Catalog No.
YHF83501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala98-Gln355
Predicted molecular weight
30.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q00796
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
(R,R)-butanediol dehydrogenase, RDH, Polyol dehydrogenase, Sorbitol dehydrogenase, Ribitol dehydrogenase, SORD, Xylitol dehydrogenase, XDH, L-iditol 2-dehydrogenase, SDH
Identification of Shared Pathways and Molecules Between Type 2 Diabetes and Lung Adenocarcinoma and the Impact of High Glucose Environment on Lung Adenocarcinoma., PMID:40212965
Structural and Mechanistic Characterization of the Flavin-Dependent Monooxygenase and Oxidase Involved in Sorbicillinoid Biosynthesis., PMID:40052414
Genetic association of MIR-449B, GCLC, eNOS, SORD, and ENPP1 with diabetic retinopathy., PMID:39952424
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer., PMID:39567724
The splicing factor SF3B1 is essential for proper alternative splicing and zygotic genome activation in early porcine embryos., PMID:39521214
Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures., PMID:39126371
Proteomic analysis of Rana sylvatica reveals differentially expressed proteins in liver in response to anoxia, dehydration or freezing stress., PMID:38965296
Metabolic pathways for glucose and fructose: I synthesis and metabolism of fructose by ovine conceptuses†., PMID:38501845
Skeletal muscle involvement in biallelic SORD mutations: case report and review of the literature., PMID:38406380
Gene therapy and other novel treatment approaches for Charcot-Marie-Tooth disease., PMID:37455204
Identification of Potential Biomarkers for Coronary Artery Disease Based on Cuproptosis., PMID:36743388
Cross-Talk between Transcriptome Analysis and Dynamic Changes of Carbohydrates Identifies Stage-Specific Genes during the Flower Bud Differentiation Process of Chinese Cherry (Prunus pseudocerasus L.)., PMID:36555203
Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression., PMID:36244575
[Genetic distribution in Chinese patients with hereditary peripheral neuropathy]., PMID:36241230
Association of SORD mutation with autosomal recessive asymmetric distal hereditary motor neuropathy., PMID:35436891
UDP-glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in breast mesenchymal cell lines., PMID:34942055
Tanshinone IIA suppresses the progression of lung adenocarcinoma through regulating CCNA2-CDK2 complex and AURKA/PLK1 pathway., PMID:34880385
Challenges in Treating Charcot-Marie-Tooth Disease and Related Neuropathies: Current Management and Future Perspectives., PMID:34827446
Metabolic Processes are Potential Biological Processes Distinguishing Nonischemic Dilated Cardiomyopathy from Ischemic Cardiomyopathy: A Clue from Serum Proteomics., PMID:34557019
Systems Biomedicine of Primary and Metastatic Colorectal Cancer Reveals Potential Therapeutic Targets., PMID:34249670
Use of Network Pharmacology to Explore the Mechanism of Gegen (Puerariae lobatae Radix) in the Treatment of Type 2 Diabetes Mellitus Associated with Hyperlipidemia., PMID:33953784
Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism., PMID:33933676
Identification of coding region SNPs from specific and sensitive mRNA biomarkers for the deconvolution of the semen donor in a body fluid mixture., PMID:33610949
Biallelic SORD pathogenic variants cause Chinese patients with distal hereditary motor neuropathy., PMID:33397963
Distal hereditary motor neuropathies: Mutation spectrum and genotype-phenotype correlation., PMID:33369814
Fructose Metabolism in Cancer., PMID:33302403
The same but different: multiple functions of the fungal flavin dependent monooxygenase SorD from Penicillium chrysogenum., PMID:32789380
Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes., PMID:32367058
Diels-Alder Reactions During the Biosynthesis of Sorbicillinoids., PMID:31943627
Unexpected roles for ADH1 and SORD in catalyzing the final step of erythritol biosynthesis., PMID:31511322
Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining., PMID:31231467
Transcriptome analysis of three cultivars of Poria cocos reveals genes related to the biosynthesis of polysaccharides., PMID:30010416
A hnRNP K⁻AR-Related Signature Reflects Progression toward Castration-Resistant Prostate Cancer., PMID:29966326
Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells., PMID:29343522
Effect of siRNA-mediated gene silencing of transketolase on A549 lung cancer cells., PMID:29113225
Alterations in epididymal proteomics and antioxidant activity of mice exposed to fluoride., PMID:28918527
Mechanism and regulation of sorbicillin biosynthesis by Penicillium chrysogenum., PMID:28618182
Impact of male fertility status on the transcriptome of the bovine epididymis., PMID:28379507
Comparative proteomic analysis of liver antioxidant mechanisms in Megalobrama amblycephala stimulated with dietary emodin., PMID:28084435
Targeted Proteomics for Multiplexed Verification of Markers of Colorectal Tumorigenesis., PMID:28062797
Ancestry-based stratified analysis of Immunochip data identifies novel associations with celiac disease., PMID:27650971
Fructose Synthesis and Transport at the Uterine-Placental Interface of Pigs: Cell-Specific Localization of SLC2A5, SLC2A8, and Components of the Polyol Pathway., PMID:27535960
Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa., PMID:26647419
Proteomics of human aqueous humor., PMID:25933257
A competitive chemical-proteomic platform to identify zinc-binding cysteines., PMID:24111988
Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians., PMID:23850972
Malignant pleural effusion cells show aberrant glucose metabolism gene expression., PMID:20884743
Sorbitol dehydrogenase expression is regulated by androgens in the human prostate., PMID:20372835
Analysis of proteomic changes associated with sperm capacitation through the combined use of IPG-strip pre-fractionation followed by RP chromatography LC-MS/MS analysis., PMID:19943266
Neuroimaging of the vesicular acetylcholine transporter by a novel 4-[18F]fluoro-benzoyl derivative of 7-hydroxy-6-(4-phenyl-piperidin-1-yl)-octahydro-benzo[1,4]oxazines., PMID:19181265
For research use only. Not for human or drug use.
