Catalog No.
YHF79001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu4149-Ser4391
Predicted molecular weight
27.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P98160
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSPG2, Perlecan, Basement membrane-specific heparan sulfate proteoglycan core protein, HSPG, PLC
The glycosaminoglycan chains of perlecan regulate the perivascular fluid transport., PMID:40340918
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice., PMID:40320111
Comprehensive analysis of blood proteome response to necrotic enteritis in broiler chicken., PMID:40275387
Host transcriptome response to Mycoplasma bovis and bovine viral diarrhea virus in bovine tissues., PMID:40211134
Identification of Biomarkers for Meat Quality in Sichuan Goats Through 4D Label-Free Quantitative Proteomics., PMID:40150416
Distinct role of perlecan in mesenchymal tissue regeneration via genetic and epigenetic modification., PMID:40124846
Trichomonas vaginalis adhesion protein 33 (TvAP33) promotes HPV infection by upregulating the expression of HPV membrane receptor molecules., PMID:40057257
Integrated Approach for Biomarker Discovery and Mechanistic Insights into the Co-Pathogenesis of Type 2 Diabetes Mellitus and Non-Hodgkin Lymphoma., PMID:39906693
Adult human heart extracellular matrix improves human iPSC-CM function via mitochondrial and metabolic maturation., PMID:39862185
Sphingosine-1-Phosphate, a Marker of Endothelial Injury and Disease Severity in Preeclampsia., PMID:39840434
Whole exome sequencing reveals heparan sulfate proteoglycan 2 (HSPG2) as a potential causative gene for kidney stone disease in a Thai family., PMID:39680213
Meta-analysis of proteomics data from osteoblasts, bone, and blood: Insights into druggable targets, active factors, and potential biomarkers for bone biomaterial design., PMID:39620099
Identification of metabolic reprogramming-related genes as potential diagnostic biomarkers for diabetic nephropathy based on bioinformatics., PMID:39609849
Excess Weight Impairs Oocyte Quality, as Reflected by mtDNA and BMP-15., PMID:39594620
Analysis of candidate variants in a Chinese family with monozygotic twins with keratoconus: a case report., PMID:39544142
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin., PMID:39522978
Proteomic Profiling of Endothelial Cell Secretomes After Exposure to Calciprotein Particles Reveals Downregulation of Basement Membrane Assembly and Increased Release of Soluble CD59., PMID:39518935
Insoluble proteomics analysis of acute intracranial large vessel occlusive thrombus., PMID:39454879
Single-Cell Meta-Analysis Uncovers the Pancreatic Endothelial Cell Transcriptomic Signature and Reveals a Key Role for NKX2-3 in PLVAP Expression., PMID:39445426
Identification of HSPG2 as a bladder pro-tumor protein through NID1/AKT signaling., PMID:39438949
Hepatitis B Virus X Protein Contributes to Hepatocellular Carcinoma via Upregulation of KIAA1429 Methyltransferase and mRNA m6A Hypermethylation of HSPG2/Perlecan., PMID:39412412
Unconventional p65/p52 NF-κB module regulates key tumor microenvironment-related genes in breast tumor-associated macrophages (TAMs)., PMID:39278618
Expanding genetic and clinical aspects of Schwartz-Jampel syndrome: A report of two cases with literature review., PMID:39157536
The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells., PMID:39149513
Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc., PMID:39081381
Extracellular Matrix Protein Signatures of the Outer and Inner Zones of the Rat Adrenal Cortex., PMID:39018382
Whole-exome sequencing screening for candidate genes and variants associated with primary sporadic keratoconus in Chinese patients., PMID:38908538
FOXO3 suppresses lymphoma progression through promoting miR-34b/HSPG2 axis., PMID:38775786
The interaction of endorepellin and neurexin triggers neuroepithelial autophagy and maintains neural tube development., PMID:38702277
Analyses of lncRNA and mRNA profiles in recurrent atrial fibrillation after catheter ablation., PMID:38643140
Cellular and Transcriptional Response of Human Astrocytes to Hybrid Protein Materials., PMID:38632900
Proteomic and metabolomic characterization of bone, liver, and lung metastases in plasma of breast cancer patients., PMID:38571380
Proteomics analysis of differentially abundant proteins in the rohu kidney infected with Edwardsiella tarda., PMID:38430708
Dyssegmental dysplasia Rolland-Desbuquois type is caused by pathogenic variants in HSPG2 - a founder haplotype shared in five patients., PMID:38424183
Genome-wide association study identifies genetic variants underlying footrot in Portuguese Merino sheep., PMID:38262937
Different Transcriptome Features of Peripheral Blood Mononuclear Cells in Non-Emphysematous Chronic Obstructive Pulmonary Disease., PMID:38203236
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes., PMID:38198277
A comprehensive proteomic profiling of urinary exosomes and the identification of early non-invasive biomarker in patients with coronary artery disease., PMID:38151158
Prolonged use of temozolomide leads to increased anxiety and decreased content of aggrecan and chondroitin sulfate in brain tissues of aged rats., PMID:38124768
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway., PMID:38046235
Integrated bioinformatics approaches to investigate alterations in transcriptomic profiles of monkeypox infected human cell line model., PMID:37992435
CDK5R1, GSE1, HSPG2 and WDFY3 as indirect epigenetic-sensitive genes in atrial fibrillation., PMID:37991085
[The Schwartz-Jampel syndrome]., PMID:37975769
Methyl donor diet attenuates intimal hyperplasia after vascular injury in rats., PMID:37844765
Dynamic alterations of the transcriptome-wide m6A methylome in cytogenetically normal acute myeloid leukaemia during initial diagnosis and relapse., PMID:37820824
Novel HSPG2 Gene Mutation Causing Schwartz-Jampel Syndrome in a Moroccan Family: A Literature Review., PMID:37761893
Untying the Gordian knot of composite hemangioendothelioma: Discovery of novel fusions., PMID:37658696
A precise design strategy for a cell-derived extracellular matrix based on CRISPR/Cas9 for regulating neural stem cell function., PMID:37593879
Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models., PMID:37582915
Identification of B-cell-related HSPG2 and CDSN as susceptibility loci for Kawasaki disease., PMID:37453912
For research use only. Not for human or drug use.
