Catalog No.
YHF95901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln636-Pro727
Predicted molecular weight
37.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02809
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5 % trehalose, 5 %mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1, Lysyl hydroxylase 1, LH1, PLOD, PLOD1, LLH
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy., PMID:40339550
Novel variations in the PLOD1, COL1A1, COL5A2 and COL4A1 genes related to keratoconus., PMID:40201566
Lysine hydroxylase 1 (PLOD1) regulates glucose metabolism and promotes Th17 cell differentiation in psoriasis., PMID:40088025
Increasing collagen synthesis in fibroblasts: The roles of PCL microspheres and the SAMD11-PLOD1 axis in skin rejuvenation., PMID:40074205
Synergistic Anti-Aging Effects of Adipose-Derived Stem Cell Extracellular Vesicles Loaded With Natural Compounds., PMID:39924347
PLOD1 promote proliferation and migration with glycolysis via the Wnt/β-catenin pathway in THCA., PMID:39424162
Hypoxia and Foxn1 alter the proteomic signature of dermal fibroblasts to redirect scarless wound healing to scar-forming skin wound healing in Foxn1-/- mice., PMID:39256768
Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction., PMID:39098433
Systematic characterization of the expression, prognosis and immune characteristics of PLOD family genes in breast cancer., PMID:39068670
Whole-exome sequencing screening for candidate genes and variants associated with primary sporadic keratoconus in Chinese patients., PMID:38908538
LncRNA FOXD2-AS1 promotes the growth, invasion and migration of OSCC cells by regulating the MiR-185-5p/PLOD1/Akt/mTOR pathway., PMID:38729078
SIRT6 deficiency causes ovarian hypoplasia by affecting Plod1-related collagen formation., PMID:37936548
Identification and characterization of putative biomarkers and therapeutic axis in Glioblastoma multiforme microenvironment., PMID:37538397
Identification of DDIT4 as a potential prognostic marker associated with chemotherapeutic and immunotherapeutic response in triple-negative breast cancer., PMID:37391802
Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase., PMID:37262099
Comprehensive Analysis of the Expression, Prognosis, and Biological Significance of PLOD Family in Bladder Cancer., PMID:36872941
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages., PMID:36695693
Transcriptome analysis of a dog model of congestive heart failure shows that collagen-related 2-oxoglutarate-dependent dioxygenases contribute to heart failure., PMID:36581661
Whole-genome sequencing unravels novel genetic determinants and regulatory pathways associated with triamcinolone acetonide-induced ocular hypertension., PMID:36222912
Kyphoscoliotic Ehlers-Danlos syndrome caused by pathogenic variants in FKBP14: Further insights into the phenotypic spectrum and pathogenic mechanisms., PMID:36054293
Methylglyoxal - an advanced glycation end products (AGEs) precursor - Inhibits differentiation of human MSC-derived osteoblasts in vitro independently of receptor for AGEs (RAGE)., PMID:35995334
Modulation of blood pressure regulatory genes in the Agtrap-Plod1 locus associated with a deletion in Clcn6., PMID:35927940
Identification and Validation of Aging-Related Genes in Alzheimer's Disease., PMID:35615282
TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer., PMID:35581606
Collagen type XIX regulates cardiac extracellular matrix structure and ventricular function., PMID:35346795
Overexpressing PLOD Family Genes Predict Poor Prognosis in Pancreatic Cancer., PMID:35330878
CD73+ adipose-derived stem cells reduce scar formation through PLOD1., PMID:35282129
Clinical Prognostic Value of the PLOD Gene Family in Lung Adenocarcinoma., PMID:35265665
P3H4 and PLOD1 expression associates with poor prognosis in bladder cancer., PMID:35149972
Bioinformatic analysis of PLOD family member expression and prognostic value in non-small cell lung cancer., PMID:35116582
First reported case of fragile foal syndrome type 1 in the Thoroughbred caused by PLOD1 c.2032G>A., PMID:34939209
Mating Stimulates the Immune Response and Sperm Storage-Related Genes Expression in Spermathecae of Bumblebee (Bombus terrestris) Queen., PMID:34899871
PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway., PMID:34845571
Connective Tissue Disorders in Domestic Animals., PMID:34807427
Posttranscriptional control of PLOD1 in adipose-derived stem cells regulates scar formation through altering macrophage polarization., PMID:34790779
PLOD1 promotes cell growth and aerobic glycolysis by regulating the SOX9/PI3K/Akt/mTOR signaling pathway in gastric cancer., PMID:34455762
New mechanistic insights to PLOD1-mediated human vascular disease., PMID:34400365
Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3., PMID:34304093
D-2-hydroxyglutarate dehydrogenase in breast carcinoma as a potent prognostic marker associated with proliferation., PMID:34296423
Clinical and molecular characteristics of 168 probands and 65 relatives with a clinical presentation of classical Ehlers-Danlos syndrome., PMID:34265140
Two novel variants in PLOD1 causing hydrocephalus in female newborn with kyphoscoliotic Ehlers-Danlos syndrome., PMID:34161861
Potential prognostic markers and significant lncRNA-mRNA co-expression pairs in laryngeal squamous cell carcinoma., PMID:34131588
Defining the Extracellular Matrix of Rhabdomyosarcoma., PMID:33708626
Circadian time series proteomics reveals daily dynamics in cartilage physiology., PMID:33610821
A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report., PMID:33579342
PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43., PMID:33483598
Quantitative STAU2 measurement in lymphocytes for breast cancer risk assessment., PMID:33441653
Hypoxia-induced PLOD1 overexpression contributes to the malignant phenotype of glioblastoma via NF-κB signaling., PMID:33420370
The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma., PMID:33287763
PLOD1 Is a Prognostic Biomarker and Mediator of Proliferation and Invasion in Osteosarcoma., PMID:33134376
For research use only. Not for human or drug use.
