Catalog No.
YHF99101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu23-Arg303
Predicted molecular weight
33.63 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q03405
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MO3, Urokinase plasminogen activator surface receptor, uPAR, UPAR, CD87, PLAUR, U-PAR, Monocyte activation antigen Mo3
Serum and urinary biomarkers in lupus nephritis: do suPAR and VEGF play a role?, PMID:40513062
Early neutrophil responses are potential biomarkers to predict severe COVID-19 in adults., PMID:40402813
The predictive value of suPAR for glomerular segmental sclerosis lesions in renal pathology., PMID:40364434
HIV-Tat upregulates the expression of senescence biomarkers in CD4+ T-cells., PMID:40342418
Soluble Urokinase Plasminogen Activator Receptor Predicts Survival and Hepatic Decompensation in Advanced Hepatocellular Carcinoma., PMID:40317602
Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels and Long-Term Cardiovascular Outcomes in Survivors of Breast Cancer: A UK Biobank Study., PMID:40314383
Plasma SuPAR and therapeutic response to erenumab in migraine: a REFORM study., PMID:40275185
Self-assembling sequentially administered tumor targeted Split IL-12p35 and p40 subunits to improve the therapeutic index of systemically delivered IL-12 therapy for cancer., PMID:40154091
The predictive value of postoperative soluble urokinase plasminogen activator receptor concentration for postoperative complications following valvular surgery., PMID:40088459
Soluble urokinase plasminogen activator receptor biomarker is not a predictor of mortality in high-risk hip fracture patients., PMID:40047907
Urokinase Plasminogen Activation System Modulation in Transformed Cell Lines., PMID:39859388
Inflammatory Markers and Measures of Cardiovascular Autonomic Neuropathy in Type 1 Diabetes., PMID:39727210
(Thio)chromenone derivatives exhibit anti-metastatic effects through selective inhibition of uPAR in cancer cell lines: discovery of an uPAR-targeting fluorescent probe., PMID:39668665
Role of plasma suPAR, sTNFR1, and sTNFR2 levels in risk stratification and outcome prediction of complicated acute kidney injury in elderly patients with coronavirus disease 2019., PMID:39561952
Significance of myeloperoxidase, pentraxin-3 and soluble urokinase plasminogen activator receptor determination in patients with moderate carotid artery stenosis., PMID:39508179
Transcriptomic analysis of profibrinolytic and fibrinolytic inhibitor genes in COVID-19 patients., PMID:39280271
Novel Biomarkers: Soluble Urokinase-Type Plasminogen Activator Receptor and Procalcitonin- and Histological Chorioamnionitis after Preterm Premature Rupture of Membranes., PMID:39227528
High-sensitive troponin T, suPAR and Beta-2-microglobulin changes in concentration during hemodialysis., PMID:39180468
A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge., PMID:38988231
CD87-targeted BiTE and CAR-T cells potently inhibit invasive nonfunctional pituitary adenomas., PMID:38987430
CHI3L1 on fibrinolytic system imbalance in chronic rhinosinusitis with nasal polyp., PMID:38975344
Prognostic Significance of Proteomics-Discovered Circulating Inflammatory Biomarkers in Patients With Pulmonary Arterial Hypertension., PMID:38874078
Associations between soluble urokinase plasminogen activator receptor (suPAR) concentration and psychiatric disorders - A systematic review and meta-analysis., PMID:38857636
Endothelial-specific Enhancer as a Cis Element of PLAUR Regulation by TNF-alpha, IL-1beta, and VEGF., PMID:38715331
Association of suPAR, ST2, and galectin-3 with eGFR decline and mortality in patients with advanced heart failure with reduced ejection fraction., PMID:38715217
The Role of Soluble Urokinase Plasminogen Activator Receptor (suPAR) as an Early Indicator of Mortality in Pediatric Septic Shock., PMID:38708489
Association between serum levels of GDF-15, suPAR, PIVKA-II, sdLDL and clinical outcomes in hospitalized COVID-19 patients., PMID:38700782
Gene Association Study of the Urokinase Plasminogen Activator and Its Receptor Gene in Alzheimer's Disease., PMID:38669542
PLAU promotes cell proliferation and migration of head and neck cancer via STAT3 signaling pathway., PMID:38663475
Analysis of the Predictive Efficacy of Serum suPAR Combined with APN and IgE Test and the Relationship of Patients with CHF and Cardiac Function., PMID:38581326
Circulating miR-10b, soluble urokinase-type plasminogen activator receptor, and plasminogen activator inhibitor-1 as predictors of non-small cell lung cancer progression and treatment response., PMID:38073374
Soluble urokinase plasminogen activator receptor, platelet aggregation, and carotid plaque thickness in diabetes: A cross-sectional analysis., PMID:38042098
Soluble Urokinase-Type Plasminogen Activator Receptor in Comatose Survivors After Out-of-Hospital Cardiac Arrest Treated with Targeted Temperature Management., PMID:37910781
Diagnostic value of soluble urokinase-type plasminogen activator receptor in patients with acute coronary syndrome: A systematic review and meta-analysis., PMID:37772350
Enhancing the invasive traits of breast cancers by CYP1B1 via regulation of p53 to promote uPAR expression., PMID:37661069
YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR., PMID:37552345
A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury-A Pilot Case Series., PMID:37511942
Circulating Soluble Urokinase Plasminogen Activator Receptor as a Predictive Indicator for COVID-19-Associated Acute Kidney Injury and Mortality: Clinical and Bioinformatics Analysis., PMID:37108340
PLAUR splicing pattern in hereditary angioedema patients' monocytes and macrophages., PMID:37086298
Plasma IL-6, TREM1, uPAR, and IL6/IL8 biomarkers increment further witnessing the chronic inflammation in type 2 diabetes., PMID:36848486
Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane., PMID:36638209
The Association of PLAUR Genotype and Soluble suPAR Serum Level with COVID-19-Related Lung Damage Severity., PMID:36555850
Analysis of Circulating Tumor and Cancer Stem Cells Provides New Opportunities in Diagnosis and Treatment of Small Cell Lung Cancer., PMID:36142766
TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR., PMID:35864968
Comprehensive analysis of the importance of PLAUR in the progression and immune microenvironment of renal clear cell carcinoma., PMID:35675366
Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View., PMID:35493073
Identification of a Novel Theranostic Signature of Metabolic and Immune-Inflammatory Dysregulation in Myocardial Infarction, and the Potential Therapeutic Properties of Ovatodiolide, a Diterpenoid Derivative., PMID:35163208
Chronic inflammation markers and cytokine-specific autoantibodies in Danish blood donors with restless legs syndrome., PMID:35102231
Soluble urokinase plasminogen activator receptor levels are predictive of COVID-19 severity in Afro-Caribbean patients., PMID:35081737
Plasma Gradient of Soluble Urokinase-Type Plasminogen Activator Receptor Is Linked to Pathogenic Plasma Proteome and Immune Transcriptome and Stratifies Outcomes in Severe COVID-19., PMID:34777349