Catalog No.
YHF09301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val22-Ala255
Predicted molecular weight
28.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55083
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MFAP4, Microfibril-associated glycoprotein 4
MFAP4 Deficiency Attenuates Liver Fibrosis by Regulating Hepatic Stellate Cell Fate through Inhibition of the FAK/PI3K/NFκB Signaling Pathway., PMID:40449846
Identification of biomarkers and immune microenvironment associated with heart failure through bioinformatics and machine learning., PMID:40406620
Chronic gingivitis increases the risk of early-onset Alzheimer's disease., PMID:40320792
Pathological Changes in Extracellular Matrix Composition Orchestrate the Fibrotic Feedback Loop Through Macrophage Activation in Dupuytren's Contracture., PMID:40243889
Microarray analysis of the effects of Acthar Gel versus methylprednisolone in a model of focal segmental glomerulosclerosis in female rats., PMID:40223398
Identification of potential drug targets for pelvic organ prolapse using a proteome-wide Mendelian randomization approach., PMID:40064973
Proteomic analysis emphasizes the adaptation of energy metabolism in horses during endurance races., PMID:39955578
Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage., PMID:39863929
Detecting respiratory impairment in newly diagnosed rheumatoid arthritis by MRC dyspnoea scale and microfibrillar-associated protein 4., PMID:39839254
Aloe vera and the Proliferative Phase of Cutaneous Wound Healing: Status Quo Report on Active Principles, Mechanisms, and Applications., PMID:39566518
Identification of potential hub genes associated with recurrent miscarriage through combined transcriptomic and proteomic analysis., PMID:39508749
Microfibrillar-associated protein 4 as a predictive biomarker of treatment response in patients with chronic inflammatory diseases initiating biologics: secondary analyses based on the prospective BELIEVE cohort study., PMID:39465398
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer., PMID:39385083
FOXF1 inhibits invasion and metastasis of lung adenocarcinoma cells and enhances anti-tumor immunity via MFAP4/FAK signal axis., PMID:39271782
The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis., PMID:39256796
Novel Insights into the Aortic Mechanical Properties of Mice Modeling Hereditary Aortic Diseases., PMID:38950604
Identification of novel therapeutic targets for chronic kidney disease and kidney function by integrating multi-omics proteome with transcriptome., PMID:38898508
Microfibril-associated glycoprotein 4 forms octamers that mediate interactions with elastogenic proteins and cells., PMID:38740766
Identification of potential targetable genes in papillary, follicular, and anaplastic thyroid carcinoma using bioinformatics analysis., PMID:38676768
MFAP4-Deficiency Aggravates Age-Induced Changes in Resistance Artery Structure, While Ameliorating Hypertension., PMID:38563153
Rosemary extract and rosmarinic acid accelerate elastic fiber formation by increasing the expression of elastic fiber components in dermal fibroblasts., PMID:38470170
Identifying OGN as a Biomarker Covering Multiple Pathogenic Pathways for Diagnosing Heart Failure: From Machine Learning to Mechanism Interpretation., PMID:38397416
Identification and verification of feature biomarkers associated with immune cells in recurrent pregnancy loss., PMID:38305600
Integrating single-cell and bulk transcriptomic analyses to develop a cancer-associated fibroblast-derived biomarker for predicting prognosis and therapeutic response in breast cancer., PMID:38235137
Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development., PMID:38225249
Identification of tumor-suppressor genes in lung squamous cell carcinoma through integrated bioinformatics analyses., PMID:38188687
Role and new insights of microfibrillar-associated protein 4 in fibrotic diseases., PMID:37957836
Mfap4: a promising target for enhanced liver regeneration and chronic liver disease treatment., PMID:37935709
Presence of microfibril associated glycoprotein 4 and type V collagen and the possible absence of fibrillin-1 in bead-like structures in elastofibroma., PMID:37880056
Microfibrillar-associated protein 4 as a potential marker of acute relapse in inflammatory demyelinating diseases of the central nervous system: Pathological and clinical aspects., PMID:37830484
Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines., PMID:37623890
Circulating biomarkers associated with aortic diameter in male and female patients with thoracic aortic disease: a cross-sectional study., PMID:37385730
Serum MFAP4, a novel potential biomarker for liver cirrhosis screening, correlates with transient elastography in NAFLD patients., PMID:36968563
Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy., PMID:36860278
Integrated analysis of RNA-seq in hepatocellular carcinoma reveals competing endogenous RNA network composed of circRNA, lncRNA, and mRNA., PMID:36827016
Immune-based prognostic biomarkers associated with metastasis of osteosarcoma., PMID:36705300
Declined plasma microfibrillar-associated protein 4 levels in acute coronary syndrome., PMID:36650606
Tumor-suppressive role of microfibrillar associated protein 4 and its clinical significance as prognostic factor and diagnostic biomarker in hepatocellular carcinoma., PMID:36647950
The role of the cd99l2 gene on leukocyte interstitial migration in zebrafish., PMID:36384956
Five immune-related genes as diagnostic markers for endometriosis and their correlation with immune infiltration., PMID:36277723
Secretomics Alterations and Astrocyte Dysfunction in Human iPSC of Leukoencephalopathy with Vanishing White Matter., PMID:36198922
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts., PMID:35920332
MFAP4-Mediated Effects in Elastic Fiber Homeostasis, Integrin Signaling and Cancer, and Its Role in Teleost Fish., PMID:35805199
The Value of the Stemness Index in Ovarian Cancer Prognosis., PMID:35741755
Microfibrillar-associated protein 4 in health and disease., PMID:35644509
Preparing sequencing grade RNAs from a small number of FACS-sorted larvae macrophages isolated from enzyme free dissociated zebrafish larvae., PMID:35342722
Synergistic effect of Aloe vera flower and Aloe gel on cutaneous wound healing targeting MFAP4 and its associated signaling pathway: In-vitro study., PMID:35182666
Erratum corrige: Increased serum levels of microfibrillar-associated protein 4 (MFAP4) are not associated with clinical synovitis in rheumatoid arthritis but may reflect underlying cardiovascular comorbidity., PMID:35088690
[The role of extracellular matrix in the regeneration of motor nerves]., PMID:34878386
MFAP4 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Through Regulation of Macrophage Infiltration and Activity., PMID:34805319
For research use only. Not for human or drug use.
