Catalog No.
YHF61901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro241
Predicted molecular weight
29.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P68104
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EEF1A, Elongation factor Tu, Leukocyte receptor cluster member 7, Elongation factor 1-alpha 1, EF-1-alpha-1, Eukaryotic elongation factor 1 A-1, EF-Tu, EF1A, eEF1A-1, LENG7, EEF1A1
Increased keratin 80 expression predicts poor prognosis and promotes oxaliplatin resistance in gastric cancer., PMID:40182597
Transcriptome analysis of multiple tissues and identification of tissue-specific genes in Lueyang black-bone chicken., PMID:40068570
Dynamic In Vivo Mapping of the Methylproteome Using a Chemoenzymatic Approach., PMID:39996454
Disruption of the eEF1A1/ARID3A/PKC-δ Complex by Neferine Inhibits Macrophage Glycolytic Reprogramming in Atherosclerosis., PMID:39973763
Targeting TUBB2B inhibits triple-negative breast cancer growth and brain-metastatic colonization., PMID:39962586
The proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases., PMID:39954016
Targeting eEF1A reprograms translation and uncovers broad-spectrum antivirals against cap or m6A protein synthesis routes., PMID:39920115
Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications., PMID:39919587
BE-43547A2 exerts hypoxia-selective inhibition on human pancreatic cancer cells through targeting eEF1A1 and disrupting its association with FoxO1., PMID:39837983
Deep multi-omics integration approach reveals new molecular features of uterine leiomyosarcoma., PMID:39708976
Temporal alterations of the nascent proteome in response to mitochondrial stress., PMID:39361503
Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance., PMID:39357516
CEP112 coordinates translational regulation of essential fertility genes during spermiogenesis through phase separation in humans and mice., PMID:39349455
N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1., PMID:39339978
Unmasking of molecular players: proteomic profiling of vitreous humor in pathologic myopia., PMID:39160465
Elongation factor 1A1 inhibition elicits changes in lipid droplet size, the bulk transcriptome, and cell type-associated gene expression in MASLD mouse liver., PMID:39136056
Synthesis and biological evaluation of vioprolide B and its dehydrobutyrine-glycine analogue., PMID:39015034
Agouti-Induced Anxiety-Like Behavior Is Mediated by Central Serotonergic Pathways in Zebrafish., PMID:38977301
UCHL3 promotes hepatocellular carcinoma progression by stabilizing EEF1A1 through deubiquitination., PMID:38965582
Hypoxia related genes modulate in similar fashion in skin fibroblast cells of yak (Bos grunniens) adapted to high altitude and native cows (Bos indicus) adapted to tropical climate during hypoxia stress., PMID:38814473
eEF1A1 regulates the expression and alternative splicing of genes associated with Parkinson's disease in U251 cells., PMID:38776049
FBXO32 Stimulates Protein Synthesis to Drive Pancreatic Cancer Progression and Metastasis., PMID:38775804
Cervical extracellular matrix hydrogel optimizes tumor heterogeneity of cervical squamous cell carcinoma organoids., PMID:38748808
CRISPR Screen Identifies the RNA-Binding Protein Eef1a1 as a Key Regulator of Myogenesis., PMID:38732031
Characterization of virus‒host recombinant variants of the hepatitis E virus., PMID:38712945
The eEF1A protein in cancer: Clinical significance, oncogenic mechanisms, and targeted therapeutic strategies., PMID:38677532
Methylated lncRNAs suppress apoptosis of gastric cancer stem cells via the lncRNA-miRNA/protein axis., PMID:38600465
MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer., PMID:38593213
N-Cinnamoylpyrrole-derived alkaloids from the genus Piper as promising agents for ischemic stroke by targeting eEF1A1., PMID:38513376
Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins., PMID:38510136
Deciphering the antidepressant effects of Rosa damascena essential oil mediated through the serotonergic synapse signaling pathway., PMID:38492791
A case of a lipoblastoma with EEF1A1::PLAG1 fusion and metaplastic ossification., PMID:38470300
Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis., PMID:38360885
Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells., PMID:38272231
Role of melanocortin system in the locomotor activity rhythms and melatonin secretion as revealed by agouti-signalling protein (asip1) overexpression in zebrafish., PMID:38241679
Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach., PMID:38220433
Methylation of elongation factor 1A by yeast Efm4 or human eEF1A-KMT2 involves a beta-hairpin recognition motif and crosstalks with phosphorylation., PMID:38199565
Integrated Bioinformatic Analysis of Differentially Expressed Genes Associated with Wound Healing., PMID:38192258
[Role of Eukaryotic Translation Elongation Factor 1 Family Members in the Tumorigenesis and Progression of Lung Adenocarcinoma]., PMID:38173097
Oncogenic activation of EEF1A2 expression: a journey from a putative to an established oncogene., PMID:38172654
Selection of reference genes in liproxstatin-1-treated K562 Leukemia cells via RT-qPCR and RNA sequencing., PMID:38165476
Mapping of the gene network that regulates glycan clock of ageing., PMID:38149987
Ocular surface changes in mice with streptozotocin-induced diabetes and diabetic polyneuropathy., PMID:38141818
Efficient selection of knocked-in pluripotent stem cells using a dual cassette cellular elimination system., PMID:38086384
USP11 potentiates HGF/AKT signaling and drives metastasis in hepatocellular carcinoma., PMID:37973952
Synaptic Involvement of the Human Amygdala in Parkinson's Disease., PMID:37947401
Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins., PMID:37901457
Insensitive Effects of Inflammatory Cytokines on the Reference Genes of Synovial Fluid Resident-Mesenchymal Stem Cells Derived from Rheumatoid Arthritis Patients., PMID:37894839
YTHDF2 facilitates aggresome formation via UPF1 in an m6A-independent manner., PMID:37803021
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate., PMID:37797623
For research use only. Not for human or drug use.
