Catalog No.
YHF97101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu208-Glu330
Predicted molecular weight
16.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02985
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complement factor H-related protein 3, FHR-3, CFHR3, CFHL3, FHR3, DOWN16, H factor-like protein 3
Factor H-related 1 and heparan sulfate architecture contribute to complement dysregulation in C3 glomerulopathy., PMID:40453077
Pregnancy-related Thrombotic Microangiopathy has a spectrum of underlying causes., PMID:40306205
Pregnancy and delivery in the context of hemolytic uremic syndrome: A surrogacy case report., PMID:40183758
Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies., PMID:39753879
Shiga toxin-producing Escherichia coli infection as a precipitating factor for atypical hemolytic-uremic syndrome., PMID:39347991
Shared germline genomic variants in two patients with double primary gastrointestinal stromal tumours (GISTs)., PMID:39153853
[Clinical characteristics and genetic profile of complement system in renal thrombotic microangiopathy in patients with severe forms of arterial hypertension]., PMID:39106497
Case report: A family of atypical hemolytic uremic syndrome involving a CFH::CFHR1 fusion gene and CFHR3-1-4-2 gene duplication., PMID:38524137
A case of non-lupus full-house nephropathy diagnosed by kidney biopsy but observed IgA nephropathy on second biopsy., PMID:38421587
Complement dysregulation associated with a genetic variant in factor H-related protein 5 in atypical hemolytic uremic syndrome., PMID:37955705
Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy., PMID:37861398
Evaluation of the significance of complement-related genes mutations in atypical postinfectious glomerulonephritis: a pilot study., PMID:37845399
Several potential serum proteomic biomarkers for diagnosis of osteoarticular tuberculosis based on mass spectrometry., PMID:37353136
A single-center experience of post-transplant atypical hemolytic uremic syndrome., PMID:37288831
An inflammation-associated ferroptosis signature optimizes the diagnosis, prognosis evaluation and immunotherapy options in hepatocellular carcinoma., PMID:37248957
ACE2 negatively regulates the Warburg effect and suppresses hepatocellular carcinoma progression via reducing ROS-HIF1α activity., PMID:37215979
Atypical haemolytic uremic syndrome with refractory multiorgan involvement and heterozygous CFHR1/CFHR3 gene deletion., PMID:37147581
Proteomics reveals specific biological changes induced by the normothermic machine perfusion of donor kidneys with a significant up-regulation of Latexin., PMID:37041202
The absence of CFHR3 and CFHR1 genes from the T2T-CHM13 assembly can limit the molecular diagnosis of complement-related diseases., PMID:37032353
A Systematic Investigation of Complement and Coagulation-Related Protein in Autism Spectrum Disorder Using Multiple Reaction Monitoring Technology., PMID:37031449
Meningococcal factor H-binding protein: implications for disease susceptibility, virulence, and vaccines., PMID:36941192
Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new therapeutic agents for hepatocellular carcinoma., PMID:36860314
CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome., PMID:36793547
What lies in-between: C3 glomerulopathy with non-hemolytic renal microangiopathy and an ultra-rare C3 variant., PMID:36473547
Anti-factor H antibody and its role in atypical hemolytic uremic syndrome., PMID:36091034
Benefits of genetic and immunohistochemical markers in understanding abnormalities in aging retina., PMID:36074675
An Infant Case of Streptococcus Pneumoniae-Associated Thrombotic Microangiopathy with Heterozygous CFI Mutation and CFHR3-CFHR1 Deletion., PMID:36070894
Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations., PMID:36007525
The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma., PMID:35852862
Complement Factor H and Related Proteins as Markers of Cardiovascular Risk in Pediatric Chronic Kidney Disease., PMID:35740418
Copy number variation analysis using next-generation sequencing identifies the CFHR3/CFHR1 deletion in atypical hemolytic uremic syndrome: a case report., PMID:35617302
A novel hypoxia-driven gene signature that can predict the prognosis of hepatocellular carcinoma., PMID:35549979
Mycoplasma pneumoniae Infection Associated with Anti-Factor H Autoantibodies in Atypical Hemolytic Uremic Syndrome., PMID:35405682
Unraveling Structural Rearrangements of the CFH Gene Cluster in Atypical Hemolytic Uremic Syndrome Patients Using Molecular Combing and Long-Fragment Targeted Sequencing., PMID:35398599
Molecular Composition of Serum Exosomes Could Discriminate Rectal Cancer Patients with Different Responses to Neoadjuvant Radiotherapy., PMID:35205741
Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells., PMID:34819935
High prevalence of CFHR deletions in Indian women with pregnancy-associated hemolytic uremic syndrome., PMID:34796567
Atypical Hemolytic Uremic Syndrome after ChAdOx1 nCoV-19 Vaccination in a Patient with Homozygous CFHR3/CFHR1 Gene Deletion., PMID:34724668
Anti-Factor H Antibody-Associated Atypical Hemolytic Uremic Syndrome: A Case Report., PMID:34699711
Thrombotic microangiopathy associated with arboviral infection: Report of 3 cases., PMID:34648498
Protective chromosome 1q32 haplotypes mitigate risk for age-related macular degeneration associated with the CFH-CFHR5 and ARMS2/HTRA1 loci., PMID:34563268
Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome in a Patient With Heterozygous CFHR3/CFHR1 Deletion Treated With Eculizumab., PMID:34366267
Thrombotic microangiopathy in a patient with systemic lupus erythematosus and anti-factor H autoantibodies., PMID:34269998
Identification of significant potential signaling pathways and differentially expressed proteins in patients with wheat intolerance based on quantitative proteomics., PMID:34217887
CFH and CFHR Copy Number Variations in C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis., PMID:34211499
Clinical and Genetic Characteristics of Atypical Hemolytic Uremic Syndrome in Children: A Chinese Cohort Study., PMID:33873197
Complement Genetic Variants and FH Desialylation in S. pneumoniae-Haemolytic Uraemic Syndrome., PMID:33777036
Mining of RNA Methylation-Related Genes and Elucidation of Their Molecular Biology in Gallbladder Carcinoma., PMID:33718182
IgM Autoantibodies to Complement Factor H in Atypical Hemolytic Uremic Syndrome., PMID:33712527
For research use only. Not for human or drug use.
