Catalog No.
YHF94701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His391
Predicted molecular weight
44.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02548
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
B-cell-specific transcription factor, Paired box protein Pax-5, BSAP, PAX5
Primary Mediastinal Large B-cell Lymphoma: A Diagnostic Conundrum., PMID:40487560
Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses., PMID:40337516
scRNA-seq reveals that VEGF signaling mediates the response to neoadjuvant anlotinib combined with PD-1 blockade therapy in non-small cell lung cancer., PMID:40281576
Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation., PMID:40241172
RNA-sequencing: A reliable tool to unveil transcriptional landscape of paediatric B-other acute lymphoblastic leukaemia., PMID:40159352
[Composite diffuse large B-cell lymphoma and CD5-negative mantle cell lymphoma: report of a case]., PMID:40159032
Author Correction: Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:40119193
Immune training enhances anti-viral responses and improves outcomes in Pax5-/+ mice susceptible to chronic infection., PMID:40082582
Disruption of the sorcin‒PAX5 protein‒protein interaction induces ferroptosis by promoting the FBXL12-mediated ubiquitination of ALDH1A1 in pancreatic cancer., PMID:40055736
The significance of PAX5 in Merkel cell carcinoma., PMID:40034069
Genetic Diversity in KMT2A -r and KMT2A -Wt Groups: Assessing the Prognostic Value of Markers in BCP-ALL Among Infants., PMID:40000924
A novel stroma-dependent leukemia cell line from a patient with mixed-phenotype acute leukemia with Ph chromosome and PAX5 mutation., PMID:39979768
Immunohistochemical identification of immune cell subsets in formalin- and zinc-fixed, paraffin-embedded tissues from chicken and duck using commercial antibodies., PMID:39938274
Revisiting the Role of Long Non-coding RNA PSMA3-AS1 in Human Cancers: Current Evidence and Future Directions., PMID:39901687
CD3/CD20/CD45 negative leukemia cutis., PMID:39888562
Molecular and pharmacological heterogeneity of ETV6::RUNX1 acute lymphoblastic leukemia., PMID:39880832
The role of KLF4 in human primordial germ cell development., PMID:39837498
TP53 mutations are associated with CD19- relapse and inferior outcomes after blinatumomab in adults with ALL., PMID:39820649
Atypical B-Cell Acute Lymphoblastic Leukemia with iAMP21 in the Context of Constitutional Ring Chromosome 21: A Case Report and Review of the Genetic Insights., PMID:39796213
Dual-mode ultrasensitive detection of acute leukemia gene Pax-5a based on smart DNA programmed dendrimer., PMID:39746281
In situ staining with antibodies cross-reactive in pigs, cattle, and white-tailed deer facilitates understanding of biological tissue status and immunopathology., PMID:39719720
Fluorescent biosensor for ultra-stability detection of Pax-5a based on a double cascade amplification strategy., PMID:39709862
Elucidating the molecular and immune interplay between head and neck squamous cell carcinoma and diffuse large B-cell lymphoma through bioinformatics and machine learning., PMID:39697749
Recurrent PAX5::ZCCHC7 rearrangement in B-cell acute lymphoblastic leukemia., PMID:39592470
Copy number alterations in pediatric B-cell precursor acute lymphoblastic leukemia patients and their association with patients' outcome., PMID:39589495
[Childhood acute lymphoblastic leukemia with CREBBP gene mutation: a clinical analysis of 14 cases]., PMID:39587751
Extraosseous Ewing's Sarcoma Masquerading as Adolescent Neck Mass-a Case Report and Review of Literature., PMID:39559010
Emerging roles of long non-coding RNA FOXP4-AS1 in human cancers: From molecular biology to clinical application., PMID:39539976
Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine., PMID:39484404
Targeting DLBCL by mutation-specific disruption of cancer-driving oncogenes., PMID:39469218
Prevalence of the genetic variant rs61330082 and serum levels of the visfatin gene in Mexican individuals with metabolic syndrome: a clinical and bioinformatics approach., PMID:39446118
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5., PMID:39424985
CD36 cell surface expression as a surrogate marker to identify ABL/JAK-class kinase fusions in pediatric BCP-ALL., PMID:39420220
Mycovirus-Containing Aspergillus flavus Alters Transcription Factors in Normal and Acute Lymphoblastic Leukemia Cells., PMID:39408690
Functional variant rs9344 at 11q13.3 regulates CCND1 expression in multiple myeloma with t(11;14)., PMID:39402215
Pax2a, Pax5 and Cdh1-β-catenin, but not Wnt, protect sensory hair cells from destabilizing effects of fgf signaling on cell adhesion., PMID:39332789
Characterisation of cells markers associated with IKZF1plus in BCP-ALL., PMID:39312877
Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5., PMID:39256480
Tviblindi algorithm identifies branching developmental trajectories of human B-cell development and describes abnormalities in RAG-1 and WAS patients., PMID:39235410
Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers., PMID:39183332
Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932
Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia., PMID:39121442
DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma., PMID:39108501
Diagnostic efficacy of SEPT9 and PAX5 gene methylation in gastrointestinal cancer and precancerous lesions., PMID:39097885
PAX5 functions as a tumor suppressor by RB-E2F-mediated cell cycle arrest in Kaposi sarcoma-associated herpesvirus-infected primary effusion lymphoma., PMID:39096792
Unraveling Copy Number Alterations in Pediatric B-Cell Acute Lymphoblastic Leukemia: Correlation with Induction Phase Remission Using MLPA., PMID:39068576
A pre-B acute lymphoblastic leukemia cell line model reveals the mechanism of thalidomide therapy-related B-cell leukemogenesis., PMID:39029626
The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and Other Hematopoietic Cancers., PMID:39017849
The Role of the JAK-STAT Pathway in Childhood B-Cell Acute Lymphoblastic Leukemia., PMID:38999955
MicroRNA-138 promotes the progression of multiple myeloma through targeting paired PAX5., PMID:38959562
For research use only. Not for human or drug use.
