Catalog No.
YHF92001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu403-Asp672
Predicted molecular weight
33.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02156
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PRKCE, PKCE, nPKC-epsilon, Protein kinase C epsilon type
Protein Kinase C Epsilon Overexpression Protects the Heart Against Doxorubicin-Induced Cardiotoxicity Via Activating SIRT1., PMID:40327286
Zapotin mitigates breast cancer progression by targeting PKCε mediated glycolytic pathway regulation., PMID:40296014
Cortical projection neurons with distinct axonal connectivity employ ribosomal complexes with distinct protein compositions., PMID:39763931
Combining metabolomics and network pharmacology to investigate the protective effect of Jiawei Xinglou Chengqi Granules in ischemic stroke., PMID:38958365
Intervention of exogenous VEGF protect brain microvascular endothelial cells from hypoxia-induced injury by regulating PLCγ/RAS/ERK and PI3K/AKT pathways., PMID:38718888
Identification of a novel ALK inhibitor-sensitive PRKCE-ALK gene fusion in lung adenocarcinoma., PMID:38669726
The binding of PKCε and MEG2 to STAT3 regulates IL-6-mediated microglial hyperalgesia during inflammatory pain., PMID:38656553
Brain-specific serine/threonine-protein kinase 1 is a substrate of protein kinase C epsilon involved in sex-specific ethanol and anxiety phenotypes., PMID:38497285
Genetic alterations in the neuronal development genes are associated with changes of the tumor immune microenvironment in pancreatic cancer., PMID:38495381
Paternal preconception alcohol consumption increased Angiotensin II-mediated vasoconstriction in male offspring cerebral arteries via oxidative stress-AT1R pathway., PMID:38488472
PIK3CA regulates development of diabetes retinopathy through the PI3K/Akt/mTOR pathway., PMID:38194422
Integrative analysis of long noncoding RNAs dysregulation and synapse-associated ceRNA regulatory axes in autism., PMID:38057311
Exploring the prognostic significance of PKCε variants in cervical cancer., PMID:37667176
The ε-Isozyme of Protein Kinase C (PKCε) Is Impaired in ALS Motor Cortex and Its Pulse Activation by Bryostatin-1 Produces Long Term Survival in Degenerating SOD1-G93A Motor Neuron-like Cells., PMID:37629005
Multiple suppressing small interfering RNA for cancer treatment-Application to triple-negative breast cancer., PMID:37478121
cAMP-EPAC-PKCε-RIM1α signaling regulates presynaptic long-term potentiation and motor learning., PMID:37159499
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia., PMID:36989375
Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma., PMID:36782184
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation., PMID:36543778
Genome-wide association study and genomic prediction for intramuscular fat content in Suhuai pigs using imputed whole-genome sequencing data., PMID:36540634
Silencing P2X7R Alleviates Diabetic Neuropathic Pain Involving TRPV1 via PKCε/P38MAPK/NF-κB Signaling Pathway in Rats., PMID:36430617
An ErbB Lineage Co-Regulon Harbors Potentially Co-Druggable Targets for Multimodal Precision Therapy in Head and Neck Squamous Cell Carcinoma., PMID:36362284
PRKCE non-coding variants influence on transcription as well as translation of its gene., PMID:36299231
A Novel Cryptic t(2;3)(p21;q25) Translocation Fuses the WWTR1 and PRKCE Genes in Uterine Leiomyoma With 3q- as the Sole Visible Chromosome Abnormality., PMID:35985686
Common and ethnic-specific genetic determinants of hemoglobin concentration between Taiwanese Han Chinese and European Whites: findings from comparative two-stage genome-wide association studies., PMID:35964923
Variants in PRKCE and KLC1, Potential Regulators of Type I Psoriasis., PMID:35800456
Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal-to-zygotic transition in mouse early embryos., PMID:35582855
Multiomics Approach Reveals an Important Role of BNIP3 in Myocardial Remodeling and the Pathogenesis of Heart Failure with Reduced Ejection Fraction., PMID:35563877
Beta-Boswellic Acid Protects Against Cerebral Ischemia/Reperfusion Injury via the Protein Kinase C Epsilon/Nuclear Factor Erythroid 2-like 2/Heme Oxygenase-1 Pathway., PMID:35505050
A transcriptomic analysis based on aberrant methylation levels revealed potential novel therapeutic targets for nasopharyngeal carcinoma., PMID:35282089
Identifying Potential Mitochondrial Proteome Signatures Associated with the Pathogenesis of Pulmonary Arterial Hypertension in the Rat Model., PMID:35237384
Influence of PRKCE non-synonymous variants on protein dynamics and functionality., PMID:35137073
New classification and diagnostic criteria for insulin resistance syndrome., PMID:35110500
Role of aurora kinase B in regulating resistance to paclitaxel in breast cancer cells., PMID:35088239
Mechanism of METTL3-Mediated m6A Modification in Cardiomyocyte Pyroptosis and Myocardial Ischemia-Reperfusion Injury., PMID:35066738
Insights into the potential of withanolides as Phosphodiesterase-4 (PDE4D) inhibitors., PMID:35060432
Competing endogenous RNA network mediated by circ_3205 in SARS-CoV-2 infected cells., PMID:35039944
Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice., PMID:34944441
A Random Walk-Based Method to Identify Candidate Genes Associated With Lymphoma., PMID:34899868
Systems biology and machine learning approaches identify drug targets in diabetic nephropathy., PMID:34873190
A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division., PMID:34836941
Aberrant expression of SNHG12 contributes to N, N-dimethylformamide-induced hepatic apoptosis both in short-term and long-term DMF exposure., PMID:34733487
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma., PMID:34720024
PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode., PMID:34147527
Genome-wide DNA methylation profiling in nonalcoholic fatty liver reveals predictive aberrant methylation in PRKCE and SEC14L3 promoters., PMID:34108094
Hippocampal Subregion and Gene Detection in Alzheimer's Disease Based on Genetic Clustering Random Forest., PMID:34062866
Proteomic and phosphoproteomic profiling of shammah induced signaling in oral keratinocytes., PMID:33931671
Identification of genetic mutations related to invasion and metastasis of acral melanoma via whole-exome sequencing., PMID:33890690
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1., PMID:33484341
PKCε associates with the Kv3.4 channel to promote its expression in a kinase activity-dependent manner., PMID:33368632
For research use only. Not for human or drug use.
