Catalog No.
YHF80501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro70
Predicted molecular weight
34.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P98194
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Calcium-transporting ATPase type 2C member 1, ATP-dependent Ca(2+) pump PMR1, PMR1L, KIAA1347, ATP2C1, ATPase 2C1
Tofacitinib as a promising treatment for refractory erythroderma-like Hailey-Hailey disease., PMID:40298163
Targeting the secretory program of 3q-amplified lung cancers., PMID:40047887
Chemigenetic Ca2+ indicators report elevated Ca2+ levels in endothelial Weibel-Palade bodies., PMID:39869616
Hailey-Hailey disease successfully treated with naloxone: 2 case reports and Review of the literature on efficacy of opioid receptor antagonist in Hailey-Hailey disease patients., PMID:39842790
Hailey-Hailey Disease Caused by a Novel Deep Intronic Variant in ATP2C1., PMID:39523677
Adipocytes reprogram the proteome of breast cancer cells in organotypic three-dimensional cell cultures., PMID:39505903
Biochemical and molecular responses to long-term salinity challenges in northern quahogs Mercenaria mercenaria., PMID:39250983
Increased risk of cardiac arrhythmia in Hailey-Hailey disease patients., PMID:39241028
Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study., PMID:39217398
Pumping the Breaks on Acantholytic Skin Disorders: Targeting Calcium Pumps, Desmosomes, and Downstream Signaling in Darier, Hailey-Hailey, and Grover Disease., PMID:39207315
Generalized Hailey-Hailey disease associated with c.2395C>T ATP2C1 gene mutation and fatal outcome., PMID:38959923
ATP2C1 knockdown induces abnormal expressions of cytoskeletal and tight junction proteins mimicking Hailey-Hailey disease., PMID:38841932
Hailey-Hailey disease: clinical, diagnostic and therapeutic update., PMID:38789364
A case of Hailey-Hailey disease with novel ATP2C1 gene variant (c.G925C) showing unusual phenotype., PMID:38711270
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer., PMID:38662435
A novel ATP2C1 mutation (c.1840-1G>A) in a sporadic case of isolated perianal Hailey-Hailey disease with human papillomavirus type 58 infection., PMID:38637183
Frequency of the p.Thr241Asn mutation in Chinese patients with congenital factor VII deficiency., PMID:38335567
Two patients with Hailey-Hailey disease with novel pathogenic ATP2C1 variants suggesting possible genotype/phenotype correlations., PMID:38111361
Hailey-Hailey Disease is Associated with Diabetes: A Population-based Cohort Study, Clinical Cohort Study, and Pedigree Analysis., PMID:38014829
[Establishment of a prostate cancer prognostic risk model based on the TCGA database and inflammation-related genes]., PMID:37846114
Hailey-Hailey disease successfully treated with photodynamic therapy: Case report., PMID:37558191
Tetramethylpyrazine ameliorates endotoxin-induced acute lung injury by relieving Golgi stress via the Nrf2/HO-1 signaling pathway., PMID:37550659
Ultrashort wave alleviates oxygen-glucose deprivation/reoxygenation injury via up-regulation of SPCA1 expression in N2a cells., PMID:37539566
Two Novel and a Recurrent ATP2C1 Mutations in Chinese Population with Hailey-Hailey Disease., PMID:37342538
ZNF384-Related Fusion Genes in Acute Lymphoblastic Leukemia., PMID:37306722
Two sporadic cases of childhood-onset Hailey-Hailey disease with superimposed mosaicism., PMID:36922631
Cryo-EM structures of human SPCA1a reveal the mechanism of Ca2+/Mn2+ transport into the Golgi apparatus., PMID:36867705
Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey-Hailey disease., PMID:36789506
GARP dysfunction results in COPI displacement, depletion of Golgi v-SNAREs and calcium homeostasis proteins., PMID:36578782
Subcellular compartmentalization of STIM1 for the distinction of Darier disease from Hailey-Hailey disease., PMID:36442136
Anti-desmoglein 1 antibody-positive mother and antibody-negative child with Darier's disease., PMID:36074695
Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells., PMID:35787370
Two novel mutations in the ATP2C1 gene found in Japanese patients with Hailey-Hailey disease., PMID:35274376
Two cases of Hailey-Hailey disease effectively treated with apremilast and a review of reported cases., PMID:34569085
Role of pro-inflammatory cytokines in the pathophysiology of herpes simplex virus superinfection in Darier's disease., PMID:34355821
Weak immunohistochemical expression of galectin-3 near blisters in Hailey-Hailey disease., PMID:34272745
Identification of novel potential interaction partners of UDP-galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters., PMID:34242836
Papular acantholytic dyskeratosis of the anogenital area with novel ATP2C1 gene mutations., PMID:34134127
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain., PMID:33926923
Whole exome sequencing improves mutation detection in Hailey-Hailey disease., PMID:33878236
Crosstalk among Calcium ATPases: PMCA, SERCA and SPCA in Mental Diseases., PMID:33801794
A novel deletion mutation in the ATP2C1 gene in a case of generalized Hailey-Hailey disease possibly aggravated by scabies infection., PMID:33580912
Elderly-onset type 1 mosaic form of Hailey-Hailey disease with a postzygotic variant in ATP2C1., PMID:33569803
Generalized Hailey-Hailey disease: Novel splice-site mutations of ATP2C1 gene in Chinese population and a literature review., PMID:33345454
Novel ATP2C1 frame-shift mutation in a mild case of early onset sporadic Hailey-Hailey disease., PMID:33161602
A Novel Microduplication Spanning Exons 8-16 of ATP2C1 That Was Undetectable by Standard Sanger Sequencing in a Japanese Patient With Hailey-Hailey Disease., PMID:33015087
The Golgi Calcium ATPase Pump Plays an Essential Role in Adeno-associated Virus Trafficking and Transduction., PMID:32817219
Identification of ATP2C1 mutations in the patients of Hailey-Hailey disease., PMID:32487029
Novel missense mutation (A414P) in ATP2C1 in a case of familial Hailey-Hailey disease., PMID:32483844
Hailey-Hailey disease with a novel variant, c.1978dupG, in the ATP2C1 gene., PMID:32441372
For research use only. Not for human or drug use.
