Catalog No.
YHF01901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn21-Ser243
Predicted molecular weight
27.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P54108
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cysteine-rich secretory protein 3, SGP28, CRISP-3, CRISP3, Specific granule protein of 28 kDa
CRISP3-PSP94 complex regulates P2RX7 mediated signalling in prostate cancer cells and macrophages via CITED2., PMID:40473221
The epididymis contributes to sperm DNA integrity and early embryo development through Cysteine-Rich Secretory Proteins., PMID:40293787
Upregulation of CRISP3 and its clinical values in adult sepsis: a comprehensive analysis based on microarrays and a two-retrospective-cohort study., PMID:39624089
Alpha-1-B glycoprotein (A1BG) inhibits sterol-binding and export by CRISP2., PMID:39433128
Characterizing the Impact of Dysregulated Micrornas on CRISP3 Isoforms in Male Infertility., PMID:39407057
Computational insights into CRISP3 downregulation in cervical cancer and its cervical lineages pattern., PMID:39139989
Multi-omics landscapes reveal heterogeneity in long COVID patients characterized with enhanced neutrophil activity., PMID:39135185
EP300 promotes tumor stemness via epigenetic activation of CRISP3 leading to lobaplatin resistance in triple-negative breast cancer., PMID:38879857
Detection of Protein Biomarkers Relevant to Sperm Characteristics and Fertility in Semen in Three Wild Felidae: The Flat-Headed Cat (Prionailurus planiceps), Fishing Cat (Prionailurus viverrinus), and Asiatic Golden Cat (Catopuma temminckii)., PMID:38612267
Bioinformatics identification of characteristic genes of cervical cancer via an artificial neural network., PMID:38453655
Semen Protein CRISP3 Promotes Reproductive Performance of Boars through Immunomodulation., PMID:38396941
The role of equine seminal plasma derived cysteine rich secretory protein 3 (CRISP3) in the interaction between polymorphonuclear neutrophils (PMNs) and populations of viable or dead spermatozoa, and bacteria., PMID:38377715
Gene expression in multiple sclerosis during pregnancy based on integrated bioinformatics analysis., PMID:38154347
Down Regulation of EGF and AZGP1 Were Associated with Clinical Characteristics in Chronic Rhinosinusitis with Nasal Polyps: An Observation Study., PMID:37920240
Transcriptomic comparison of bone marrow CD34 + cells and peripheral blood neutrophils from ET patients with JAK2 or CALR mutations., PMID:37550636
Binding of Equine Seminal Lactoferrin/Superoxide Dismutase (SOD-3) Complex Is Biased towards Dead Spermatozoa., PMID:36611662
Integrated analyses reveal evolutionarily conserved and specific injury response genes in dorsal root ganglion., PMID:36323676
Unravelling of the comparative Transcriptomic Profile of Gallbladder Cancer using mRNA sequencing., PMID:35469389
A Combined CRISP3 and SPINK1 Prognostic Grade in EPS-Urine and Establishment of Models to Predict Prognosis of Patients With Prostate Cancer., PMID:35252264
Prostate secretory protein 94 inhibits sterol binding and export by the mammalian CAP protein CRISP2 in a calcium-sensitive manner., PMID:35063506
Conceptus interferon gamma is essential for establishment of pregnancy in the pig†., PMID:34608481
Differential gene expression and network-based analyses of the placental transcriptome reveal distinct potential biomarkers for gestationaldiabetes mellitus., PMID:34530062
LINC01342 silencing upregulates microRNA-508-5p to inhibit progression of lung cancer by reducing cysteine-rich secretory protein 3., PMID:34504061
CRISP protein expression in semen of the endangered Malayan tapir (Tapirus indicus)., PMID:34153566
Screening differentially expressed proteins of coronary heart disease with congenital cold syndrome based on tandem mass tag (TMT) technology., PMID:33904367
Discovery and validation of novel biomarkers for detection of cervical cancer., PMID:33624385
MiR-182-5p, MiR-192-5p, and MiR-493-5p Constitute a Regulatory Network with CRISP3 in Seminal Plasma Fluid of Teratozoospermia Patients., PMID:33620707
Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility., PMID:33037689
Equine seminal plasma and sperm membrane: Functional proteomic assessment., PMID:32679458
Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals., PMID:32513118
CRISP3 expression drives prostate cancer invasion and progression., PMID:32357309
Analysis of potential hub genes involved in the pathogenesis of Chinese type 1 diabetic patients., PMID:32355739
Muscular atrophy, impaired epithelial autophagy and UCHL1 increase in androgen-deficient cauda epididymis., PMID:32191915
Upregulation of CRISP-3 and kallikrein in stallion seminal plasma is associated with poor tolerance of cooled storage., PMID:31965650
Relevance of CRISP proteins for epididymal physiology, fertilization, and fertility., PMID:31218833
Caught in a Trap? Proteomic Analysis of Neutrophil Extracellular Traps in Rheumatoid Arthritis and Systemic Lupus Erythematosus., PMID:30915077
Zinc binding regulates amyloid-like aggregation of GAPR-1., PMID:30700571
Low expression of CRISP3 predicts a favorable prognosis in patients with mammary carcinoma., PMID:30609035
Astrocyte elevated gene-1 induces autophagy in diabetic cardiomyopathy through upregulation of KLF4., PMID:30520133
Crystal structure of the complex between venom toxin and serum inhibitor from Viperidae snake., PMID:30504218
Positive Selection in the Evolution of Mammalian CRISPs., PMID:30370448
Cysteine-rich secretory protein 3: inflammation role in adult varicocoele., PMID:30354034
Relationship of cysteine-rich secretory protein-3 gene and protein with semen quality in stallions., PMID:30099787
In silico analysis identifies CRISP3 as a potential peripheral blood biomarker for multiple myeloma: From data modeling to validation with RT-PCR., PMID:29552153
Androgen receptor mediated epigenetic regulation of CRISP3 promoter in prostate cancer cells., PMID:29477539
Tracing the Evolutionary History of the CAP Superfamily of Proteins Using Amino Acid Sequence Homology and Conservation of Splice Sites., PMID:29071358
Association of the cysteine-rich secretory protein-3 (CRISP-3) and some of its polymorphisms with the quality of cryopreserved stallion semen., PMID:28855043
RNA-Seq analysis of peripheral blood mononuclear cells reveals unique transcriptional signatures associated with disease progression in dengue patients., PMID:28683259
Cervical mucus proteome in endometriosis., PMID:28174513
Combined serum and EPS-urine proteomic analysis using iTRAQ technology for discovery of potential prostate cancer biomarkers., PMID:28009970
For research use only. Not for human or drug use.
