Catalog No.
YHF47501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly127
Predicted molecular weight
16.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61970
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PP15, NUTF2, NTF-2, Nuclear transport factor 2, Placental protein 15, NTF2
Host and bacterial urine proteomics might predict treatment outcomes for immunotherapy in advanced non-small cell lung cancer patients., PMID:40297587
Native top-down proteomics enables discovery in endocrine-resistant breast cancer., PMID:40186031
Native top-down proteomics reveals EGFR-ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth., PMID:37546719
A review on the role of LINC00173 in human cancers., PMID:36774758
NUTF2 as a Prognostic Indicator and Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma., PMID:36577127
Gene Networks of Hyperglycemia, Diabetic Complications, and Human Proteins Targeted by SARS-CoV-2: What Is the Molecular Basis for Comorbidity?, PMID:35806251
Identification of NUTF2 as a Candidate Diagnostic and Prognostic Biomarker Associated with Immune Infiltration in Head and Neck Squamous Cell Carcinoma., PMID:35221694
Nuclear Transporting Factor 2 as a Novel Biomarker of Head and Neck Squamous Cell Carcinoma and Associated with T/B Cell Receptor Signaling Pathway., PMID:35155672
A Pan-Cancer Analysis of the Oncogenic Role of Nuclear Transport Factor 2 in Human Cancers., PMID:35155261
Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies., PMID:35098921
Nuclear Transport Factor 2 (NTF2) suppresses WM983B metastatic melanoma by modifying cell migration, metastasis, and gene expression., PMID:34880267
Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time., PMID:34707094
DNA-Origami NanoTrap for Studying the Selective Barriers Formed by Phenylalanine-Glycine-Rich Nucleoporins., PMID:34324340
Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations., PMID:31442033
Characterization of the nuclear import pathway for BLM protein., PMID:29017749
Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding., PMID:26823604
Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?, PMID:26339717
'Conceptualizing' the Endometrium: Identification of Conceptus-Derived Proteins During Early Pregnancy in Cattle., PMID:25947061
Promiscuous binding of Karyopherinβ1 modulates FG nucleoporin barrier function and expedites NTF2 transport kinetics., PMID:25692596
NPC mimics: probing the mechanism of nucleocytoplasmic transport., PMID:24857739
Crystal structures of the human G3BP1 NTF2-like domain visualize FxFG Nup repeat specificity., PMID:24324649
Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation., PMID:22880006
Chromophore maturation and fluorescence fluctuation spectroscopy of fluorescent proteins in a cell-free expression system., PMID:22093611
Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells., PMID:21195711
Brightness analysis by Z-scan fluorescence fluctuation spectroscopy for the study of protein interactions within living cells., PMID:20682277
Overexpression of nuclear transport factor 2 may protect against diabetic retinopathy., PMID:19404486
A new role for nuclear transport factor 2 and Ran: nuclear import of CapG., PMID:18266911
A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes., PMID:17693259
Association of nuclear pore FG-repeat domains to NTF2 import and export complexes., PMID:17161424
Significant proportions of nuclear transport proteins with reduced intracellular mobilities resolved by fluorescence correlation spectroscopy., PMID:17056062
Nuclear pore complex proteins in Alzheimer disease., PMID:16410748
Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS., PMID:15838894
Nuclear transport of single molecules: dwell times at the nuclear pore complex., PMID:15657394
An ATP-dependent activity that releases RanGDP from NTF2., PMID:15155737
Solution NMR study of the interaction between NTF2 and nucleoporin FxFG repeats., PMID:14556747
Optical microwell assay of membrane transport kinetics., PMID:14507695
Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15., PMID:12835756
Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid., PMID:12364547
The molecular mechanism of translocation through the nuclear pore complex is highly conserved., PMID:12082159
Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats., PMID:12065398
Functional analysis of the hydrophobic patch on nuclear transport factor 2 involved in interactions with the nuclear pore in vivo., PMID:11489893
Nuclear Ras: unexpected subcellular distribution of oncogenic forms., PMID:11455565
Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner., PMID:11294908
Dissecting the interactions between NTF2, RanGDP, and the nucleoporin XFXFG repeats., PMID:10681579
The path of RNA through nuclear pores: apparent entry from the sides into specialized pores., PMID:10633080
Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export., PMID:10567585
Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP., PMID:10543952
Plant importin alpha binds nuclear localization sequences with high affinity and can mediate nuclear import independent of importin beta., PMID:10428841
Efficiency of importin alpha/beta-mediated nuclear localization sequence recognition and nuclear import. Differential role of NTF2., PMID:10336485
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human., PMID:10228171
For research use only. Not for human or drug use.
