Catalog No.
YHF00401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg88-Ala332
Predicted molecular weight
30.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P53779
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAPK10, Mitogen-activated protein kinase 10, Stress-activated protein kinase 1b, c-Jun N-terminal kinase 3, Stress-activated protein kinase JNK3, MAP kinase 10, MAP kinase p49 3F12, JNK3, SAPK1B, PRKM10, MAPK 10, SAPK1b, JNK3A
TW-7 Alleviate Apoptosis of Embryos Derived From Vitrified MII Oocytes by Downregulation of JNK Signaling in Mice., PMID:40497346
Exploring the mechanisms of artemisinin and its derivatives in the treatment of atopic dermatitis based on network pharmacology and molecular docking: A review., PMID:40355181
The impact of leptin receptor (LepR) mutation on the development of MASLD in a murine model., PMID:40339770
Functional Specificity of Astrocyte Subtypes in Alzheimer's Disease: Decoding Disease Mechanisms Through Network-based Analysis of Integrated Single-Nuclei Multi-Omic Data., PMID:40301248
Exploring Mechanisms of Ephx2 in Treating Atherosclerosis Using Independent Cascade Model and Adverse Outcome Pathways., PMID:40151075
Unraveling the Mechanism of the Endophytic Bacterial Strain Pseudomonas oryzihabitans GDW1 in Enhancing Tomato Plant Growth Through Modulation of the Host Transcriptome and Bacteriome., PMID:40076548
Metabolomics and network pharmacology-based identification of phenolic acids in Polygonatum kingianum var. grandifolium rhizomes as anti-cancer/Tumor active ingredients., PMID:39689118
Expression characteristics of miR-222b-5p/MAPK10 in major immune organs of SPF chickens infected with avian reticuloendotheliosis virus strain SNV (REV-SNV)., PMID:39675224
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
Transcriptome profiling of Canine Parvovirus 2 Nonstructural gene 1(CPV2.NS1) transfected 4T1 mice mammary tumor cells to elucidate its oncolytic effects., PMID:39419151
Berberine modulates ovarian cancer autophagy and glycolysis through the LINC01123/P65/MAPK10 signaling axis., PMID:39395322
Molecular profiling of a rat model of vascular dementia: Evidences from proteomics, metabolomics and experimental validations., PMID:39341485
A cholinergic signaling pathway underlying cortical circuit activation of quiescent neural stem cells in the lateral ventricle., PMID:39316665
A cheminformatics and network pharmacology approach to elucidate the mechanism of action of Mycobacterium tuberculosis γ-carbonic anhydrase inhibitors., PMID:39286631
IRE1/JNK Is the Leading UPR Pathway in 6-OHDA-Induced Degeneration of Differentiated SH-SY5Y Cells., PMID:39062922
CircPGM5 regulates Foxo3a phosphorylation via MiR-21-5p/MAPK10 axis to inhibit bladder cancer progression., PMID:39004326
Inhibition of Prolactin Affects Epididymal Morphology by Decreasing the Secretion of Estradiol in Cashmere Bucks., PMID:38929397
Reversal of tamoxifen resistance by artemisinin in ER+ breast cancer: bioinformatics analysis and experimental validation., PMID:38827320
Modulation of Ras signaling pathway by exosome miRNAs in T-2 toxin-induced chondrocyte injury., PMID:38825033
[Molecular mechanisms of the effect of standardized placental hydrolysate peptides on mitochondria functioning]., PMID:38785053
Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification., PMID:38675723
Identification of circadian rhythm-related gene classification patterns and immune infiltration analysis in heart failure based on machine learning., PMID:38509983
Genetic alterations in the neuronal development genes are associated with changes of the tumor immune microenvironment in pancreatic cancer., PMID:38495381
Surveying the landscape of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data., PMID:38405825
Hub genes, key miRNAs and interaction analyses in type 2 diabetes mellitus: an integrative in silico approach., PMID:38366952
P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis., PMID:38352468
Primary study on the effects and mechanisms of separate and combined decoctions of Scutellaria baicalensis Georgi - Coptis chinensis Franch extracts in relieving acute alcoholic liver injury in rats., PMID:38253276
Molecular Targets and Mechanisms of Hedyotis diffusa Willd. for Esophageal Adenocarcinoma Treatment Based on Network Pharmacology and Weighted Gene Co-expression Network Analysis., PMID:38213161
Interleukin-7 potentiates MAPK10-elicited host-protective vaccine against Leishmania donovani., PMID:38134556
MiR-223-3p overexpressed adipose mesenchymal stem cell-derived exosomes promote wound healing via targeting MAPK10., PMID:37837832
Red Kale (Brassica oleracea L. ssp. acephala L. var. sabellica) Induces Apoptosis in Human Colorectal Cancer Cells In Vitro., PMID:37836781
Differentially Expressed mRNA in Streptozotocin-Induced Diabetic Bladder Using RNA Sequencing Analysis., PMID:37798882
Gene-diet interaction analysis using novel weighted food scores discovers the adipocytokine signaling pathway associated with the development of type 2 diabetes., PMID:37680885
Molecular Mechanism of Berberine in the Treatment of Calcified Aortic Valve Disease Based on AGE-RAGE Signal Pathway., PMID:37652411
RNA-Seq transcriptomic landscape profiling of spontaneously hypertensive rats treated with a sodium-glucose cotransporter 2 (SGLT2) inhibitor., PMID:37572641
Total flavonoids of Hippophae rhamnoides L. improves type 2 diabetes symptoms in rats through down-regulating of the DAG/PRKCA/MAPK10/p65/TNF-α signalling pathway., PMID:37499844
Construction and validation of an oxidative-stress-related risk model for predicting the prognosis of osteosarcoma., PMID:37285835
Baseline clinical, hormonal and molecular markers associated with clinical response to IL-23 antagonism in hidradenitis suppurativa: A prospective cohort study., PMID:36933897
TMT-based proteomics profile reveals changes of the entorhinal cortex in a kainic acid model of epilepsy in mice., PMID:36792025
Genomic comparison of two strains of Mycobacterium avium subsp. paratuberculosis with contrasting pathogenic phenotype., PMID:36587510
Inflammation-related pathways involved in damaged articular cartilage of rats exposed to T-2 toxin based on RNA-sequencing analysis., PMID:36544491
Comprehensive analysis of dysregulated circular RNAs and construction of a ceRNA network involved in the pathology of Alzheimer's disease in a 5 × FAD mouse model., PMID:36466608
Network pharmacology and molecular docking-based analysis of protective mechanism of MLIF in ischemic stroke., PMID:36465453
Keratin 18 Depletion as a Possible Mechanism for the Induction of Apoptosis and Ferroptosis in the Rat Hippocampus After Hypobaric Hypoxia., PMID:36395917
Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome., PMID:36329148
Analysis of the Function of LncRNA-MSTRG.16919.1 in BHV-1-Infected Bovine Kidney Subculture Cells by Transcriptome Sequencing., PMID:36298658
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice., PMID:35941186
Network pharmacology-based analysis and experimental in vitro validation on the mechanism of Paeonia lactiflora Pall. in the treatment for type I allergy., PMID:35879791
Construction of a Novel circRNA/miRNA/mRNA Regulatory Network to Explore the Potential Pathogenesis of Wilson's Disease., PMID:35784724
Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays., PMID:35681650