Catalog No.
YHF41301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile389-Asn556
Predicted molecular weight
20.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61221
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HuHP68, RNS4I, RNASEL1, RNase L inhibitor, 2'-5'-oligoadenylate-binding protein, RLI, ABCE1, ATP-binding cassette sub-family E member 1, RNASELI, Ribonuclease 4 inhibitor
A novel lncRNA ABCE1-5 regulates pulmonary fibrosis by targeting KRT14., PMID:40111939
The association of ABC proteins with multidrug resistance in cancer., PMID:39571941
Translation stalling induced mitochondrial entrapment of ribosomal quality control related proteins offers cancer cell vulnerability., PMID:39315278
The ellagitannin metabolite urolithin C attenuated cognitive impairment by inhibiting neuroinflammation via downregulation of MAPK/NF-kB signaling pathways in aging mice., PMID:39303538
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome., PMID:39238930
Phylogenetic insight into ABCE gene subfamily in plants., PMID:38911295
CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy., PMID:38809982
Identification of biomimetic nanoplatform-mediated delivery of si-ISG15 for treatment of triple-negative breast cancer., PMID:38401776
Restoration of miR-299-3p promotes macrophage phagocytosis and suppresses malignant phenotypes in breast cancer carcinogenesis via dual-targeting CD47 and ABCE1., PMID:38394889
ABCE1 selectively promotes HIF-1α transactivation of angiogenic gene expression., PMID:37738929
[Tanshinone IIA inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis and autophagy by regulating ABCE1]., PMID:37366130
Casein Kinase 2α Augments Oxaliplatin Resistance in Colorectal Cancer Cells by Increasing ABCE1 Expression., PMID:37247928
Identification of RALA as a Therapeutic Target and Prognostic Predictor of Osteosarcoma., PMID:36817861
Relocalization of Translation Termination and Ribosome Recycling Factors to Stress Granules Coincides with Elevated Stop-Codon Readthrough and Reinitiation Rates upon Oxidative Stress., PMID:36672194
A pan-cancer analysis of the oncogenic role of ATP binding cassette subfamily E member 1 (ABCE1) in human tumors: An observational study., PMID:36401432
Autoimmune gene expression profiling of fingerstick whole blood in Chronic Fatigue Syndrome., PMID:36284352
Prevention of ribosome collision-induced neuromuscular degeneration by SARS CoV-2-encoded Nsp1., PMID:36170200
Genome-Wide Identification, Characterisation and Phylogenetic Analysis of 52 Striped Catfish (Pangasianodon hypophthalmus) ATP-Binding Cassette (ABC) Transporter Genes., PMID:35966264
Human ABCE1 exhibits temperature-dependent heterologous co-functionality in S. cerevisiae., PMID:35792803
The Expression and Effect of ABCE1 in Gastric Adenocarcinoma., PMID:35737213
[Role of Proteins Interacting with the eRF1 and eRF3 Release Factors in the Regulation of Translation and Prionization]., PMID:35403616
Rebirth of the translational machinery: The importance of recycling ribosomes., PMID:35147231
Nsp1 of SARS-CoV-2 stimulates host translation termination., PMID:34793288
Embryonic LTR retrotransposons supply promoter modules to somatic tissues., PMID:34675070
Translation of ABCE1 Is Tightly Regulated by Upstream Open Reading Frames in Human Colorectal Cells., PMID:34440115
Genetic depletion of the RNA helicase DDX3 leads to impaired elongation of translating ribosomes triggering co-translational quality control of newly synthesized polypeptides., PMID:34358325
Iron in Translation: From the Beginning to the End., PMID:34068342
40S ribosome profiling reveals distinct roles for Tma20/Tma22 (MCT-1/DENR) and Tma64 (eIF2D) in 40S subunit recycling., PMID:34016977
Identification of novel prognostic biomarkers by integrating multi-omics data in gastric cancer., PMID:33902514
Addressing Antiretroviral Drug Resistance with Host-Targeting Drugs-First Steps towards Developing a Host-Targeting HIV-1 Assembly Inhibitor., PMID:33802145
ABCE1 Regulates RNase L-Induced Autophagy during Viral Infections., PMID:33670646
LncRNA HOTAIRM1 knockdown inhibits cell glycolysis metabolism and tumor progression by miR-498/ABCE1 axis in non-small cell lung cancer., PMID:33537917
A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes., PMID:33289941
Identification of an Antiretroviral Small Molecule That Appears To Be a Host-Targeting Inhibitor of HIV-1 Assembly., PMID:33148797
Mass spectrometry-based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin., PMID:33128234
A Path toward SARS-CoV-2 Attenuation: Metabolic Pressure on CTP Synthesis Rules the Virus Evolution., PMID:33125064
Mutational analysis of Arabidopsis thaliana ABCE2 identifies important motifs for its RNA silencing suppressor function., PMID:33040451
Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence., PMID:33023155
MicroRNA‑145 promotes the apoptosis of leukemic stem cells and enhances drug‑resistant K562/ADM cell sensitivity to adriamycin via the regulation of ABCE1., PMID:32945355
Readthrough of stop codons under limiting ABCE1 concentration involves frameshifting and inhibits nonsense-mediated mRNA decay., PMID:32941650
FOXO3a-dependent Parkin regulates the development of gastric cancer by targeting ATP-binding cassette transporter E1., PMID:32914432
Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3' UTR-Directed Regulation and Nonsense-Mediated Decay., PMID:32668236
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression., PMID:32651259
Multiple ATP-binding cassette transporters genes are involved in thiamethoxam resistance in Aphis gossypii glover., PMID:32527432
Structural Insights into the Mammalian Late-Stage Initiation Complexes., PMID:32268096
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex., PMID:32064661
ABCE1 Acts as a Positive Regulator of Exogenous RNA Decay., PMID:32033097
Extraction of mRNA from Stalled Ribosomes by the Ski Complex., PMID:32006463
Identification of key genes for predicting colorectal cancer prognosis by integrated bioinformatics analysis., PMID:31897151
Long noncoding RNA FAM201A mediates the metastasis of lung squamous cell cancer via regulating ABCE1 expression., PMID:31841188
For research use only. Not for human or drug use.
