Catalog No.
YHF09801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg236-Ser352
Predicted molecular weight
15.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55103
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
INHBC, Inhibin beta C chain, Activin beta-C chain
Therapeutic Targets for Sepsis: Multicenter Proteome-Wide Analyses and Experimental Validation., PMID:40459852
Plasma Proteomic Signatures of Physical Activity Provide Insights into Biological Impacts of Physical Activity and its Protective Role Against Dementia., PMID:39867359
Circulating proteomic profiles are associated with type 2 diabetes in Asian populations - a longitudinal study., PMID:39842943
TGF-β superfamily-induced transcriptional activation pathways establish the RAD52-dependent ALT machinery during malignant transformation of MPNSTs., PMID:39488637
Bidirectional Mendelian Randomization Highlights Causal Relationships Between Circulating INHBC and Multiple Cardiometabolic Diseases and Traits., PMID:39283655
Identification of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with transcriptome., PMID:38898508
Plasma proteome analysis implicates novel proteins as potential therapeutic targets for chronic kidney disease: A proteome-wide association study., PMID:38828357
Comparative genomic studies on the TGF-β superfamily in blue whale., PMID:38467865
Plasma proteomic profile of abdominal obesity in older adults., PMID:38439214
A phenome-wide approach to identify causal risk factors for deep vein thrombosis., PMID:37951941
A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation., PMID:37774922
Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage., PMID:37365616
Activin B and Activin C Have Opposing Effects on Prostate Cancer Progression and Cell Growth., PMID:36612143
Molecular Characterization of TGF-Beta Gene Family in Buffalo to Identify Gene Duplication and Functional Mutations., PMID:35893038
The potential mechanism of INHBC and CSF1R in diabetic nephropathy., PMID:32141565
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control., PMID:31985003
Key Genes and Signaling Pathways Contribute to the Pathogensis of Diabetic Nephropathy., PMID:30988245
Transcriptome Analysis of Circulating PBMCs to Understand Mechanism of High Altitude Adaptation in Native Cattle of Ladakh Region., PMID:29769561
Regional localization of activin-βA, activin-βC, follistatin, proliferation, and apoptosis in adult and developing mouse prostate ducts., PMID:28363632
Over-Expression of Activin-βC Is Associated with Murine and Human Prostate Disease., PMID:28116672
Activin-βC modulates gonadal, but not adrenal tumorigenesis in the inhibin deficient mice., PMID:25869398
Twenty-eight loci that influence serum urate levels: analysis of association with gout., PMID:25187157
The inhibin/activin signalling pathway in human gonadal and adrenal cancers., PMID:25180271
Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells., PMID:25062451
Genome-wide association study for inhibin, luteinizing hormone, insulin-like growth factor 1, testicular size and semen traits in bovine species., PMID:23785023
The inhibin-βC subunit is down-regulated, while inhibin-βE is up-regulated by interferon-β1a in Ishikawa carcinoma cell line., PMID:23580013
SNPs in the TGF-β signaling pathway are associated with increased risk of brain metastasis in patients with non-small-cell lung cancer., PMID:23284751
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function., PMID:22962313
Activin C expressed in nociceptive afferent neurons is required for suppressing inflammatory pain., PMID:22275428
Immunolabelling of the inhibin/activin-βC subunit in normal and malignant human uterine cervical tissue and cervical cancer cell lines., PMID:21109970
Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue., PMID:21092084
Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene., PMID:21063444
Inhibin/activin-betaC subunit in human endometrial adenocarcinomas and HEC-1a adenocarcinoma cell line., PMID:20952735
Inhibin/activin-betaC subunit does not represent a prognostic parameter in human endometrial cancer., PMID:20683603
Inhibin/activin-betaC and -betaE subunits in the Ishikawa human endometrial adenocarcinoma cell line., PMID:20012305
Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo., PMID:19095948
Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review)., PMID:18698484
Genetic variation in the inhibin pathway and risk of testicular germ cell tumors., PMID:18413775
Manipulation of thyroid status and/or GH injection alters hepatic gene expression in the juvenile chicken., PMID:17675858
Analysis of the function of activin betaC subunit using recombinant protein., PMID:16627954
Adenovirus-mediated overexpression of activin beta(C) subunit accelerates liver regeneration in partially hepatectomized rats., PMID:16171890
Adenovirus-mediated overexpression of the activin betaC subunit accelerates liver regeneration in partially hepatectomized rats., PMID:16085335
Should activin betaC be more than a fading snapshot in the activin/TGFbeta family album?, PMID:15925536
Cell-specific expression of betaC-activin in the rat reproductive tract, adrenal and liver., PMID:15249126
Assessment of the function of the betaC-subunit of activin in cultured hepatocytes., PMID:15039147
Activin betaC-subunit heterodimers provide a new mechanism of regulating activin levels in the prostate., PMID:12960042
Overexpression of activin beta(C) or activin beta(E) in the mouse liver inhibits regenerative deoxyribonucleic acid synthesis of hepatic cells., PMID:12865331
Changes in activin and activin receptor subunit expression in rat liver during the development of CCl4-induced cirrhosis., PMID:12706302
Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta C (Inhbc) gene., PMID:8838799
For research use only. Not for human or drug use.
