Catalog No.
YHF07301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu6-Val162
Predicted molecular weight
20.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55001
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAGP, Microfibril-associated glycoprotein 1, MAGP-1, MFAP-2, Microfibrillar-associated protein 2, MAGP1, MFAP2
Hepatic stellate cell-derived microfibrillar-associated protein 2 prevents liver fibrosis by regulating extracellular matrix and inflammation., PMID:40213670
FOXA1-mediated transcription of MFAP2 facilitates cell growth, metastasis and cisplatin resistance in uterine corpus endometrial carcinoma., PMID:40153018
MFAP2 promotes the malignant progression of gastric cancer via activating the PI3K/AKT signaling pathway., PMID:40131129
Mendelian randomization identifies proteins involved in neurodegenerative diseases., PMID:40037332
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis., PMID:39972314
HHIP protein interactions in lung cells provide insight into COPD pathogenesis., PMID:39945347
TWIST1 Regulates FOXM1/β-Catenin to Promote the Growth, Migration, and Invasion of Ovarian Cancer Cells by Activating MFAP2., PMID:39829397
Zonulopathies as Genetic Disorders of the Extracellular Matrix., PMID:39766898
MFAP2 upregulation promotes ESCC metastasis via FAK-AKT signaling pathway., PMID:39698924
Reprogramming of iPSCs to NPCEC-like cells by biomimetic scaffolds for zonular fiber reconstruction., PMID:39697240
MFAP2 induces epithelial-mesenchymal transformation of osteosarcoma cells by activating the Notch1 pathway., PMID:38988940
OIP5-AS1/miR-455-3p/microfibril-associated protein 2 axis exacerbates the progression of thyroid carcinoma., PMID:38988919
The potent potential of MFAP2 in prognosis and immunotherapy of triple-negative breast cancer., PMID:38822944
The use of MFAP2 for diagnosis, prognosis and immunotherapy of triple-negative breast cancer., PMID:38715831
HHIP protein interactions in lung cells provide insight into COPD pathogenesis., PMID:38617310
The construction and validation of ECM-related prognosis model in laryngeal squamous cell carcinoma., PMID:37809868
MFAP2 promotes HSCs activation through FBN1/TGF-β/Smad3 pathway., PMID:37635348
MFAP2 promotes the progression of oral squamous cell carcinoma by activating the Wnt/β-catenin signaling pathway through autophagy., PMID:37592847
The possible molecular mechanism underlying the involvement of the variable shear factor QKI in the epithelial-mesenchymal transformation of oesophageal cancer., PMID:37428781
TWIST1 Promotes Colorectal Carcinoma Stemness and Oxaliplatin Resistance by Activating Microfibrillar-Associated Protein 2., PMID:37428562
Identification and validation of crucial lnc-TRIM28-14 and hub genes promoting gastric cancer peritoneal metastasis., PMID:36690975
MFAP2, upregulated by m1A methylation, promotes colorectal cancer invasiveness via CLK3., PMID:36583532
The role of microfibrillar-associated protein 2 in cancer., PMID:36530974
Microfibril-associated protein 2 is activated by POU class 2 homeobox 1 and promotes tumor growth and metastasis in tongue squamous cell carcinoma., PMID:36527580
Microfibrillar-associated protein 2 is a prognostic marker that correlates with the immune microenvironment in glioma., PMID:36204318
MFAP2 aggravates tumor progression through activating FOXM1/β-catenin-mediated glycolysis in ovarian cancer., PMID:35546486
Pan-Cancer Analysis of Microfibrillar-Associated Protein 2 (MFAP2) Based on Bioinformatics and qPCR Verification., PMID:35211173
Development and Validation of a Novel Prognosis Prediction Model for Patients With Stomach Adenocarcinoma., PMID:35004767
Identification of Differentially Expressed Genes Reveals BGN Predicting Overall Survival and Tumor Immune Infiltration of Gastric Cancer., PMID:34868341
Long non-coding RNA-KCNQ1OT1 mediates miR-423-5p/microfibril-associated protein 2 axis in colon adenocarcinoma., PMID:34704601
Upregulation of microfibrillar-associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma., PMID:34466151
Decreased Levels of Microfibril-Associated Glycoprotein (MAGP)-1 in Patients with Colon Cancer and Obesity Are Associated with Changes in Extracellular Matrix Remodelling., PMID:34445187
Genome-Scale Analysis Identified NID2, SPARC, and MFAP2 as Prognosis Markers of Overall Survival in Gastric Cancer., PMID:33758160
A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord., PMID:33412105
MFAP2 is a Potential Diagnostic and Prognostic Biomarker That Correlates with the Progression of Papillary Thyroid Cancer., PMID:33324100
MFAP2 Promotes the Proliferation of Cancer Cells and Is Associated With a Poor Prognosis in Hepatocellular Carcinoma., PMID:33280519
Genetically predicted circulating protein biomarkers and ovarian cancer risk., PMID:33246661
lncRNA LCPAT1 Upregulation Promotes Breast Cancer Progression via Enhancing MFAP2 Transcription., PMID:32791452
Molecular structure and function of microfibrillar-associated proteins in skeletal and metabolic disorders and cancers., PMID:32572962
Microfibril-Associated Protein 2 (MFAP2) Potentiates Invasion and Migration of Melanoma by EMT and Wnt/β-Catenin Pathway., PMID:32464633
Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits., PMID:32442411
MFAP2 is overexpressed in gastric cancer and promotes motility via the MFAP2/integrin α5β1/FAK/ERK pathway., PMID:32054827
Identification of the growth factor-binding sequence in the extracellular matrix protein MAGP-1., PMID:31988245
Integrated profiling identifies SLC5A6 and MFAP2 as novel diagnostic and prognostic biomarkers in gastric cancer patients., PMID:31894266
MFAP2 promotes epithelial-mesenchymal transition in gastric cancer cells by activating TGF-β/SMAD2/3 signaling pathway., PMID:30034240
Studies on sporadic non-syndromic thoracic aortic aneurysms: II. Alterations of extra-cellular matrix components and focal adhesion proteins., PMID:29708036
Contribution of metabolic disease to bone fragility in MAGP1-deficient mice., PMID:29519758
Structural and compositional diversity of fibrillin microfibrils in human tissues., PMID:29453284
Proteomic Analysis of the Bovine and Human Ciliary Zonule., PMID:28125844
Simple and rapid characterization of novel large germline deletions in SDHB, SDHC and SDHD-related paraganglioma., PMID:27485256
For research use only. Not for human or drug use.
