Catalog No.
YHF63401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu20-Val229
Predicted molecular weight
25.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P78310
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Coxsackievirus B-adenovirus receptor, CVB3-binding protein, Coxsackievirus and adenovirus receptor, HCVADR, CXADR, hCAR, CAR
Identification of Novel Protein Biomarkers for Intrahepatic Cholangiocarcinoma by Integrating Human Plasma Proteome with Genome., PMID:40240670
Establishment of a Panel of Human Cell Lines to Identify Cellular Receptors Used by Enteroviruses to Infect Cells., PMID:39940693
The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome., PMID:39790063
Single-cell RNA sequencing identifies CXADR as a fate determinant of the placental exchange surface., PMID:39747179
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Expression and prognosis of DSG-2, CXADR, CD46 in head and neck squamous cell carcinoma., PMID:39173463
Congenital short bowel syndrome: Cases series in the same family and review of literature., PMID:39173431
Proteomic changes of the bovine blood plasma in response to heat stress in a tropically adapted cattle breed., PMID:39149588
TAZ downregulated ANXA1 expression to modulate myeloma cell interactions with bone marrow mesenchymal stromal cells., PMID:39032857
JAML inhibits colorectal carcinogenesis by modulating the tumor immune microenvironment., PMID:38625487
Using genetics and proteomics data to identify proteins causally related to COVID-19, healthspan and lifespan: a Mendelian randomization study., PMID:38575325
JAML promotes the antitumor role of tumor-resident CD8+ T cells by facilitating their innate-like function in human lung cancer., PMID:38570084
Integrative experimental validation of concomitant miRNAs and transcription factors with differentially expressed genes in acute myocardial infarction., PMID:38552938
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche., PMID:38414005
CXADR promote epithelial-mesenchymal transition in endometriosis by modulating AKT/GSK-3β signaling., PMID:38146657
Detection of genomic variations and selection signatures in Wagyu using whole-genome sequencing data., PMID:37792466
CXADR-Like Membrane Protein Regulates Colonic Epithelial Cell Proliferation and Prevents Tumor Growth., PMID:37716376
CAR virus receptor mediates erythroid differentiation and migration and is downregulated in MDS., PMID:37673973
The junctional adhesion molecule-like protein (JAML) is important for the inflammatory response during contact hypersensitivity., PMID:37619972
Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer., PMID:37585503
Proteome-wide copy-number estimation from transcriptomics., PMID:37503057
Disrupted epithelial permeability as a predictor of severe COVID-19 development., PMID:37422701
Cigarette smoke extract impairs gingival epithelial barrier function., PMID:37286570
PTTG1 Enhances Oncolytic Adenovirus 5 Entry into Pancreatic Adenocarcinoma Cells by Increasing CXADR Expression., PMID:37243239
Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma., PMID:36773293
CXADR: From an Essential Structural Component to a Vital Signaling Mediator in Spermatogenesis., PMID:36674801
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model., PMID:36470861
Tumor Cell-Intrinsic SETD2 Deficiency Reprograms Neutrophils to Foster Immune Escape in Pancreatic Tumorigenesis., PMID:36453584
Distinct blood protein profiles associated with the risk of short-term and mid/long-term clinical relapse in patients with Crohn's disease stopping infliximab: when the remission state hides different types of residual disease activity., PMID:36008101
Surface pre-reacted glass-ionomer eluate protects gingival epithelium from penetration by lipopolysaccharides and peptidoglycans via transcription factor EB pathway., PMID:35895663
Implication of inflammation on Coxsackie virus and Adenovirus receptor expression on cardiomyocytes and the role of platelets in patients with dilated cardiomyopathy., PMID:35850451
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors., PMID:35685361
AMICA1 is a diagnostic and prognostic biomarker and induces immune cells infiltration by activating cGAS-STING signaling in lung adenocarcinoma., PMID:35248033
Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis., PMID:35064931
Coxsackievirus and Adenovirus Receptor (CXADR): Recent Findings and Its Role and Regulation in Spermatogenesis., PMID:34453733
Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of coxsackievirus and adenovirus receptor., PMID:34448537
JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy., PMID:34427588
Coxsackievirus B3 Infection of Human iPSC Lines and Derived Primary Germ-Layer Cells Regarding Receptor Expression., PMID:33513663
Whole-Exome Sequencing Identified Novel CLMP Mutations in a Family With Congenital Short Bowel Syndrome Presenting Differently in Two Probands., PMID:33384711
Role of coxsackie-adenovirus receptor in cardiac development and pathogenesis of congenital heart disease., PMID:33369284
CXADR-like membrane protein protects against heart injury by preventing excessive pyroptosis after myocardial infarction., PMID:33084169
Induction of the Coxsackievirus and Adenovirus Receptor in Macrophages During the Formation of Atherosclerotic Plaques., PMID:32852032
Membrane protein CAR promotes hematopoietic regeneration upon stress., PMID:32586901
Skin barrier damage after exposure to paraphenylenediamine., PMID:31783056
Isoform specific editing of the coxsackievirus and adenovirus receptor., PMID:31394408
The Cxadr-Adam10 complex plays pivotal roles in tight junction integrity and early trophoblast development in mice., PMID:31373105
First Report of Congenital Short Bowel Syndrome in an Iranian Patient Caused by a Mutation in the CLMP Gene., PMID:31061750
Corrigendum to: Cytoplasmic polyadenylation element binding protein 2 (CPEB2) is required for tight-junction assembly for establishment of porcine trophectoderm epithelium., PMID:31039976
Sertoli cell–specific coxsackievirus and adenovirus receptor regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation., PMID:30892947
Characterization of a novel species of adenovirus from Japanese microbat and role of CXADR as its entry factor., PMID:30679679
For research use only. Not for human or drug use.
