Catalog No.
YHG07701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys40-Asn164
Predicted molecular weight
15.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06141
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Regenerating islet-derived protein 3-alpha, PAP1, Regenerating islet-derived protein III-alpha, Hepatointestinal pancreatic protein, REG-3-alpha, HIP, REG3A, Pancreatitis-associated protein 1, Human proislet peptide, PAP, HIP/PAP, Reg III-alpha
The Impact of Human Milk Oligosaccharides on Antibiotic-Induced Microbial Dysbiosis and Gut Inflammation in Mice., PMID:40426555
Effects of the regenerating gene family on DSS-induced ulcerative colitis in a mouse model., PMID:40300333
Ruxolitinib stopped before transplantation does not induce cytokine release in myelofibrosis., PMID:40274649
An Integrative Analysis of Transcriptome Combined with Machine Learning and Single-Cell RNA-Seq for the Common Biomarkers in Crohn's Disease and Kidney Stone Disease., PMID:40242727
Prediction and Prognostication of Acute Graft-Versus-Host Disease by MAGIC Biomarkers., PMID:40123552
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling., PMID:39966859
Lead time trajectory of blood-based protein biomarkers for detection of pancreatic cancer based on repeat testing., PMID:39793753
[Screening in Cystic Fibrosis in the Chilean population. Pilot project for screening in newborns]., PMID:39760624
Urinary proteomics identifies distinct immunological profiles of sepsis associated AKI sub-phenotypes., PMID:39695715
Transcriptome and WGCNA Analyses Reveal Key Genes Regulating Anthocyanin Biosynthesis in Purple Sprout of Pak Choi (Brassica rapa L. ssp. chinensis)., PMID:39519283
[The Value of REG3α, sST2, and TNFR1 in Risk Stratification and Prognostic Evaluation of Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation in Children]., PMID:39479849
Hemolymph protease-17b activates proHP6 to stimulate melanization and Toll signaling in Manduca sexta., PMID:39406299
Regenerating Family Member 3 Alpha Is Predictive of Mortality Following Emergent Large Vessel Occlusion., PMID:39337456
A negative feedback regulatory module comprising R3-MYB repressor MYBL2 and R2R3-MYB activator PAP1 fine-tunes high light-induced anthocyanin biosynthesis in Arabidopsis., PMID:39303008
Tumor suppressive role of the antimicrobial lectin REG3A targeting the O -GlcNAc glycosylation pathway., PMID:38975812
Serum biomarkers REG1A and REG3A combined with the traditional CEA represent a novel nomogram for the screening and risk stratification of colorectal cancer., PMID:38965192
Transcription factors BZR1 and PAP1 cooperate to promote anthocyanin biosynthesis in Arabidopsis shoots., PMID:38869214
Increased expression of REG3A promotes tumorigenic behavior in triple negative breast cancer cells., PMID:38840145
Reg3A Overexpression Facilitates Hepatic Metastasis by Altering Cell Adhesion in LoVo Colon Cancer Cells., PMID:38771249
Reduced expression of central innate defense molecules in pancreatic biopsies from subjects with Type 1 diabetes., PMID:38717484
Amphiregulin, ST2, and REG3α biomarker risk algorithms as predictors of nonrelapse mortality in patients with acute GVHD., PMID:38640195
Quantifying redox transcription factor dynamics as a tool to investigate redox signalling., PMID:38574974
A Validated Risk Stratification That Incorporates MAGIC Biomarkers Predicts Long-Term Outcomes in Pediatric Patients with Acute GVHD., PMID:38548227
The deletion of ppr2 interferes iron sensing and leads to oxidative stress response in Schizosaccharomyces pombe., PMID:38499131
Inflammation, the kynurenines, and mucosal injury during human experimental enterotoxigenic Escherichia coli infection., PMID:38430452
Differential gene expression (DGE) analysis in persons with a history of giardiasis., PMID:38170269
Galectin-3 predicts acute GvHD and overall mortality post reduced intensity allo-HCT: a BMT-CTN biorepository study., PMID:38110620
Tumor-suppressive effect of Reg3A in COAD is mediated by T cell activation in nude mice., PMID:38011786
A novel intergenic (between REG3A and CTNNA2-AS1)-ALK fusion responds to alectinib in lung adenocarcinoma., PMID:37922771
Association of inflammation-related markers and diabetic retinopathy severity in the aqueous humor, but not serum of type 2 diabetic patients., PMID:37883447
Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc)., PMID:37864000
Decoding the IBD paradox: A triadic interplay between REG3, enterococci, and NOD2., PMID:37708849
REG3A promotes proliferation and DDP resistance of ovarian cancer cells by activating the PI3K/Akt signaling pathway., PMID:37665173
[Effect of REG3A on proliferation and invasion of glioma cells by regulating PI3K/Akt signaling pathway]., PMID:37580268
Reg3γ: current understanding and future therapeutic opportunities in metabolic disease., PMID:37524871
Predicting diagnostic biomarkers associated with immune infiltration in Crohn's disease based on machine learning and bioinformatics., PMID:37496049
Daphnetin attenuates intestinal inflammation, oxidative stress, and apoptosis in ulcerative colitis via inhibiting REG3A-dependent JAK2/STAT3 signaling pathway., PMID:37209277
REG3A overexpression functions as a negative predictive and prognostic biomarker in rectal cancer patients receiving CCRT., PMID:37042618
Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice., PMID:36918710
A Pilot Study on Human Circulating System Indicated That Regenerating Islet-Derived Protein 3 Gamma (REG3A) is a Potential Prognostic Biomarker for Sepsis., PMID:36571936
Identification of regenerating island-derived protein 3E in dogs., PMID:36387376
Reg3α concentrations at day of allogeneic stem cell transplantation predict outcome and correlate with early antibiotic use., PMID:36350750
Protective effects of HTD4010, a Reg3a/PAP-derived peptide, in a mouse model of hypertriglyceridemic acute pancreatitis: Involvement of TLR4/NF-kappa B., PMID:36155057
A biomarker signature to predict complete response to itacitinib and corticosteroids in acute graft-versus-host disease., PMID:35689489
Decreased Plasma Level of Cytokeratin 20 (KRT20) Is Indicative of the Emergence and Severity of Acute GvHD Irrespective to the Type of Organ Involvement., PMID:35327321
Extracellular Vesicles as Biomarkers of Acute Graft-vs.-Host Disease After Haploidentical Stem Cell Transplantation and Post-Transplant Cyclophosphamide., PMID:35145514
Regenerating islet-derived protein 3 gamma (Reg3g) ameliorates tacrolimus-induced pancreatic β-cell dysfunction in mice by restoring mitochondrial function., PMID:35060126
Regenerating islet-derived protein 3-α is a prognostic biomarker for gastrointestinal chronic graft-versus-host disease., PMID:35030629
Elevated REG3α predicts refractory aGVHD in patients who received steroids-ruxolitinib as first-line therapy., PMID:34816294
The regenerating protein 3A: a crucial molecular with dual roles in cancer., PMID:34811636
For research use only. Not for human or drug use.
