Catalog No.
YHF83001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val15-Pro288
Predicted molecular weight
32.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q00613
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Heat shock factor protein 1, HSF 1, HSTF 1, HSF1, HSTF1, Heat shock transcription factor 1
Interaction between Maslinic acid and HSF1 enhances the ubiquitin degradation of HSF1, resulting in the inhibitory effect of pancreatic cancer., PMID:40504349
Transcription and functional analysis of phosphine fumigation regulating heat responses in Bactrocera dorsalis., PMID:40500047
Advanced Paternal Age and Sperm Proteome Dynamics: A Possible Explanation for Age-Associated Male Fertility Decline., PMID:40497989
Undescribed Phenylpropanoid-Substituted Ester-Type Catechins from Green Tea Exert Antiaging Effects in Caenorhabditis elegans via Activating DAF-16, HSF-1, and Heat Shock Proteins., PMID:40497548
HSF1 remodels mitochondrial biogenesis and function in cancer cells via TIMM17A., PMID:40463013
A guide to heat shock factors as multifunctional transcriptional regulators., PMID:40457168
Cannabidiol ameliorates seizures and neuronal damage in ferric chloride-induced posttraumatic epilepsy by targeting TRPV1 channel., PMID:40449694
Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid., PMID:40445107
De novo assembly of nuclear stress bodies rearranges and enhances NFIL3 to restrain acute inflammatory responses., PMID:40436014
125I inhibits the progression of cervical cancer by upregulating the HSF1/PU.1/SYK signaling pathway and consequently enhancing the apoptotic response mediated by ROS/USP7/P53., PMID:40399470
Pharmacological Regulation of Heat Shock Response via Aptamer-Antidote Couple., PMID:40388587
Inhibition of SIRT1/HSF1 pathway contributes to doxorubicin-induced nephrotoxicity in ovarian tumor-bearing mice., PMID:40347321
Neurogrit Gold Attenuates 6-OHDA-Induced Dopaminergic Neurodegeneration in Parkinson's Model of Caenorhabditis elegans by Reducing α-Synuclein Accumulation and Pink/Pdr-1 Driven Mitochondrial Dysfunction., PMID:40342222
Identifying Genes Associated with the Anticancer Activity of a Fluorinated Chalcone in Triple-Negative Breast Cancer Cells Using Bioinformatics Tools., PMID:40332279
HDAC1 is involved in the destabilization of the HSF2 protein under nonstress and stress conditions., PMID:40318841
Targeting prominin-2/BACH1/GLS pathway to inhibit oxidative stress-induced ferroptosis of bone mesenchymal stem cells., PMID:40301995
HSP70 Modulators for the Correction of Cognitive, Mnemonic, and Behavioral Disorders After Prenatal Hypoxia., PMID:40299680
Signaling mechanisms and cis -regulatory control of Samd14 in erythroid regeneration., PMID:40293138
Role of HSF1 in cell division, tumorigenesis and therapy: a literature review., PMID:40287736
KRIBB11 Exerts Anticancer Effects on A172 Glioblastoma Cells via the Cdh1/SKP2/p27 and HSF1/p53/p21 Pathways., PMID:40280718
Transposable Elements Drive Regulatory and Functional Innovation of F-box Genes., PMID:40279373
Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques., PMID:40266253
E3 ubiquitin ligase CHIP alleviates H/R-induced myocardial injury by inhibiting pyroptosis., PMID:40259143
Identification of SURF4 and RALGAPA1 as promising therapeutic targets in glioblastoma and pan-cancer through integrative multi-omics, CRISPR-Cas9 screening and prognostic meta-analysis., PMID:40249536
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences., PMID:40243484
Identification of novel small molecule chaperone activators for neurodegenerative disease treatment., PMID:40239269
Knockdown of HSF1 inhibits invasion, metastasis, and proliferation of endometrial carcinoma cells while promoting apoptosis., PMID:40235068
Sake lees extract obtained using a novel continuous phase-transition extraction method: evaluation of its bioactive composition, anti-aging efficacy and mechanism., PMID:40227670
Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition., PMID:40204953
Elevated expression of HSF1 promotes the progression of colorectal cancer by activating CLDN3 transcription., PMID:40162508
The special phenotypic characteristics of Dummerstorf superfertile mouse lines could depend on the expression levels of IGF-axis genes., PMID:40158446
Amyloidogenesis promotes HSF1 activity enhancing cell survival during breast cancer metastatic colonization., PMID:40147541
Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo., PMID:40147538
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis., PMID:40133683
Aqueous extracts and protein concentrate of Tenebrio molitor prolong the lifespan of Caenorhabditis elegans under environmental stress conditions., PMID:40125790
Targeting HSF1-TLR9 Axis: Celastrol as a Potential Therapeutic for Liver Injury in Traumatic Hemorrhagic Shock., PMID:40116098
Dynamic regulation of murine RNA polymerase III transcription during heat shock stress., PMID:40101151
Dietary alpha-lipoic acid alleviates heat stress by modulating insulin-like signaling to maintain homeostasis in C. elegans., PMID:40095598
Dried plum supplementation enhanced the expression of liver antioxidant capacity, metabolism, and epigenetic-related gene markers in broiler chickens under heat stress conditions: Dried plum increased liver metabolism in broiler., PMID:40054117
Synergistic effects of 6-shogaol and hyperthermia on ACHN renal cancer cells: modulation of ROS and heat shock pro-teins in cancer therapy., PMID:40051570
Supramolecular nanoagent as a dual-blocked thermoresistance inhibitor for effective mild-temperature photothermal therapy., PMID:40049045
Mechanistic Insights Into Oxidative Response of Heat Shock Factor 1 Condensates., PMID:40017748
IER5 Promotes Ovarian Cancer Cell Proliferation and Peritoneal Dissemination., PMID:40002205
HSF1 Mediates Palmitic Acid-Disrupted Lipid Metabolism and Inflammatory Response by Maintaining Endoplasmic Reticulum Homeostasis in Fish., PMID:39987503
Absence of hippocampal pathology persists in the Q175DN mouse model of Huntington's disease despite elevated HTT aggregation., PMID:39973391
The α-MG exhibits neuroprotective potential by reducing amyloid beta peptide-induced inflammation, oxidative stress, and tau aggregation in human neural stem cells., PMID:39954799
The anti-aging and anti-Alzheimer's disease potential of kinsenoside prepared from Anoectochilus roxburghii., PMID:39938659
Dynamic Chromatin Accessibility and Transcriptional Regulation in the Eyes of Red Tilapia (Oreochromis sp.) in Response to Wintering Stress., PMID:39937323
HSF1 and CPSF1 affect milk fat and protein synthesis by regulating the AKT/mTOR signaling pathway., PMID:39932399
Characterization of a heat shock factor 1 (HSF1) gene and the association of its single nucleotide polymorphisms with susceptibility/resistance of Magallana gigas to Halomonas sp. 7T., PMID:39894093
For research use only. Not for human or drug use.
