Catalog No.
YHF97301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg18-Trp215
Predicted molecular weight
25.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q03013
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GSTM4-4, Glutathione S-transferase Mu 4, GSTM4, GST-Mu2, Leukotriene C4 synthase GSTM4, GST class-mu 4
A genome-wide base-editing screen uncovers a pivotal role of paxillin δ ubiquitination in influenza virus infection., PMID:40434888
Potential therapeutic targets for bladder cancer: a proteome-wide Mendelian randomization study., PMID:40226474
LIN28B enhances the chemosensitivity of colon cancer cells via inducing genomic instability by upsetting the balance between the production and removal of reactive oxygen species., PMID:39986369
Integrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading., PMID:39858409
Lung cancer, platinum analog-based frontline treatment and pharmacogenetic limitations., PMID:39560009
Evaluation of the role of hepatic Gstm4 in diet-induced obesity and dyslipidemia., PMID:39481188
Altered Levels of Gene Expression of Drug Metabolism Enzymes in Rat Brain Following Kainic Acid Treatment., PMID:39224027
Multi-omics Mendelian randomization integrating GWAS, eQTL and pQTL data revealed GSTM4 as a potential drug target for migraine., PMID:39039470
Comprehensive analysis of the prognostic value of glutathione S-transferases Mu family members in breast cancer., PMID:38922769
A quantitative proteomic study reveals oxidative stress and synapse-related proteins contributed to TDCIPP exposure induced neurotoxicity., PMID:38262093
Construction of novel 7 integrin-related gene signatures in thyroid cancer construction of model based on integrin genes., PMID:38115319
6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4., PMID:36928896
Reversal of High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Metformin Combined with PGG, an Inducer of Glycine N-Methyltransferase., PMID:36077467
Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance., PMID:35847493
Identification of significant prognostic risk markers for pancreatic ductal adenocarcinoma: a bioinformatic analysis., PMID:35675627
Sesame lignans upregulate glutathione S-transferase expression and downregulate microRNA-669c-3p., PMID:35433163
Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension., PMID:34803695
[Quantitative analysis of differential proteins in liver tissues of patients with non-alcoholic steatohepatitis using iTRAQ technology]., PMID:34658353
Proteomic Reveals Reasons for Acquired Drug Resistance in Lung Cancer Derived Brain Metastasis Based on a Newly Established Multi-Organ Microfluidic Chip Model., PMID:33415100
Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma., PMID:32855269
Quantitative analysis of differentially expressed proteins in psoriasis vulgaris using tandem mass tags and parallel reaction monitoring., PMID:32817748
Identification and validation of m6A RNA methylation regulators with clinical prognostic value in Papillary thyroid cancer., PMID:32514248
Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer., PMID:31602160
Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity., PMID:28478157
Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury., PMID:26169370
Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity., PMID:25467400
Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice., PMID:24285747
Effect of GSTM2-5 polymorphisms in relation to tobacco smoke exposures on lung function growth: a birth cohort study., PMID:24004509
Heterologous expression and functional characterization of avian mu-class glutathione S-transferases., PMID:23712008
The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells., PMID:23675469
Maternal and offspring xenobiotic metabolism haplotypes and the risk of childhood acute lymphoblastic leukemia., PMID:23433810
Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes., PMID:23111281
Elevated hepatic iron activates NF-E2-related factor 2-regulated pathway in a dietary iron overload mouse model., PMID:22649188
Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice., PMID:22496397
Effects of aging on mRNA profiles for drug-metabolizing enzymes and transporters in livers of male and female mice., PMID:22446518
Nuclear receptor HNF4α binding sequences are widespread in Alu repeats., PMID:22085832
Expression of GSTM4 and GSTT1 in patients with Tinea versicolor, Tinea inguinalis and Tinea pedis infections: a preliminary study., PMID:21771003
Immunohistochemical localization of glutathione s-transferase isoenzymes (gsta, Gstp, Gstm4, And Gstt1) and tumour marker p53 in matched tissue from normal larynx and laryngeal carcinoma: correlations with prognostic factors., PMID:20828517
The expression of GST isoenzymes and p53 in non-small cell lung cancer., PMID:20529827
Global gene expression profiles of ischemic preconditioning in deceased donor liver transplantation., PMID:20440768
Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy., PMID:20200426
Expression of glutathione-S-transferases isoenzymes and p53 in exfoliated human bladder cancer cells., PMID:19926314
Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1., PMID:19856098
Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor., PMID:19850644
Comparative gene expression of intestinal metabolizing enzymes., PMID:19746353
GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance., PMID:19718047
Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function., PMID:19151192
Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva., PMID:18270968
Microarray analysis of gene expression profile of multidrug resistance in pancreatic cancer., PMID:18028764
Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice., PMID:17890767
For research use only. Not for human or drug use.
