Catalog No.
YHF57001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly2-Val170
Predicted molecular weight
46.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P63098
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CNB, Calcineurin subunit B type 1, CNA2, Protein phosphatase 3 regulatory subunit B alpha isoform 1, Protein phosphatase 2B regulatory subunit 1, PPP3R1
Chronic Exercise Protects Against Cognitive Deficits in an Alzheimer's Disease Model by Enhancing Autophagy and Reducing Mitochondrial Abnormalities., PMID:40448811
Exploring potential drug targets for SLE through Mendelian randomization and network pharmacology., PMID:39823480
Postsynaptic competition between calcineurin and PKA regulates mammalian sleep-wake cycles., PMID:39506111
SMURF1 mediates damaged lysosomal homeostasis by ubiquitinating PPP3CB to promote the activation of TFEB., PMID:39324484
Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis., PMID:39263947
Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts., PMID:38812487
Protein phosphatases regulate the formation of Müller glia-derived progenitor cells in the chick retina., PMID:38679247
Protein phosphatases regulate the formation of Müller glia-derived progenitor cells in the chick retina., PMID:38168320
Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls., PMID:38158702
Generation of four induced pluripotent stem cells lines from PBMC of the DFNA58 family members: Two hearing-impaired duplication carriers (USPi006-A e USPi007-A) and two normal-hearing noncarriers (USPi004-A and USPi005-A)., PMID:37595341
LncRNA HOXD-AS2 regulates miR-3681-5p/DCP1A axis to promote the progression of non-small cell lung cancer., PMID:37065560
PPP3R1 Promotes MSCs Senescence by Inducing Plasma Membrane Depolarization and Increasing Ca2+ Influx., PMID:36901851
Narirutin activates TFEB (transcription factor EB) to protect against Acetaminophen-induced liver injury by targeting PPP3/calcineurin., PMID:36779633
Identification of immune microenvironment subtypes and signature genes for Alzheimer's disease diagnosis and risk prediction based on explainable machine learning., PMID:36569892
New Insights into the Identity of the DFNA58 Gene., PMID:36553541
Decorin-induced, preeclampsia-associated microRNA-512-3p restrains extravillous trophoblast functions by targeting USF2/PPP3R1 axis., PMID:36299488
Dynamic miRNA profile of host T cells during early hepatic stages of Schistosoma japonicum infection., PMID:36119054
Mechanisms underlying microRNA-222-3p modulation of methamphetamine-induced conditioned place preference in the nucleus accumbens in mice., PMID:35881147
Breast Meat Fatty Acid Profiling and Proteomic Analysis of Beijing-You Chicken During the Laying Period., PMID:35782537
Integrative genomic analysis of PPP3R1 in Alzheimer's disease: a potential biomarker for predictive, preventive, and personalized medical approach., PMID:34956428
Uncovering potential novel biomarkers and immune infiltration characteristics in persistent atrial fibrillation using integrated bioinformatics analysis., PMID:34198460
TMT-based quantitative proteomics analysis reveals the key proteins related with the differentiation process of goat intramuscular adipocytes., PMID:34090334
Immune-related gene expression signatures in colorectal cancer., PMID:34079596
Thyroarytenoid Muscle Gene Expression in a Rat Model of Early-Onset Parkinson's Disease., PMID:34057223
Quantitative proteomics analysis reveals unique but overlapping protein signatures in HIV infections., PMID:34030014
Effects of PIM3 in prognosis of colon cancer., PMID:33928496
Dysfunction of the Klotho-miR-30s/TRPC6 axis confers podocyte injury., PMID:33862465
The CnB1 p.D102A variant is linked to dilated cardiomyopathy via impaired Calcineurin activity., PMID:32882262
The Protective Effects of Calcineurin on Pancreatitis in Mice Depend on the Cellular Source., PMID:32445858
A rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58., PMID:32337552
Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response., PMID:31754133
Validation of a priori candidate Alzheimer's disease SNPs with brain amyloid-beta deposition., PMID:31745181
Transcriptome profiling of muscle in Nelore cattle phenotypically divergent for the ribeye muscle area., PMID:31351181
Varicose veins of lower extremities: Insights from the first large-scale genetic study., PMID:30998689
Intrinsic-overlapping co-expression module detection with application to Alzheimer's Disease., PMID:30466046
The calcineurin regulatory subunit polymorphism and the treatment efficacy of tacrolimus for idiopathic membranous nephropathy., PMID:30388516
Modulation of intracellular calcium signaling by microRNA-34a-5p., PMID:30262862
MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium., PMID:29973623
Effects of let-7e on LPS-Stimulated THP-1 Cells Assessed by iTRAQ Proteomic Analysis., PMID:29505169
Mining the nucleus accumbens proteome for novel targets of alcohol self-administration in male C57BL/6J mice., PMID:29502276
Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice., PMID:29422055
MiR-548a-3p Promotes Keratinocyte Proliferation Targeting PPP3R1 after Being Induced by IL-22., PMID:29181737
A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons., PMID:29158107
Association of CnB 5I/5D promoter gene polymorphism and serum calcineurin levels in early onset of coronary artery disease of south Indian cohort., PMID:28827117
Calcineurin inhibitors regulate fibroblast growth factor 23 (FGF23) synthesis., PMID:28761977
Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members., PMID:28540409
On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome., PMID:28247455
NFATC1 genotypes affect acute rejection and long-term graft function in cyclosporine-treated renal transplant recipients., PMID:28244807
Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy., PMID:27907007
MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes., PMID:26436650
For research use only. Not for human or drug use.
