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Recombinant Human HBB Protein, N-His

Catalog #:   YHF62901 Specific References (49) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P68871
Protein length: Met1-His147
Overview

Catalog No.

YHF62901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-His147

Predicted molecular weight

18.31 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P68871

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Hemoglobin subunit beta, HBB, Beta-globin, Hemoglobin beta chain

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human HBB protein
References

Cigarette Smoke-Induced PPAR Signaling Dysregulation Accelerates Alzheimer's Disease Pathogenesis and Cognitive Decline in 5xFAD Mice., PMID:40513939

Screening and identification of novel protein markers of early-stage lung cancer and construction and application of screening models., PMID:40496615

PDE3B and HBB are key prognostic biomarkers driving cell proliferation and regulating immune microenvironment in breast cancer., PMID:40462176

A comprehensive, multi-center, immunogenomic analysis of melanoma brain metastases., PMID:40457397

Generation of integration-free induced pluripotent stem cell (iPSC) line MURAi002-A from hemoglobin E/β-thalassemia disease patient harboring βE/β0 (CD41/42, -CTTT) compound heterozygous mutation., PMID:40441082

Hb Lepore Rochester-MN, a novel βδβ double crossover hemoglobin variant., PMID:40413840

Splenic comparative transcriptome analysis reveals the immunological mode of undomesticated Gayal (Bos frontalis) for adapting to harsh environments., PMID:40394466

Investigate the Effect of ZFP64 on mRNA Expression of HBG Based on Bioinformatics and Experimental Validation., PMID:40392482

Genetic polymorphism of novel SNP rs5006884 in OR51B6 and SNP rs4499252 in AHSP among transfusion-dependent and non-transfusion-dependent β-thalassemia/Hb E patients in Thailand: a multivariate analysis of clinical and genetic polymorphism., PMID:40377674

Crosstalk Between Sickle Cell Disease and Ferroptosis., PMID:40332185

[Serum proteomics and machine learning unveil new diagnostic biomarkers for tuberculosis in adolescents and young adults]., PMID:40328710

Kompetitive allele specific PCR (KASP) based genotyping of sickle gene in the selected sub-ethnic tribal population of Gujarat and Madhya Pradesh., PMID:40314324

Antioxidant Activity and Chemical Alterations of Honeybee Brood Bio-Peptides Interacting with Honey Under Moist-Dried Thermal Aging., PMID:40227234

Generation of an integration-free induced pluripotent stem cell line, MURAi006-A, from a hemoglobin E/β-thalassemia patient harboring the βE/β0 (Codon 17, A > T) compound heterozygous mutation., PMID:40179812

Genome editing strategies for targeted correction of β-globin mutation in sickle cell disease: From bench to bedside., PMID:40165374

Molecular Characterization of Complex Thalassemia with Multiple Variants in β-Globin Gene Cluster and the Identification of a Novel Structural Rearrangement in γ-Globin Gene., PMID:40140352

SunTag-PE: a modular prime editing system enables versatile and efficient genome editing., PMID:40097588

Genetic architecture of the red blood cell proteome in genetically diverse mice reveals central role of hemoglobin beta cysteine redox status in maintaining circulating glutathione pools., PMID:40093052

Interrogating mediators of single-cell transcriptional changes in the acute damaged cerebral cortex: Insights into endothelial-astrocyte interactions., PMID:40090391

Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction., PMID:40060963

Newborn Screening for Sickle Cell Disease and Thalassemia., PMID:40053336

Hereditary Angioedema with Normal C1 Inhibitor: an Updated International Consensus Paper on Diagnosis, Pathophysiology, and Treatment., PMID:40053270

Decoding Allergenicity Modulation in Cold Argon Plasma-Treated Casein: A Multi-Omics Exploration., PMID:40048467

Knowledge about globin genetics for precision diagnosis of hemoglobinopathies: A case Study., PMID:40023305

A differentiated β-globin gene replacement strategy uses heterologous introns to restore physiological expression., PMID:40022449

Combined heterozygosity for hemoglobin Paksé, α-thalassemia and for hemoglobin E, β- thalassemia ̵ first appearance in Europe., PMID:40016398

Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations., PMID:40010352

Analysis of genotypic distribution and rare variants of patients with α/β-thalassemia screened in one hospital in Beijing, China., PMID:39985037

Type 2 immunity in allergic diseases., PMID:39962262

Bidirectional Mendelian Randomization identifies plasma proteins associated with urticaria risk., PMID:39961865

Metabolic and Proteomic Divergence is Present in Spleens and Livers from Berkeley Sickle Cell Anemia and β-Thalassemia Mice., PMID:39947632

Transcriptomic signatures of severe acute mountain sickness during rapid ascent to 4,300 m., PMID:39944919

Plasma proteome fingerprint in kidney diseases., PMID:39896931

A replication study of novel fetal hemoglobin-associated genetic variants in sickle cell disease-only cohorts., PMID:39886999

A next-generation sequencing-based universal target panel and algorithm for one-stop detection of copy number alterations and single-nucleotide variations in the HBB gene cluster for rapid diagnosis of β-thalassemia., PMID:39820710

Enhancing Thalassemia Diagnosis: Advantages of Third-Generation Sequencing., PMID:39808152

A Rare Hemoglobin Variant: Hemoglobin G-Siriraj, in a Moroccan Patient., PMID:39808144

Identification of a β-Globin Gene Mutation with the Genotype β-28(A > G), IVS-I-5(G > A)/βCD 71/72(+A) Using Third-Generation Sequencing., PMID:39780430

Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction., PMID:39763741

Transamniotic Delivery of Hematopoietic Stem Cells Genetically Modified to Carry a Human Hemoglobin Subunit Beta Gene (HBB) in a Healthy Rodent Model., PMID:39743433

First clinical and pedigree study of rare HBB: c.316-90 A > G variant in β-globin gene in Chinese population using third-generation sequencing., PMID:39738591

Hemoglobin-derived amyloid fibrils: Fibrillization mechanisms and potential applications., PMID:39736176

Molecular Characterization of δβ Thalassemia/Hereditary Persistence of Fetal Hemoglobin and Its Correlation With Clinical and Hematological Profile; a Single Center Study in North India., PMID:39731309

Hb Monza: A novel extensive HBB duplication with preserved α-β subunit interaction and unstable hemoglobin phenotype., PMID:39701095

Abnormal High HbA1c Caused by Hb Takasago Variant Firstly in a Chinese Pedigree., PMID:39662011

Molecular Identification and the Hematological Findings of Four Novel Variants in Globin Genes in Jiangxi Province of Southern China., PMID:39659024

Ocrelizumab in Early-Stage Relapsing-Remitting Multiple Sclerosis: The Phase IIIb ENSEMBLE 4-Year, Single-Arm, Open-Label Trial., PMID:39626127

The genotype and phenotype analysis in 3 cases with the rare genotype of HBB:c.316-146T > G., PMID:39585810

Single-stranded DNA with internal base modifications mediates highly efficient knock-in in primary cells using CRISPR-Cas9., PMID:39569586

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human HBB Protein, N-His [YHF62901]
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