Catalog No.
YHF56501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu192
Predicted molecular weight
23.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P63000
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related C3 botulinum toxin substrate 1, Ras-like protein TC25, TC25, p21-Rac1, Cell migration-inducing gene 5 protein, RAC1
Mechanical control of breast cancer malignancy by promotion of mevalonate pathway enzyme synthesis., PMID:40516663
Rapid memory shift between different synaptic ensembles promotes forgetting in Drosophila., PMID:40513570
Regulation of epithelial-mesenchymal plasticity in pancreatic ductal adenocarcinoma: Role of key molecules in tumor differentiation and therapy., PMID:40499272
Negative feedback equalizes polarity sites in a multi-budding yeast., PMID:40482649
CD44-downregulation in multiple myeloma inhibits cytoskeleton rearrangement through actin depolymerization., PMID:40481899
GAS6/AXL signaling promotes M2 microglia efferocytosis to alleviate neuroinflammation in sepsis-associated encephalopathy., PMID:40480981
RAC1 Regulates Shh-Medulloblastoma Growth via GLI-Mediated Transcription., PMID:40475618
Cryo-ET of actin cytoskeleton and membrane structure in lamellipodia formation using optogenetics., PMID:40475257
Missense ABI2 variants linked to a neurodevelopmental disorder with intellectual disability, epilepsy, hypoplasia of the corpus callosum, and white matter abnormalities., PMID:40475134
Computation model predicts Rho GTPase function with the Plexin Transmembrane receptor GAP activity on Rap1b via dynamic allosteric changes., PMID:40462934
ELMO2 is an essential regulator of carotid artery development., PMID:40456777
Renal Dysfunction Induced by Sodium p-Perfluorous Nonenoxybenzenesulfonate in Mice: Insights from the Intrinsic Mechanisms of Proteinuria., PMID:40444664
Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway., PMID:40441470
Sodium/hydrogen exchanger 8 affects sheet migration of human intestinal epithelial cells (HT29MTX) by influencing the actin cytoskeletal rearrangement., PMID:40434024
YAP controls cell migration and invasion through a Rho GTPase switch., PMID:40424361
MicroRNA-129-5p-mediated translational repression of microglial ROCK1 leads to enhanced phagocytosis., PMID:40419128
[RGL1 overexpression promotes metastasis of colorectal cancer by upregulating motile focal adhesion assembly via activating the CDC42/RAC1 complex]., PMID:40415435
RHOA-associated disorder can be non-mosaic., PMID:40414526
Thymic egress and peripheral T cell homeostasis regulated by Rho GTPase-activating protein 30., PMID:40404920
Phospholipase C epsilon 1 aggravates β-amyloid-associated cognitive impairments and pyroptosis through activating the RAC1-STAT3 pathway in Alzheimer disease models., PMID:40402834
SECS, drugs, and Rac1&Rho: regulation of EnNaC in vascular endothelial cells., PMID:40402207
Focal Adhesion Kinase Orchestrates GLUT4 Translocation and Glucose Uptake via Cytoskeletal Turnover in Primary Adipocytes., PMID:40396386
The role of RAC1 in resistance to targeted therapies in cancer., PMID:40396280
LncRNA NEAT1 regulation of the miR-101-3p/RAC1 axis affects cervical cancer aerobic glycolysis and progression., PMID:40394096
Morphological control of merlin-Rac antagonism in proliferation-promoting signaling., PMID:40392939
TIAM1 drives prostatic branching phenotype and is a potential therapeutic target for benign prostatic hyperplasia., PMID:40392613
Equol neutralizes toxin B to combat Clostridioides difficile infection without disrupting the gut microbiota., PMID:40378594
Pharmacological inhibition of hypoxia induced acidosis employing a CAIX inhibitor sensitizes gemcitabine resistant PDAC cells., PMID:40369181
AHCYL1 mediates the tumor-promoting effect of PREX2 in non-small cell lung carcinoma., PMID:40365293
Roles played by IL-8 in altering dynamics of trabecular meshwork cells after human cytomegalovirus infection., PMID:40353220
A Novel Therapeutic Strategy for Ameliorating Hyperglycemia-Induced Liver Injury via Overexpression of the Carboxyl Terminus of HSP70-Interacting Protein in Wharton's Jelly Mesenchymal Stem Cells., PMID:40350690
Mechanistic insights into CLNS1A-mediated chemoresistance and tumor progression in non-small cell lung cancer., PMID:40345428
Myeloid-specific deficiency of group VIA calcium-independent phospholipase A2 preconditions myeloid cells for injury resolution after acetaminophen exposure., PMID:40344700
Silencing of Rac1 and Arf6 reduces time-dependent and carbachol-induced contractions, proliferation, survival and growth in human bladder smooth muscle cells., PMID:40332567
Redox and actin, a fascinating story., PMID:40328105
The Rho GEF Trio functions in contact inhibition of locomotion of neural crest cells by interacting with Ptk7., PMID:40326503
Identification of a disulfidptosis-related genes signature for diagnostic and immune infiltration characteristics in cervical cancer., PMID:40305445
Benzene metabolites increase vascular permeability by activating heat shock proteins and Rho GTPases., PMID:40300100
Development of Acquired Resistance in Alpelisib-treated Gastric Cancer Cells With PIK3CA Mutations and Overcoming Strategies., PMID:40295072
MAP17 as a Mediator of HGF-induced Proliferation and Invasion in Gastric Cancer., PMID:40295039
Oligodendrocyte myelin glycoprotein impairs dendritic arbors via schizophrenia risk gene Trio., PMID:40274132
Treponema pallidum Protein TpF1 Inhibits Migration by Impairing Actin Polymerization via Toll-Like Receptor 4/PI3K/AKT in Microglia., PMID:40272988
Fluorometholone inhibits corneal epithelial proliferation, migration via targeting Rho GTPases: RhoA, Rac1, and Cdc42., PMID:40268157
Fucoxanthin Targets β1 Integrin to Disrupt Adhesion and Migration in Human Glioma Cells., PMID:40261208
Activation of a Potassium Channel Mutation That Causes Spinocerebellar Ataxia Promotes Aggregation of the RhoGEF Domain-Containing Protein Plekhg4., PMID:40249242
Emerging oral Treponema membrane proteins disorder neutrophil phosphoinositide signaling via phosphatidylinositol-4-phosphate 5-kinase., PMID:40248422
Chloride intracellular channel (CLIC) protein function in S1P-induced Rac1 activation requires membrane localization of the C-terminus, but not thiol-transferase nor ion channel activities., PMID:40235733
Pathogenesis of Focal Segmental Glomerulosclerosis Caused by a Leu754Val Mutation in ARHGAP32., PMID:40231370
Colorectal cancer stem cells develop NK cell resistance via homotypic cell-in-cell structures suppressed by Stathmin1., PMID:40225568
Phillyrin counters β2 integrin-mediated neutrophil adhesion and chemotaxis to alleviate endotoxin-induced acute lung injury in neonatal rats., PMID:40210127
For research use only. Not for human or drug use.
