Catalog No.
YHF78601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr5568-His5654
Predicted molecular weight
21.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P98088
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mucin-5 subtype AC, tracheobronchial, Gastric mucin, Mucin-5AC, TBM, MUC-5AC, Tracheobronchial mucin, Major airway glycoprotein, MUC5AC, MUC5
Dynamics of Bacteria-Mucus Interactions: Quantitative Assessment of MUC5AC and Helicobacter pylori Adhesion to the Gastric Tissue on the Model of Cavia porcellus., PMID:40498303
Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs., PMID:40496925
1-O-Acetylbritannilactone exerts anti-inflammatory and anti-MUC5AC effects by targeting PKC-α and downregulating the SRC/EGFR/MAPK signaling pathway., PMID:40480001
Investigation of competitive binding of the essential trace elements zinc, iron, copper and manganese by gastrointestinal mucins and the effect on their absorption in vitro., PMID:40472908
Clinicopathological features and mucin expression of early papillary gastric adenocarcinoma., PMID:40467732
mTOR signaling regulates the development of airway mucous cell metaplasia associated with severe asthma., PMID:40446022
The role of CDX2, MUC5AC, and p53 in the evaluation of the progression of serrated lesions toward colorectal carcinoma., PMID:40384196
ST6GalNAc-I regulates tumor cell sialylation via NECTIN2/MUC5AC-mediated immunosuppression and angiogenesis in non-small cell lung cancer., PMID:40371640
Rebamipide Enhances Pathogen Defense and Mitigates Inflammation in a Particulate Matter-Induced Ocular Surface Inflammation Rat Model., PMID:40332777
Morus alba L.-Glycyrrhiza uralensis alleviate chronic obstructive pulmonary disease by inhibiting the arachidonic acid metabolism pathway., PMID:40324701
Cigarette smoke induces endoplasmic reticulum stress-associated mucus hypersecretion via orosomucoid 1-like protein 3 in airway epithelia., PMID:40317248
Identification and validation of differentially expressed genes in allergic asthma pathogenesis using whole-transcriptome sequencing., PMID:40309741
Mucins and Their Roles in Asthma., PMID:40305069
Beta-Sitosterol-Conjugated Sinapic Acid-Engineered Nanoliposome: Biomucoadhesive and Enzyme-Responsive Targeted Oral Therapy in Ulcerative Colitis., PMID:40298241
Hederacoside C Modulates EGF-Induced MUC5AC Mucin Gene Expression by Regulating the MAPK Signaling Pathway in Human Airway Epithelial Cells., PMID:40275567
Comprehensive single-cell RNA-sequencing study of Tollip deficiency effect in IL-13-stimulated human airway epithelial cells., PMID:40269942
Solasodine inhibits the Th2 immune response and airway remodeling in asthmatic mice through the Runx3/NLRP3 pathway., PMID:40268171
Exploring the optimal timing of HanChuan Zupa Granule for asthma treatment using a comprehensive research approach of "Disease circadian rhythm-drug target prediction-drug efficacy validation"., PMID:40254112
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation., PMID:40239879
A pilot study of morphological features of the eyelid margin with conjunctival goblet cells and MUC5AC in tear film of dry eye., PMID:40220145
MMP12 deficiency attenuates menthol e-cigarette plus house dust-mite effects on pulmonary iron homeostasis and oxidative stress., PMID:40217328
Identification and Validation of Cyclic Peptides with Mucin-Selective, Location-Specific Binding in the Gastrointestinal Tract., PMID:40216380
Resveratrol inhibits lipopolysaccharide‑induced MUC5AC expression and airway inflammation via MAPK and Nrf2 pathways in human bronchial epithelial cells and an acute inflammatory mouse model., PMID:40211706
Tracking mucosal innate immune responses to three influenza A virus strains in a highly translational pig model using nasopharyngeal swabs., PMID:40165394
AAV-mediated MUC5AC siRNA delivery to prevent mucociliary dysfunction in asthma., PMID:40161599
Breviscapine Attenuates Lipopolysaccharide-Induced Airway Dysfunction in Normal Human Bronchial Epithelial Cells by Suppressing the TLR4/MyD88 Signaling Pathway., PMID:40159917
Clinical efficacy and chemoresistance analysis of precision neoadjuvant chemotherapy for borderline resectable pancreatic cancer: a prospective, single-arm pilot study., PMID:40146255
NOTCH pathway was involved in Kaempferol 3-O-gentiobioside attenuated airway inflammation and mucus hypersecretion., PMID:40140655
Mucin 5AC as a Biomarker for Sessile Serrated Lesions: Results From a Systematic Review and Meta-Analysis., PMID:40110854
An emerging entity of gastric adenocarcinoma: clinicopathological features and differential diagnosis of gastric adenocarcinoma of fundic-gland type in 25 retrospective cases., PMID:40100386
Therapeutic strategies to reverse cigarette smoke-induced ion channel and mucociliary dysfunction in COPD airway epithelial cells., PMID:40095970
Effective-Component Compatibility of Bufei Yishen Formula (ECC-BYF) III Inhibits Mucus Hypersecretion by BEAS-2B Cells via miR-146a-5p-Mediated Regulation of the EGFR/MEK/ERK Pathway., PMID:40092321
Cellular and molecular features of asthma mucus plugs provide clues about their formation and persistence., PMID:40091838
Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers., PMID:40087745
The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo., PMID:40081908
Cellulophaga algicola alginate lyase and Pseudomonas aeruginosa Psl glycoside hydrolase inhibit biofilm formation by Pseudomonas aeruginosa CF2843 on three-dimensional aggregates of lung epithelial cells., PMID:40066315
MUC5AC filaments illuminate the structural diversification of respiratory and intestinal mucins., PMID:40035770
Foreign Mucins Alter the Properties of Reconstituted Gastric Mucus., PMID:40021478
Structure of the MUC5AC VWD3 assembly responsible for the formation of net-like mucin polymers., PMID:40016425
Protective Effects of Atractylodis Rhizoma Extracts on Lung Injury Induced by Particulate Matter 2.5 in Mice., PMID:40002314
Transcriptome analysis reveals modulations in glycosylation profiles of the mucosal barrier and their potential interaction with gut microbiota in weaned piglets., PMID:39990197
Deoxynivalenol modulated mucin expression and proinflammatory cytokine production, affecting susceptibility to enteroinvasive Escherichia coli infection in intestinal epithelial cells., PMID:39980277
Development and qualification of an LC-MS/MS method for quantification of MUC5AC and MUC5B mucins in spontaneous sputum., PMID:39976267
Associations of mucinous differentiation and mucin expression with immune cell infiltration and prognosis in colorectal adenocarcinoma., PMID:39966658
Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease., PMID:39965565
Development and validation of a Guinea pig model for concurrent allergic rhinitis and asthma using recombinant Der f 2., PMID:39953469
Astaxanthin protects against environmentally persistent free radical-induced oxidative stress in well-differentiated respiratory epithelium., PMID:39952200
Multiple metachronous foveolar-type gastric adenomas in a Helicobacter pylori-naïve patient with long-term use of a proton pump inhibitor: a case report., PMID:39939466
A Gallbladder-Specific Hydrophobic Bile Acid-FXR-MUC1 Signaling Axis Mediates Cholesterol Gallstone Formation., PMID:39932450
Anti-Inflammatory Dimeric and Trimeric Flavonoids from the Roots ofPistacia weinmannifolia., PMID:39931765
For research use only. Not for human or drug use.
