastroesophageal Cancer., PMID:38748784
Crucial role of lncRNA NONHSAG037054.2 and GABPA, and their related functional networks, in ankylosing spondylitis., PMID:38628657
Multi-omics reveals changed energy metabolism of liver and muscle by caffeine after mice swimming., PMID:38188177
Using the Bayesian variational spike and slab model in a genome-wide association study for finding associated loci with bipolar disorder., PMID:38161273
Base editing of the mutated TERT promoter inhibits liver tumor growth., PMID:38016019
IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells., PMID:37798647
Expression of GABPA and HO-1 in classical Hodgkin's lymphoma and their clinical significance., PMID:37591756
Prohibitin2/PHB2, Transcriptionally Regulated by GABPA, Inhibits Cell Growth via PRKN/Parkin-dependent Mitophagy in Endometriosis., PMID:37587393
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas., PMID:36270249
Influence of Local Muscle Cooling on Mitochondrial-Related Gene Expression at Rest., PMID:36231330
Up-Regulation of RACGAP1 Promotes Progressions of Hepatocellular Carcinoma Regulated by GABPA via PI3K/AKT Pathway., PMID:35958019
Expression Profile and Molecular Basis of Cyclin-Dependent Kinases Regulatory Subunit 2 in Endometrial Carcinoma Detected by Diversified Methods., PMID:35693634
Compatibility rules of human enhancer and promoter sequences., PMID:35594906
Emerging mechanisms of telomerase reactivation in cancer., PMID:35568649
GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma., PMID:35549739
Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers., PMID:35440061
GABPA Expression in Endometrial Carcinoma: A Prognostic Marker., PMID:34306255
TERT and its binding protein: overexpression of GABPA/B in high grade gliomas., PMID:34194624
The piperine derivative HJ105 inhibits Aβ1-42-induced neuroinflammation and oxidative damage via the Keap1-Nrf2-TXNIP axis., PMID:33994056
Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning., PMID:33832990
TERT promoter alterations could provide a solution for Peto's paradox in rodents., PMID:33257697
Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types., PMID:33153500
Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors., PMID:32963030
TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends., PMID:32768523
Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation., PMID:32533922
Lysine-Specific Demethylase 1 Affects the Progression of Papillary Thyroid Carcinoma via HIF1α and microRNA-146a., PMID:32303750
Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines., PMID:32228178
HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2., PMID:32193099
GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours., PMID:32163919
Coenzyme Q10 Regulation of Apoptosis and Oxidative Stress in H2O2 Induced BMSC Death by Modulating the Nrf-2/NQO-1 Signaling Pathway and Its Application in a Model of Spinal Cord Injury., PMID:31915512
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer., PMID:31802036
Whey protein polymorphisms in Sudanese goat breeds., PMID:31782121
ω-3 fish oil fat emulsion preconditioning mitigates myocardial oxidative damage in rats through aldehydes stress., PMID:31336342
Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemia., PMID:31280495
Identification of GA-Binding Protein Transcription Factor Alpha Subunit (GABPA) as a Novel Bookmarking Factor., PMID:30836589
Characterization of human telomerase reverse transcriptase promoter methylation and transcription factor binding in differentiated thyroid cancer cell lines., PMID:30664813
How latent viruses cause breast cancer: An explanation based on the microcompetition model., PMID:30579323
For research use only. Not for human or drug use.
