Catalog No.
YHG01701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile252-Ala393
Predicted molecular weight
18.90 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q04695
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Keratin-17, CK-17, Cytokeratin-17, 39.1, Keratin, type I cytoskeletal 17, K17, KRT17
Transcriptomic Signature-Guided Depletion of Intermediate Alveolar Epithelial Cells Ameliorates Pulmonary Fibrosis in Mice., PMID:40470235
Hypoxia-induced RHCG as a key regulator in psoriasis and its modulation by secukinumab., PMID:40351602
Keratin-TMAO dressing accelerates full-thickness skin wound healing in diabetic rats via M2-macrophage polarization and the activation of PI3K/AKT/mTOR signaling pathway., PMID:40274140
Expression Distribution of Keratins in Normal and Pathological Corneas and the Regulatory Role of Krt17 on Limbal Stem Cells., PMID:40257786
Cytokeratin 17 activates AKT signaling to induce epithelial-mesenchymal transition and promote bladder cancer progression., PMID:40189507
Single-Cell Transcriptomic Analysis Reveals an Aggressive Basal-Like Tumor Cell Subpopulation Associated With Poor Prognosis in Intrahepatic Cholangiocarcinoma., PMID:39993788
Computational network analysis of two popular skin cancers provides insights into the molecular mechanisms and reveals common therapeutic targets., PMID:39866430
Novel Integration of Spatial and Single-Cell Omics Data Sets Enables Deeper Insights into IPF Pathogenesis., PMID:39846634
Mass spectrometric detection of keratins in tear fluid., PMID:39761842
Oral epithelial dysplasia with lichenoid features shares proteomic overlap with oral epithelial dysplasia without lymphocytic immune response., PMID:39706768
Regulation of keratinocyte barrier function and inflammatory response by the EGFR-STAT3 Pathway: Potential therapeutic implications of osimertinib and afatinib., PMID:39612655
The variant c.274A>G (p.Asn92Asp) in KRT17 in a patient with pachyonychia congenita and a novel clinical feature of acne inversa., PMID:39606016
Validation of Keratin 17 as a tissue biomarker in the diagnosis of upper tract urothelial carcinoma., PMID:39549749
The expression of keratin 17 and p27 predicts clinical outcomes in colorectal cancer., PMID:39529547
Epoxytiglianes induce keratinocyte wound healing responses via classical protein kinase C activation to promote skin re-epithelialization., PMID:39489221
Keratin 17 and A2ML1 are negative prognostic biomarkers in non-small cell lung cancer., PMID:39413460
Identification of Key Proteins Related to Cashmere Fiber Diameter by Integrated Proteomics and Bioinformatic Analyses in the Alpas and Alxa Goat Breeds., PMID:39336745
D2-40 and CK17 Immunohistochemistry as a Diagnostic Adjunct for HPV-Independent Squamous Lesions in the Vulva and Their Role in Defining Atypical Lichen Sclerosus., PMID:39285528
Oxidative Stress and Annexin A2 Differential Expression in Free Fatty Acids-Induced Non-Alcoholic Fatty Liver Disease in HepG2 Cells., PMID:39273539
Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner., PMID:39159283
Transcriptome-based classification to predict FOLFIRINOX response in a real-world metastatic pancreatic cancer cohort., PMID:39154856
Analysis of intracellular communication reveals consistent gene changes associated with early-stage acne skin., PMID:39143467
Dual and triple gene combinations of KRT5, KRT17, and S100A2 identify basal-like subtype of pancreatic ductal adenocarcinoma and correlate with survival outcome., PMID:39101950
Over-expression of KRT17 and MDK genes at mRNA levels in urine-exfoliated cells is associated with early non-invasive diagnosis of non-muscle-invasive bladder cancer., PMID:39069115
Mutational and transcriptional profile predicts the prognosis of stage IV gastric cancer - Prognostic factors for metastatic gastric cancer., PMID:39043541
Increased expression of keratin 17 in oral lichen planus and its correlation with disease severity., PMID:39035284
Expression patterns of keratin family members during tooth development and the role of keratin 17 in cytodifferentiation of stratum intermedium and stellate reticulum., PMID:39014890
A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870
Keratin 17 and Collagen type 1 genes: Esophageal cancer molecular marker discovery and evaluation., PMID:38979664
Transcriptome analysis of human dental pulp cells cultured on a novel cell-adhesive fragment by RNA sequencing., PMID:38901533
Cytokeratin 17 expression is commonly observed in keratinocytic skin tumours and controls tissue homeostasis impacting human papillomavirus protein expression., PMID:38878280
Lgr6-expressing functional nail stem-like cells differentiated from human-induced pluripotent stem cells., PMID:38743670
Keratin 17 is a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma., PMID:38642081
Enhancing upper tract urothelial carcinoma diagnosis: Utility of cytokeratin 17 and CK20/CD44/p53 immunohistochemical panel., PMID:38593961
Loss of mutant p53 in HaCaT keratinocytes promotes cadmium-induced keratin 17 expression and cell death., PMID:38547608
Exploring the Effect of Xiao-Chai-Hu Decoction on Treating Psoriasis Based on Network Pharmacology and Experiment Validation., PMID:38532341
Unlocking the Pancreatic Cancer Puzzle: Using Intermediate Cells to Target Treatment., PMID:38530840
Cross-sectional and longitudinal analyses of urinary extracellular vesicle mRNA markers in urothelial bladder cancer patients., PMID:38514751
MicroRNA-485-5p targets keratin17 to regulate pancreatic cancer cell proliferation and invasion via the FAK / SRC / ERK pathway., PMID:38434984
Diagnosis of verruciform acanthotic vulvar intra-epithelial neoplasia (vaVIN) using CK17, SOX2 and GATA3 immunohistochemistry., PMID:38356340
Evaluation of Cd-induced cytotoxicity in primary human keratinocytes., PMID:38174414
Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics., PMID:38163615
Pachyonychia Congenita Project: Advancing Research and Drug Development through Collaboration., PMID:38072449
In silico prediction and a systematic toxicology-based in vivo investigation uncovering the mechanism of aquatic toxicity caused by beta-lactam antibiotics., PMID:38065262
Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus., PMID:38033043
HIV gp120/Tat protein-induced epithelial-mesenchymal transition promotes the progression of cervical lesions., PMID:37981694
KRT17 from skin cells with high glucose stimulation promotes keratinocytes proliferation and migration., PMID:37929023
KRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment., PMID:37851080
Transcriptomic profiling of TLR-7-mediated immune-challenge in zebrafish embryos in the presence and absence of glucocorticoid-induced immunosuppression., PMID:37844410
Pachyonychia Congenita: Clinical Features and Future Treatments., PMID:37766547
For research use only. Not for human or drug use.
