Catalog No.
YHF93201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg343
Predicted molecular weight
40.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02338
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BDH1, 3-hydroxybutyrate dehydrogenase, SDR9C1, Short chain dehydrogenase/reductase family 9C member 1, BDH, D-beta-hydroxybutyrate dehydrogenase, mitochondrial
BDH1 reduces apoptosis and alleviates mitochondrial damage of cardiomyocytes under high glucose condition as a downstream target of miR-125b., PMID:40090116
Pitavastatin and resveratrol bio-nanocomplexes against hyperhomocysteinemia-induced atherosclerosis via blocking ferroptosis-related lipid deposition., PMID:40043912
BDH1 overexpression alleviates diabetic cardiomyopathy through inhibiting H3K9bhb-mediated transcriptional activation of LCN2., PMID:40022118
Interconnections between BDH1-plasma protein-type 2 diabetes Mellitus: a mediated mendelian randomization analysis using plasma proteomics., PMID:39870808
DAG-MAG-ΒHB: A Novel Ketone Diester Modulates NLRP3 Inflammasome Activation in Microglial Cells in Response to Beta-Amyloid and Low Glucose AD-like Conditions., PMID:39796582
Subcellular mass spectrometric detection unveils hyperglycemic memory in the diabetic heart., PMID:39539089
Metabolic engineering of the borneol and camphor degradation pathways in Pseudomonas to produce optically pure bicyclic monoterpenes., PMID:39433004
Preconditioning with β-hydroxybutyrate attenuates lung ischemia-reperfusion injury by suppressing alveolar macrophage pyroptosis through the SIRT1-FOXO3 signaling pathway., PMID:39221615
Protective Effect of Long Noncoding RNA OXCT1-AS1 on Doxorubicin-Induced Apoptosis of Human Myocardial Cells by the Competitive Endogenous RNA Pattern., PMID:38958296
Empagliflozin improves mitochondrial dysfunction in diabetic cardiomyopathy by modulating ketone body metabolism and oxidative stress., PMID:38160540
BDH1-mediated LRRC31 regulation dependent on histone lysine β-hydroxybutyrylation to promote lung adenocarcinoma progression., PMID:38098610
Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models., PMID:38042218
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes., PMID:38040172
BDH1-mediated βOHB metabolism ameliorates diabetic kidney disease by activation of NRF2-mediated antioxidative pathway., PMID:38015723
Liver-Derived Ketogenesis via Overexpressing HMGCS2 Promotes the Recovery of Spinal Cord Injury., PMID:37990936
Identification of mitochondrial related signature associated with immune microenvironment in Alzheimer's disease., PMID:37434203
D-β-Hydroxybutyrate Dehydrogenase Mitigates Diabetes-Induced Atherosclerosis through the Activation of Nrf2., PMID:37399841
Scraping Therapy Improved Muscle Regeneration through Regulating GLUT4/Glycolytic and AMPK/mTOR/4EBP1 Pathways in Rats with Lumbar Multifidus Injury., PMID:37397163
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes., PMID:37026454
BDH1 promotes lung cancer cell proliferation and metastases by PARP1-mediated autophagy., PMID:36919822
BRM Complex in Arabidopsis Adopts ncBAF-like Composition and Requires BRD Subunits for Assembly and Stability., PMID:36835328
The Association of Ketolytic Enzymes Gene Expression Levels with Mitochondrial Activity and Content in Oral Squamous Cell Carcinoma., PMID:36444610
Genome-wide profiling of dysregulated piRNAs and their target genes implicated in oncogenicity of tongue squamous cell carcinoma., PMID:36179965
Enantiopure meso-2,3-butanediol production by metabolically engineered Saccharomyces cerevisiae expressing 2,3-butanediol dehydrogenase from Klebsiella oxytoca., PMID:35644291
Metabolic signatures of pregnancy-induced cardiac growth., PMID:35622533
Protective Roles of Sodium Butyrate in Lipopolysaccharide-Induced Bovine Ruminal Epithelial Cells by Activating G Protein-Coupled Receptors 41., PMID:35600833
Identification of Novel Key Molecular Signatures in the Pathogenesis of Experimental Diabetic Kidney Disease., PMID:35432190
Transcriptome Analysis of Bovine Rumen Tissue in Three Developmental Stages., PMID:35309117
Hypothalamic-pituitary-adrenal axis activation and glucocorticoid-responsive gene expression in skeletal muscle and liver of Apc mice., PMID:35277933
Description of novel variants in consanguineous Pakistani families affected with intellectual disability., PMID:35150401
Expression and clinical significance of BDH1 in liver cancer., PMID:35049211
[Identification and validation of hub genes in prostate cancer progression based on weighted gene co-expression network analysis]., PMID:34916188
Proteomic identification of ruminal epithelial protein expression profiles in response to starter feed supplementation in pre-weaned lambs., PMID:34786500
Hepatocyte-specific fibroblast growth factor 21 overexpression ameliorates high-fat diet-induced obesity and liver steatosis in mice., PMID:34732847
Prostate cancer castrate resistant progression usage of non-canonical androgen receptor signaling and ketone body fuel., PMID:34584218
Differential Response of Hippocampal and Cerebrocortical Autophagy and Ketone Body Metabolism to the Ketogenic Diet., PMID:34456688
MTA2 triggered R-loop trans-regulates BDH1-mediated β-hydroxybutyrylation and potentiates propagation of hepatocellular carcinoma stem cells., PMID:33795651
Protective effect of Ganoderma lucidum spore extract in trimethylamine-N-oxide-induced cardiac dysfunction in rats., PMID:33438268
Effects of a proinflammatory response on metabolic function of cultured, primary ruminal epithelial cells., PMID:33131809
Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization., PMID:32750298
Cloning, expression, identification and characterization of borneol dehydrogenase isozymes in Pseudomonas sp. TCU-HL1., PMID:32738440
Use of gene expression profile to identify potentially relevant transcripts to myofibrillar fragmentation index trait., PMID:32285226
The contribution of ketone bodies to glycolytic inhibition for the treatment of adult and pediatric glioblastoma., PMID:32096068
A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate., PMID:31155495
High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR-γ., PMID:30048968
Skeletal muscle and liver gene expression profiles in finishing steers supplemented with Amaize., PMID:29808540
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development., PMID:29504848
3q29 microduplication syndrome: Description of two new cases and delineation of the minimal critical region., PMID:29501613
Production of (2R, 3R)-2,3-butanediol using engineered Pichia pastoris: strain construction, characterization and fermentation., PMID:29449883
Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure., PMID:29242353