Catalog No.
YHE95001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr673-Ser903
Predicted molecular weight
27.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52790
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hexokinase-C, Hexokinase type III, HK3, Hexokinase-3, HK III
Baicalin Modulates Glycolysis via the PKC/Raf/MEK/ERK and PI3K/AKT Signaling Pathways to Attenuate IFN-I-Induced Neutrophil NETosis., PMID:40420943
Proteomic profiling reveals a higher presence of glycolytic enzymes in human atherosclerotic lesions with unfavourable histological characteristics., PMID:40354194
Multi-omics analysis reveals immunosuppression in oesophageal squamous cell carcinoma induced by creatine accumulation and HK3 deficiency., PMID:40329370
Heterogeneity of Neutrophils and Immunological Function in Neonatal Sepsis: Analysis of Molecular Subtypes Based on Hypoxia-Glycolysis-Lactylation., PMID:40177399
FSTL3 promotes colorectal cancer by activating the HIF1 pathway., PMID:40154584
Reliable hexokinase 3 protein detection in human cell lines and primary tissue., PMID:40071468
Senescent macrophages trigger a pro-inflammatory program and promote the progression of rheumatoid arthritis., PMID:39904033
Identification of mRNA biomarkers in extremely early hypertensive intracerebral hemorrhage (HICH)., PMID:39616335
Multi-omics analysis provides new insights into mechanism of didymin on non-alcoholic fatty liver disease in rats., PMID:39277989
Diosmetin-7-O-β-D-glucopyranoside from Pogostemonis Herba alleviated SARS-CoV-2-induced pneumonia by reshaping macrophage polarization and limiting viral replication., PMID:39182703
Hexokinase HK3-mediated O-GlcNAcylation of EP300: a key regulator of PD-L1 expression and immune evasion in ccRCC., PMID:39179546
Identification of two key biomarkers CD93 and FGL2 associated with survival of acute myeloid leukaemia by weighted gene co-expression network analysis., PMID:39054581
Single-cell RNA-sequencing of human eosinophils in allergic inflammation in the esophagus., PMID:38871184
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma., PMID:38714539
Genetic association of novel SNPs in HK-1 (rs201626997) and HK-3 (rs143604141) with type 2 diabetes mellitus in Bangladeshi population., PMID:38527673
Identification of HK3 as a promising immunomodulatory and prognostic target in sepsis-induced acute lung injury., PMID:38484574
Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis., PMID:38427757
Milk proteomic analysis reveals differentially expressed proteins in high-yielding and low-yielding Guanzhong dairy goats at peak lactation., PMID:38415394
Preclinical Development in Radiopharmaceutical Therapy for Prostate Cancer., PMID:37468417
Identification and immunological characterization of cuproptosis-related molecular clusters in idiopathic pulmonary fibrosis disease., PMID:37266442
CircZBTB44 promotes renal carcinoma progression by stabilizing HK3 mRNA structure., PMID:37106446
The lncRNA XIST/miR-29b-3p/COL3A1 axis regulates central carbon metabolism in head and neck squamous cell carcinoma and is associated with poor tumor prognosis., PMID:36923098
Bioinformatic analysis of underlying mechanisms of Kawasaki disease via Weighted Gene Correlation Network Analysis (WGCNA) and the Least Absolute Shrinkage and Selection Operator method (LASSO) regression model., PMID:36829193
Metabolic heterogeneity in early-stage lung adenocarcinoma revealed by RNA-seq and scRNA-seq., PMID:36692643
Identification of novel immune-related targets mediating disease progression in acute pancreatitis., PMID:36590588
Necroptosis-related subtypes are associated with bronchiectasis in pulmonary non-tuberculous mycobacteria-infected patients: a perspective based on transcriptomic analysis., PMID:36469164
METTL3 boosts glycolysis and cardiac fibroblast proliferation by increasing AR methylation., PMID:36370857
Zishen Pill alleviates diabetes in Db/db mice via activation of PI3K/AKT pathway in the liver., PMID:36352450
Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels., PMID:35943566
Zelkovamycins F and G, Cyclopeptides with Cα-Methyl-threonine Residues, from an Endophytic Kitasatospora sp., PMID:35715218
Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions., PMID:35538058
Identification of Key Pathways and Establishment of a Seven-Gene Prognostic Signature in Cervical Cancer., PMID:35154316
Prioritization of putatively detrimental variants in euploid miscarriages., PMID:35132093
Identification of Tumor Antigens and Immune Landscape in Glioblastoma for mRNA Vaccine Development., PMID:34527020
Identification of Blood-Based Glycolysis Gene Associated with Alzheimer's Disease by Integrated Bioinformatics Analysis., PMID:34308907
Comprehensive Analysis of Monocarboxylate Transporter 4 (MCT4) expression in breast cancer prognosis and immune infiltration via integrated bioinformatics analysis., PMID:34269158
A host transcriptomic signature for identification of respiratory viral infections in the community., PMID:34120332
Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis., PMID:33949285
Identification of a Novel Glycolysis-Related Gene Signature Correlates With the Prognosis and Therapeutic Responses in Patients With Clear Cell Renal Cell Carcinoma., PMID:33816274
Glycolysis-Related Genes Serve as Potential Prognostic Biomarkers in Clear Cell Renal Cell Carcinoma., PMID:33564363
Regulation of glycolytic genes in human macrophages by oxysterols: a potential role for liver X receptors., PMID:33377180
Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma., PMID:33239635
An eleven metabolic gene signature-based prognostic model for clear cell renal cell carcinoma., PMID:33221754
Crucial transcripts predict response to initial immunoglobulin treatment in acute Kawasaki disease., PMID:33082496
Integrative Network Fusion: A Multi-Omics Approach in Molecular Profiling., PMID:32714870
Altered Gene Expression Profiles in Peripheral Blood Mononuclear Cells in Obese Subjects., PMID:32544907
Bioactive Compounds from Abelmoschus manihot L. Alleviate the Progression of Multiple Myeloma in Mouse Model and Improve Bone Marrow Microenvironment., PMID:32099399
Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors., PMID:31806771
Quantitative proteomics reveals proteins involved in the progression from non-cancerous lesions to gastric cancer., PMID:30048774
Toll-like Receptor 4-Induced Glycolytic Burst in Human Monocyte-Derived Dendritic Cells Results from p38-Dependent Stabilization of HIF-1α and Increased Hexokinase II Expression., PMID:30037846
For research use only. Not for human or drug use.
