Catalog No.
YHF70701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln21-Gly198
Predicted molecular weight
22.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P80188
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lipocalin-2, Neutrophil gelatinase-associated lipocalin, Oncogene 24p3, NGAL, HNL, Siderocalin, LCN2, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, p25
Proteomic profiling reveals immunomodulatory role of IL-33 in ocular bacterial and fungal infections., PMID:40512033
Identification of protein biomarker candidates associated with organ-specific immune-related toxicity and response to management by plasma proteomics., PMID:40510441
The relationship between homocysteine levels and blood pressure variability with early renal injury marker NGAL in patients with H-type hypertension., PMID:40484960
Serum neutrophil gelatinase associated Lipocalin as a novel biomarker for diagnosing acute pyelonephritis in adults., PMID:40467696
Kidney Transcriptomic and Proteomic Analyses Provide New Insight into the Pathogenesis of IgA Nephropathy in Mice., PMID:40461644
High CD36 expression in the tumor microenvironmental vasculature correlates with unfavorable overall survival in high grade serous ovarian cancer., PMID:40456794
Mechanism of Dihydroartemisinin in activating macrophages to enhance host resistance to malaria., PMID:40450979
Special status of iron transfer proteins in the serum of breast cancer patients., PMID:40450119
Alexander's Disease: Potential Drug Targets and Future Directions., PMID:40448810
Antipruritic Effect of 2,3-Dehydrosilybin in Glial Cells and Chloroquine-Treated Mice., PMID:40443235
Urinary NGAL Outperforms 99mTc-MAG3 Renography in Predicting DCD Kidney Graft Function., PMID:40421388
Multi-omics driven biomarker discovery and pathological insights into Pseudomonas aeruginosa pneumonia., PMID:40413399
LL-37 and citrullinated-LL-37 modulate IL-17A/F-mediated responses and selectively suppress Lipocalin-2 in bronchial epithelial cells., PMID:40410820
Atorvastatin Protects Against the Macrophage/Microglia-Related Neuroinflammation via Inhibiting Lipocalin-2 in Mouse Experimental Intracerebral Hemorrhage Model., PMID:40394428
ITE-mediated AhR activation attenuates atherosclerosis by promoting macrophage M2-like polarization through NF-κB/LCN2 pathway suppression., PMID:40389023
Targeting MYOF suppresses pancreatic ductal adenocarcinoma progression by inhibiting ILF3-LCN2 signaling through disrupting OTUB1-mediated deubiquitination of ILF3., PMID:40381229
Astrocytes-derived LCN2 triggers EV-A71-induced muscle soreness via accumulating lactate., PMID:40378229
Lipocalin-2-mediated ferroptosis as a target for protection against light-induced photoreceptor degeneration., PMID:40375133
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion., PMID:40365739
Faecalibacterium prausnitzii prevents age-related heart failure by suppressing ferroptosis in cardiomyocytes through butyrate-mediated LCN2 regulation., PMID:40364435
NFE2L3 regulates inflammation and oxidative stress-related genes in the colon., PMID:40360021
Characterization of Mucosal Immune-Related lncRNAs and mRNAs in a Mouse Model of Allergic Conjunctivitis., PMID:40357374
LCN2 promotes focal adhesion formation and invasion by stimulating c-Src activation., PMID:40356520
Dynamics of antimicrobial proteins' expression and their bactericidal activity in mouse milk., PMID:40345232
FTO facilitates colorectal cancer chemoresistance via regulation of NUPR1-dependent iron homeostasis., PMID:40334546
Endoplasmic Reticulum Stress Drives Neuroinflammation Through Lipocalin 2 Upregulation in Retinal Microglia After Optic Nerve Injury., PMID:40327012
Thymoquinone enhances efficacy of cervical Cancer therapeutic vaccines via modulating CD8+ T cells., PMID:40316484
TGFB1/CXCL5 axis regulation by LCN2 overexpression: a promising strategy to inhibit colorectal cancer metastasis and enhance prognosis., PMID:40313933
Quantification of intra-amniotic inflammation in late preterm prelabour rupture of membranes., PMID:40295647
Performance of Serum Neutrophil-Gelatinase Associated Lipocalin (NGAL) in the Diagnosis of Pregnancy-Related Acute Kidney Injury (PRAKI) in Delta, State Nigeria: A Prospective Study., PMID:40289010
A Potential Link Between Early Onset Reactive Astrogliosis and Adult-Onset Dysfunction of Leptin Signaling in Polyubiquitin Gene Ubb Knockout Mice., PMID:40287809
The Prognostic Role of Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 Expressions in Gastric Carcinomas., PMID:40277747
Identification of pivotal genes and regulatory networks associated with SAH based on multi-omics analysis and machine learning., PMID:40274967
The role and clinical significance of myeloperoxidase (MPO) and TNF-α in prognostic evaluation of T-COPD., PMID:40269819
The Circadian Clock Component REV-ERB Is an Analgesic Target for Cancer-Induced Tactile Pain Hypersensitivity., PMID:40268481
Engineered mesenchymal stromal cells with interleukin-1beta sticky-trap attenuate osteoarthritis in knee joints., PMID:40264709
MVP-LCN2 axis triggers evasion of ferroptosis to drive hepatocarcinogenesis and sorafenib resistance., PMID:40262414
Serum and cord blood neutrophil gelatinase associated lipocalin levels in pregnant women with gestational diabetes mellitus and its association with tumor necrosis factor-alpha: A cross-sectional study from Tripura, India., PMID:40254320
Lipocalin 2 mediates kidney function abnormalities induced by ischemic stroke in mice: Involvement of neural pathways., PMID:40250700
Evaluation of renal function with neutrophil gelatinase-associated lipocalin in patients with ıron deficiency anemia., PMID:40240782
The impact of ischemic reperfusion injury on contralateral kidneys and the determinants of renal prognosis after robot-assisted partial nephrectomy., PMID:40233076
ADAMTS18 deficiency leads to abnormal brain methylation metabolism, dysregulated neuroinflammatory response, and unsound blood-brain barrier structure in mice., PMID:40227359
Microglial Lcn2 knockout enhances chronic intracerebral hemorrhage recovery by restoring myelin and reducing inflammation., PMID:40225581
Lipocalin-2, Matrix Metalloproteinase-9, and MMP-9/NGAL Complex in Upper Aerodigestive Tract Carcinomas: A Pilot Study., PMID:40214460
Lipocalin-2 promotes NSCLC progression by activating the JAK2/STAT3 signaling pathway., PMID:40211270
Host-microbiota interactions in the infant gut revealed by daily faecal sample time series., PMID:40207273
The immunosuppressive role of neutrophils in infectious and oncological conditions: A study of chemokine receptor CXCR3 and human neutrophil lipocalin levels., PMID:40200380
Chitinase 3-like protein 1 deficiency ameliorates drug-induced acute liver injury by inhibition of neutrophil recruitment through lipocalin-2., PMID:40196357
Blocking the LRH-1/LCN2 axis by ML-180, an LRH-1 inverse agonist, ameliorates osteoarthritis via inhibiting the MAPK pathway., PMID:40194607
Mechanism of LCN2 in cerebral ischemia-reperfusion injury., PMID:40182140
For research use only. Not for human or drug use.
