Catalog No.
YHF62001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly2-Glu108
Predicted molecular weight
13.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P68106
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Immunophilin FKBP12.6, FKBP-12.6, FKBP1B, FKBP9, FKBP-1B, h-FKBP-12, 12.6 kDa FKBP, FK506-binding protein 1B, FKBP1L, Rotamase, FKBP12.6, OTK4, 12.6 kDa FK506-binding protein, Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B
Canine prostate cancer cell transcriptome reveals important dysregulation in PI3K/AKT/mTOR pathway., PMID:40328211
Integrated TWAS, GWAS, and RNAseq results identify candidate genes associated with reproductive traits in cows., PMID:39809816
Protein Alterations in Patients with Delirium after Cardiac Surgery: An Exploratory Case-Control Substudy of the VISION Cardiac Surgery Biobank., PMID:39786937
Integrated GWAS and transcriptome analysis reveals key genes associated with muscle fibre and fat traits in Gushi chicken., PMID:39364777
Comprehensive analysis of autophagy associated genes and immune infiltrates in cervical cancer., PMID:38800011
Gastric cancer prognosis: unveiling autophagy-related signatures and immune infiltrates., PMID:38617515
Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection., PMID:38417436
Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors., PMID:37035203
Construction of Autophagy-Related Gene Classifier for Early Diagnosis, Prognosis and Predicting Immune Microenvironment Features in Sepsis by Machine Learning Algorithms., PMID:36386585
Transcriptional epigenetic regulation of Fkbp1/Pax9 genes is associated with impaired sensitivity to platinum treatment in ovarian cancer., PMID:34454589
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels., PMID:34024231
Prognostic implications of an autophagy-based signature in colorectal cancer., PMID:33787596
The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells., PMID:32727592
Regulation of Immunity-Related Genes by Infectious Bronchitis Virus Challenge in Spleen of Laying Chickens., PMID:31985363
[Epigenetic Mechanisms of Peptide-Driven Regulation and Neuroprotective Protein FKBP1b]., PMID:31099784
Homologs of Human Dengue-Resistance Genes, FKBP1B and ATCAY, Confer Antiviral Resistance in Aedes aegypti Mosquitoes., PMID:30717390
Adaptation of the FK506 binding protein 1B to hibernation in bats., PMID:30056853
In utero electroporation-based translating ribosome affinity purification identifies age-dependent mRNA expression in cortical pyramidal neurons., PMID:29857015
FK506-Binding Protein 12.6/1b, a Negative Regulator of [Ca2+], Rescues Memory and Restores Genomic Regulation in the Hippocampus of Aging Rats., PMID:29255009
Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison., PMID:28942070
Specific and Novel microRNAs Are Regulated as Response to Fungal Infection in Human Dendritic Cells., PMID:28280489
Recent advancements in the molecular genetics of left ventricular noncompaction cardiomyopathy., PMID:27989498
Shikonin inhibits adipogenic differentiation via regulation of mir-34a-FKBP1B., PMID:26471303
Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus., PMID:26224869
FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation?, PMID:24291098
Common genetic variants in selected Ca²⁺ signaling genes and the risk of appropriate ICD interventions in patients with heart failure., PMID:24048583
Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic Glp-1 gene therapy., PMID:23828045
Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506., PMID:22349148
Disparities in the association of the ryanodine receptor and the FK506-binding proteins in mammalian heart., PMID:22328519
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors., PMID:22046132
Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons., PMID:21289178
Peptidyl-prolyl cis-trans isomerase xFKBP1B induces ectopic secondary axis and is involved in eye formation during Xenopus embryogenesis., PMID:21261611
A transcriptional signature associated with the onset of benign prostate hyperplasia in a canine model., PMID:20687213
Search for cardiac calcium cycling gene mutations in familial ventricular arrhythmias resembling catecholaminergic polymorphic ventricular tachycardia., PMID:19216760
Genetic screening of calcium regulation genes in familial hypertrophic cardiomyopathy., PMID:17655857
Evidence of association between FKBP1B and thyroid autoimmune disorders in a large Tunisian family., PMID:15497458
Association of EDNRA, but not WNK4 or FKBP1B, polymorphisms with essential hypertension., PMID:14616768
For research use only. Not for human or drug use.
