Catalog No.
YHF12501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met253-Ser472
Predicted molecular weight
24.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55317
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HNF-3-alpha, Transcription factor 3A, TCF3A, HNF3A, HNF-3A, FOXA1, TCF-3A, Hepatocyte nuclear factor 3-alpha, Forkhead box protein A1
Astragaloside IV inhibits the growth of obesity-associated triple-negative breast cancer by activating FOXA1 transcription factor to regulate GAL3ST1-GalCer signaling and remodel sphingolipid metabolism., PMID:40472617
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression., PMID:40445264
Effective therapeutic targeting of tumor lineage plasticity in neuroendocrine prostate cancer by BRD4 inhibitors., PMID:40370549
Robust Consensus Molecular Subtyping of Muscle-Invasive Bladder Cancer Via 3' RNA Sequencing of Formalin-Fixed Paraffin-Embedded Tissues: Potential Impact for Clinical and Trial Settings., PMID:40320243
SAE1 May Play a Pro-Carcinogenic Role in Pancreatic Adenocarcinoma: A Comprehensive Study Integrating Multiple Pieces of Evidence., PMID:40302186
The Influence of the Germline HSD3B1 Adrenal-Permissive Allele (c.1100 C) on the Somatic Alteration Landscape, the Transcriptome, and Immune Cell Infiltration in Prostate Cancer., PMID:40282446
Downregulation of NNMT affects trophoblast function via inhibiting COMP/CD36/ERK1/2 axis in recurrent spontaneous abortion., PMID:40274084
Surrogate molecular classification of LAR breast cancer in routine workflow., PMID:40265610
FOXA1 Targets NEK2 to Mediate Cisplatin Resistance in Lung Adenocarcinoma Cells by Activating DNA Damage Repair., PMID:40233258
The role of FOXA1 and miR-212-3p in molecular modulation of doxorubicin resistance in liver cancer., PMID:40216647
Genomic features of liquid biopsies from patients with prostate cancer with and without ductal adenocarcinoma., PMID:40172755
The Diagnostic Role of TFF1, TFF3, FOXA1, CA XII and TRPS1 in Serous Effusions., PMID:40170411
Genetic susceptibility to lung squamous cell carcinoma: new insights on 9q33.2 variants and tobacco smoking., PMID:40168134
FOXA1-mediated transcription of MFAP2 facilitates cell growth, metastasis and cisplatin resistance in uterine corpus endometrial carcinoma., PMID:40153018
Manganese-induced Precocious Puberty Alters Mammary Epithelial Cell Proliferation in Female Rats., PMID:40105700
HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia-Reperfusion Injury., PMID:40091743
Circular RNA Circ_0002762 promotes cell migration and invasion in cervical squamous cell carcinoma via activating RelA/nuclear factor kappa B (Nf-kB) signalling pathway., PMID:40083243
Histone demethylase LSD1 promotes castration-resistant prostate cancer by causing widespread gene expression derangements., PMID:40033561
[Characteristic PIK3CA gene mutation in breast cancer]., PMID:40032415
CircDIAPH1 Promotes Liver Metastasis and Development of Colorectal Cancer by Initiation of CEACAM6 Expression., PMID:39987565
Interferon-γ/Janus Kinase 1/STAT1 Signaling Represses Forkhead Box A1 and Drives a Basal Transcriptional State in Muscle-Invasive Bladder Cancer., PMID:39986350
CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer., PMID:39954255
Prospective observational study on the relationships between genetic alterations and survival in Japanese patients with metastatic castration-sensitive prostate cancer: the impact of IDC-P., PMID:39937427
POLM inhibits porcine epidemic diarrhea virus replication by degrading multiple viral structural proteins., PMID:39927776
FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss., PMID:39920313
Homologous recombination repair status in metastatic prostate cancer by next-generation sequencing and functional immunofluorescence., PMID:39914385
SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer., PMID:39858458
Relationship between androgen receptor and androgen receptor-related protein expression in breast cancers focusing on morphologically identified carcinoma with apocrine differentiation., PMID:39843553
The expression of transcription factors in the human fetal subthalamic nucleus suggests its origin from the first hypothalamic prosomere., PMID:39831906
Spatial Genomics Identifies Heat Shock Proteins as Key Molecular Changes Associated to Adipose Periprostatic Space Invasion in Prostate Cancer., PMID:39796635
FOXA1 activates NOLC1 transcription through NOTCH pathway to promote cell stemness in lung adenocarcinoma., PMID:39789998
Silencing FOXA1 suppresses inflammation caused by LPS and promotes osteogenic differentiation of periodontal ligament stem cells through the TLR4/MyD88/NF-κB pathway., PMID:39760528
Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes., PMID:39745364
Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer., PMID:39709604
Foxa1 disruption enhances human cell integration in human-mouse interspecies chimeras., PMID:39708115
The Lyn/RUVBL1 Complex Promotes Colorectal Cancer Liver Metastasis by Regulating Arachidonic Acid Metabolism Through Chromatin Remodeling., PMID:39665272
Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer., PMID:39633177
Pseudogene KRT17P3 Promotes NSCLC Progression Through Mir-338-3p/USP7/C-Myc., PMID:39626929
FOXA1 knockdown alleviates inflammation and enhances osteogenic differentiation of periodontal ligament stem cells via STAT3 pathway., PMID:39623394
Reversal of endocrine resistance via N6AMT1-NEDD4L pathway-mediated p110α degradation., PMID:39623076
S1PR1 suppresses lung adenocarcinoma progression through p-STAT1/miR-30c-5 p/FOXA1 pathway., PMID:39551792
FOXA1 enhances antitumor immunity via repressing interferon-induced PD-L1 expression in nasopharyngeal carcinoma., PMID:39542656
Multi-modal analysis of human hepatic stellate cells identifies novel therapeutic targets for metabolic dysfunction-associated steatotic liver disease., PMID:39522884
FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma., PMID:39515329
A small molecule that reshapes the chromatin dynamics of FOXA1., PMID:39515290
The Tmem16a chloride channel is required for mucin maturation after secretion from goblet-like cells in the Xenopus tropicalis tadpole skin., PMID:39461969
Loss of miR-634 contributes to the formation FOXA1-positive triple negative breast cancer subtype., PMID:39441384
In Silico Analysis Uncovers FOXA1 as a Potential Biomarker for Predicting Neoadjuvant Chemotherapy Response in Fine-Needle Aspiration Biopsies., PMID:39440050
Chromatin interaction maps identify oncogenic targets of enhancer duplications in cancer., PMID:39424324
A regulatory variant rs9379874 in T1D risk region 6p22.2 affects BTN3A1 expression regulating T cell function., PMID:39417845
For research use only. Not for human or drug use.
