Catalog No.
YHF87701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His903-Val1121
Predicted molecular weight
26.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01538
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYT1, Myelin transcription factor 1, KIAA0835, MTF1, MyT1, KIAA1050, Proteolipid protein-binding protein, Myelin transcription factor I, MyTI, PLPB1, MYTI
A Positive Feedback DNA-PK/MYT1L-CXCR1-ERK1/2 Proliferative Signaling Loop in Glioblastoma., PMID:40362634
Editing the growth differentiation factor 9 gene affects porcine oocytes in vitro maturation by inactivating the maturation promoting factor., PMID:39933265
Myt1 Kinase: An Emerging Cell-Cycle Regulator for Cancer Therapeutics., PMID:39821288
N-Glycoside of Indolo[2,3-a]pyrrolo[3,4-c]carbazole LCS1269 Exerts Anti-Glioblastoma Effects by G2 Cell Cycle Arrest and CDK1 Activity Modulation: Molecular Docking Studies, Biological Investigations, and ADMET Prediction., PMID:39770484
Myelin Transcription Factor 1 (MyT1) overexpression mitigates social isolation-induced behavioral deficits: Insights into cortical synaptotagmin 1 regulation and antidepressant-like effects., PMID:39592028
Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis., PMID:39395799
BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis., PMID:39319704
Metabolic Stress Levels Influence the Ability of Myelin Transcription Factors to Regulate β-Cell Identity and Survival., PMID:39058602
Fine mapping of candidate effector genes for heart rate., PMID:38969939
PEMF Potentiates Doxorubicin-induced Late G2 Arrest in MDA-MB-231 Breast Cancer Cells., PMID:38925852
C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals., PMID:38869949
Synaptotagmins family affect glucose transport in retinal pigment epithelial cells through their ubiquitination-mediated degradation and glucose transporter-1 regulation., PMID:38766439
Asynchronous microexon splicing of LSD1 and PHF21A during neurodevelopment., PMID:38562691
Myt1 kinase inhibitors - Insight into structural features, offering potential frameworks., PMID:38331334
Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer., PMID:38146659
Arf1 GTPase Regulates Golgi-Dependent G2/M Transition and Spindle Organization in Oocyte Meiosis., PMID:38014604
Cancer-Associated Fibroblasts Influence Survival in Pleural Mesothelioma: Digital Gene Expression Analysis and Supervised Machine Learning Model., PMID:37569808
CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the Timing of Mitotic Entry and Progression., PMID:37372141
The Effective Analysis for Blue Honeysuckle Extract in the Treatment of Hepatocellular Carcinoma., PMID:36212967
Targeting replication stress in cancer therapy., PMID:36202931
Expression of myelin transcription factor 1 and lamin B receptor mediate neural progenitor fate transition in the zebrafish spinal cord pMN domain., PMID:36063998
Revisiting the multisite phosphorylation that produces the M-phase supershift of key mitotic regulators., PMID:35976701
Regulation of oocyte maturation: Role of conserved ERK signaling., PMID:35908193
Cytosolic Nuclear Sensor Dhx9 Controls Medullary Thymic Epithelial Cell Differentiation by p53-Mediated Pathways., PMID:35720303
Tracing the origins of glioblastoma by investigating the role of gliogenic and related neurogenic genes/signaling pathways in GBM development: a systematic review., PMID:35538578
Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress., PMID:35292537
CDC25B is required for the metaphase I-metaphase II transition in mouse oocytes., PMID:35237831
Association between serum miRNAs and gingival gene expression in an obese rat model., PMID:35234284
Compartmentalized control of Cdk1 drives mitotic spindle assembly., PMID:35081344
Regulation of Myt1 kinase activity via its N-terminal region in Xenopus meiosis and mitosis., PMID:34695617
Genistein-induced Anticancer Effects on Acute Leukemia Cells Involve the Regulation of Wnt Signaling Pathway Through H4K20me1 Rather Than DNA Demethylation., PMID:34669117
CDC2 Is an Important Driver of Vascular Smooth Muscle Cell Proliferation via FOXM1 and PLK1 in Pulmonary Arterial Hypertension., PMID:34203295
Inactivation of the Akt/FOXM1 Signaling Pathway by Panobinostat Suppresses the Proliferation and Metastasis of Gastric Cancer Cells., PMID:34073071
Dysregulation of Myt1 expression acts as a potential peripheral biomarker for major depressive disorder and bipolar disorder., PMID:34011236
Novel MYT1 variants expose the complexity of oculo-auriculo-vertebral spectrum genetic mechanisms., PMID:33880880
Bioinformatics analysis of Myelin Transcription Factor 1., PMID:33682781
Interactions between the WEE-1.3 kinase and the PAM-1 aminopeptidase in oocyte maturation and the early C. elegans embryo., PMID:33681968
Molecular Mechanisms Underlying Ascl1-Mediated Astrocyte-to-Neuron Conversion., PMID:33577795
Homoharringtonine inhibits melanoma cells proliferation in vitro and vivo by inducing DNA damage, apoptosis, and G2/M cell cycle arrest., PMID:33548212
Genome-Wide DNA Methylation Analysis of a Cohort of 41 Patients Affected by Oculo-Auriculo-Vertebral Spectrum (OAVS)., PMID:33530447
Nestorone® , a 19nor-progesterone derivative boosts remyelination in an animal model of demyelination., PMID:33369182
Myt1 Kinase Couples Mitotic Cell Cycle Exit with Differentiation in Drosophila., PMID:33207203
ZNF300 promotes chemoresistance and aggressive behaviour in non-small-cell lung cancer., PMID:33078469
ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the MYT1-Egln3-Sirt1 Axis., PMID:33038325
MYT1 role in the microtia-craniofacial microsomia spectrum., PMID:32871052
The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation., PMID:32668239
The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review., PMID:32518522
Oligodendrocyte pathology exceeds axonal pathology in white matter in human amyotrophic lateral sclerosis., PMID:32391572
Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival., PMID:32359405
MYT1 attenuates neuroblastoma cell differentiation by interacting with the LSD1/CoREST complex., PMID:32251364
For research use only. Not for human or drug use.
