Catalog No.
YHF01201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn444-Val500
Predicted molecular weight
8.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P53985
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MCT 1, SLC16A1, Monocarboxylate transporter 1, MCT1, Solute carrier family 16 member 1
Transmembrane Protease Serine 11B Modulates Lactate Transport Through SLC16A1 in Pancreatic Ductal Adenocarcinoma-A Functional Link to Phenotype Heterogeneity., PMID:40508207
Ion Channel-Extracellular Matrix Interplay in Colorectal Cancer: A Network-Based Approach to Tumor Microenvironment Remodeling., PMID:40507957
The lactylation-immune regulatory axis: a potential therapeutic target for migraine prevention and treatment., PMID:40468199
SLC16A1 Inhibits Ferroptosis and Promotes the Progression of Head and Neck Squamous Cell Carcinoma., PMID:40302798
Exploring the Molecular Intersection of Posterior Ocular Tuberculosis: Mycobacterium tuberculosis Proteins, Ocular Autoimmunity, and Immune Receptor Interactions., PMID:40151358
Lactate metabolic coupling between the endplates and nucleus pulposus via MCT1 is essential for intervertebral disc health., PMID:40060488
Lactate dehydrogenase B deficiency-dependent hyperlactatemia coordinates with necroptosis to worsen septic liver and kidney injuries., PMID:40043615
Structural and molecular dysfunctions in granulosa cells: A key contributor to porcine follicular atresia., PMID:40043493
Lactate metabolism in clonal plasma cells and its therapeutic implications in multiple myeloma patients with elevated serum LDH levels., PMID:39948621
Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid-liquid phase separation-related genes., PMID:39915583
Association Between Genetically Proxied SLC12A2 Inhibition and Inflammatory Bowel Disease: A Mendelian Randomization Study., PMID:39913044
The association of SLC16A1 (MCT1) gene polymorphism with body composition changes during weight loss interventions: A randomized trial with sex-dependent analysis., PMID:39787575
Hypoglycaemia following physical exercise in a patient with novel SLC16A1 variant., PMID:39715334
Genetic and non-genetic factors influencing the therapeutic response of valproic acid in pediatric epileptic patients., PMID:39711059
Isolation method of brain microvessels from small frozen human brain tissue for blood-brain barrier protein expression analysis., PMID:39702171
LncRNA SLC16A1-AS1 participates in the initiation and progression of colorectal cancer by regulating MAP3K9 expression through targeting miR-515-5p., PMID:39659936
YTHDF1 boosts the lactate accumulation to potentiate cervical cancer cells immune escape., PMID:39557826
Regulatory Role of eIF2αK4 in Amino Acid Transporter Expression in Mouse Brain Capillary Endothelial Cells., PMID:39532778
Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells., PMID:39532094
Exploring the anticancer mechanism of cardiac glycosides using proteome integral solubility alteration approach., PMID:39350574
Comprehensive transcriptome analysis unravels the perturbated cardiovascular-related molecular mechanisms of tilapia under high-temperature stress., PMID:39298880
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression., PMID:39247822
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation., PMID:39179170
Renshen Yangrong decoction for secondary malaise and fatigue: network pharmacology and Mendelian randomization study., PMID:38966421
Exosomal circSIPA1L3-mediated intercellular communication contributes to glucose metabolic reprogramming and progression of triple negative breast cancer., PMID:38849860
Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinoma., PMID:38817665
Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study., PMID:38809137
lncRNA CDKN2B-AS1 is downregulated in patients with ventricular fibrillation in acute myocardial infarction., PMID:38771854
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis., PMID:38616756
Enhancing the anticancer effect of androgen deprivation therapy by monocarboxylate transporter 1 inhibitor in prostate cancer cells., PMID:38558458
Targeting Metabolic Dependencies Fueling the TCA Cycle to Circumvent Therapy Resistance in Acute Myeloid Leukemia., PMID:38558131
Oncogenic circ-SLC16A1 promotes progression of non-small cell lung cancer via regulation of the miR-1287-5p/profilin 2 axis., PMID:38539084
Metabolic pathways of glucose and fructose: II Spatiotemporal expression of genes involved in synthesis and transport of lactate in ovine conceptuses†., PMID:38531778
The polymorphism T1470A of the SLC16A1 gene is associated with the lactate and ventilatory thresholds but not with fat oxidation capacity in young men., PMID:38216723
A systemic analysis of monocarboxylate transporters in ovarian cancer and possible therapeutic interventions., PMID:37934721
Upregulation of BMP1 through ncRNAs correlates with adverse outcomes and immune infiltration in clear cell renal cell carcinoma., PMID:37848987
Differential expression of mRNA 3'-end isoforms in cervical and ovarian cancers., PMID:37810050
Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary nonfunction of fatty liver allografts., PMID:37722450
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors., PMID:37516113
Expression analysis of BACH1 with clinical variables using the US breast cancer patient cohort., PMID:37461502
Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries., PMID:37353852
A novel mutation in the KCNJ11 gene (p.Val36Glu), predisposes to congenital hyperinsulinemia., PMID:37336273
Construction of SLC16A1/3 Targeted Gallic Acid-Iron-Embelin Nanoparticles for Regulating Glycolysis and Redox Pathways in Cervical Cancer., PMID:37307591
Differential effect of lactate on synovial fibroblast and macrophage effector functions., PMID:37304267
Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome., PMID:37283406
Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review., PMID:36982217
Monocarboxylate transporter 1 in the liver modulates high-fat diet-induced obesity and hepatic steatosis in mice., PMID:36933792
Comprehensive analysis of pan-cancer reveals the potential of SLC16A1 as a prognostic and immunological biomarker., PMID:36930112
The hsa_circ_0000276-ceRNA regulatory network and immune infiltration in cervical cancer., PMID:36894874
Interaction between Butyrate and Tumor Necrosis Factor α in Primary Rat Colonocytes., PMID:36830627
For research use only. Not for human or drug use.
