Catalog No.
YHF98101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Ser408
Predicted molecular weight
48.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q03154
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aminoacylase-1, ACY1, ACY-1, N-acyl-L-amino-acid amidohydrolase
Comprehensive analysis of chronic hepatitis B concurrent with non-alcoholic fatty liver disease: a proteomics report based on clinical liver samples., PMID:40361009
Identification of Novel Mosaic Variants in Focal Epilepsy-Associated Patients' Brain Lesions., PMID:40282380
Integrated ubiquitomics characterization of hepatocellular carcinomas., PMID:39348425
FYN-mediated phosphorylation of BCKDK at Y151 promotes GBM proliferation by increasing the oncogenic metabolite N-acetyl-L-alanine., PMID:39170503
Proteomics profiling and association with cardiorenal complications in type 2 diabetes subtypes in Asian population., PMID:39059739
Knock-Out of ACY-1 Like Gene in Spodoptera litura Supports the Notion that FACs Improve Nitrogen Metabolism., PMID:38913104
Integrated analysis of muscle transcriptome, miRNA, and proteome of Chinese indigenous breed Ningxiang pig in three developmental stages., PMID:38808333
Cell non-autonomous signaling through the conserved C. elegans glycopeptide hormone receptor FSHR-1 regulates cholinergic neurotransmission., PMID:38405708
Proteomic and Metabolomic Signatures of Diet Quality in Young Adults., PMID:38337712
Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 deficiency., PMID:37852579
A novel co-target of ACY1 governing plasma membrane translocation of SphK1 contributes to inflammatory and neuropathic pain., PMID:37378314
The Ras small GTPase RSR1 regulates cellulase production in Trichoderma reesei., PMID:37218014
Sulfate-modified nanosized polystyrene impairs memory by inhibiting ionotropic glutamate receptors and the cAMP-response element binding protein (CREB) pathway in Caenorhabditis elegans., PMID:36868277
Chromatin Remodeling Factor SMARCA5 is Essential for Hippocampal Memory Maintenance via Metabolic Pathways in Mice., PMID:36807260
ACY1 Downregulation Enhances the Radiosensitivity of Cetuximab-Resistant Colorectal Cancer by Inactivating the Wnt/β-Catenin Signaling Pathway., PMID:36428796
Serum concentrations of aminoacylase 1 in schizophrenia as a potential biomarker: a case-sibling-control study., PMID:35791057
Transcriptome Analysis Reveals Crosstalk between the Abscisic Acid and Jasmonic Acid Signaling Pathways in Rice-Mediated Defense against Nilaparvata lugens., PMID:35682997
Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites., PMID:35568032
Identification and Validation of Novel Serum Autoantibodies Biomarkers for Staging Liver Fibrosis in Patients With Chronic Hepatitis B., PMID:35059422
Aminoacylase-1 plays a key role in myocardial fibrosis and the therapeutic effects of 20(S)-ginsenoside Rg3 in mouse heart failure., PMID:34916608
Obesogenic effect of erythromycin on Caenorhabditis elegans through over-eating and lipid metabolism disturbances., PMID:34863891
Proteomic analysis identifies deregulated metabolic and oxidative-associated proteins in Italian intrahepatic cholangiocarcinoma patients., PMID:34320944
Effect of the ACY-1 gene on HER2 and TRAIL expression in rectal carcinoma., PMID:34131440
LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma., PMID:34002044
Aminoacylase 1 (ACY-1) Mediates the Proliferation and Migration of Neuroblastoma Cells in Humans Through the ERK/Transforming Growth Factor β (TGF-β) Signaling Pathways., PMID:33619241
Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk., PMID:33591955
Absence of metabotropic glutamate receptor homolog(s) accelerates acetylcholine neurotransmission in Caenorhabditis elegans., PMID:33493646
A novel missense pathogenic variant in NEFH causing rare Charcot-Marie-Tooth neuropathy type 2CC., PMID:32780247
Characterization of Parkinson's disease using blood-based biomarkers: A multicohort proteomic analysis., PMID:31603904
Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics., PMID:31587987
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation., PMID:30297859
Liver transcriptome analysis reveals extensive transcriptional plasticity during acclimation to low salinity in Cynoglossus semilaevis., PMID:29914359
Study of the expression and function of ACY1 in patients with colorectal cancer., PMID:28454420
Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme., PMID:28160000
Identification and clinical significance of an elevated level of serum aminoacylase-1 autoantibody in patients with hepatitis B virus-related liver cirrhosis., PMID:27633755
De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome., PMID:27545680
MicroRNA-34a Promotes Hepatic Stellate Cell Activation via Targeting ACSL1., PMID:26437572
Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice., PMID:25645620
Isolated mild intellectual disability expands the aminoacylase 1 phenotype spectrum., PMID:24997716
Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease., PMID:24913063
Proteomics-based identification of the tumor suppressor role of aminoacylase 1 in hepatocellular carcinoma., PMID:24846301
Aminoacylase I deficiency due to ACY1 mRNA exon skipping., PMID:24117009
N-Acetylcysteine affects obesity-related protein expression in 3T3-L1 adipocytes., PMID:24112955
Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation., PMID:23739232
Caenorhabditis-in-drop array for monitoring C. elegans quiescent behavior., PMID:23633751
A novel panel of biomarkers in distinction of small well-differentiated HCC from dysplastic nodules and outcome values., PMID:23537217
Overexpression of aminoacylase 1 is associated with colorectal cancer progression., PMID:23317546
Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides., PMID:22349737
Roles of protein kinase A and adenylate cyclase in light-modulated cellulase regulation in Trichoderma reesei., PMID:22286997
Modulation of 11β-hydroxysteroid dehydrogenase 1 by β2-adrenoceptor in the ischaemia-reperfused rat kidney., PMID:22187316
For research use only. Not for human or drug use.
