Recombinant Human ARHGDIB Protein, N-His

Catalog No.

YHE92401

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Thr2-Glu201

Predicted molecular weight

25.17 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P52566

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

ARHGDIB, Rho-GDI beta, Rho GDP-dissociation inhibitor 2, RAP1GN1, Rho GDI 2, GDIA2, GDID4, Ly-GDI

RhoGDIβ inhibition via miR-200c/AUF1/SOX2/miR-137 axis contributed to lncRNA MEG3 downregulation-mediated malignant transformation of human bronchial epithelial cells., PMID:38376344

Hyperglycemic Stress Induces Expression, Degradation, and Nuclear Association of Rho GDP Dissociation Inhibitor 2 (RhoGDIβ) in Pancreatic β-Cells., PMID:38334664

Proteomic analyses identify HK1 and ATP5A to be overexpressed in distant metastases of lung adenocarcinomas compared to matched primary tumors., PMID:38016997

A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications., PMID:37700323

The Dual Function of RhoGDI2 in Immunity and Cancer., PMID:36835422

PD-L1 enhances migration and invasion of trophoblasts by upregulating ARHGDIB via transcription factor PU.1., PMID:36138021

Novel Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Uncovered by Data-Independent Acquisition Mass Spectrometry., PMID:35939567

Screening anlotinib responders via blood-based proteomics in non-small cell lung cancer., PMID:35867072

SARS-CoV-2 mRNA vaccination is not associated with the induction of anti-HLA or non-HLA antibodies., PMID:35835296

Comprehensive analysis of miRNA-mRNA regulatory network and potential drugs in chronic chagasic cardiomyopathy across human and mouse., PMID:34844599

Prognosis biomarker and potential therapeutic target CRIP2 associated with radiosensitivity in NSCLC cells., PMID:34773852

Inflammatory and immune-related factor Caspase 1 contributes to the development of oral lichen planus., PMID:34481194

CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2., PMID:34437633

A methylation-driven gene panel predicts survival in patients with colon cancer., PMID:34184409

Comparison of Two Strategies to Generate Antigen-Specific Human Monoclonal Antibodies: Which Method to Choose for Which Purpose?, PMID:34017336

KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1., PMID:34006303

Study on the transcriptome for breast muscle of chickens and the function of key gene RAC2 on fibroblasts proliferation., PMID:33676413

Causes of Positive Pretransplant Crossmatches in the Absence of Donor-Specific Anti-Human Leukocyte Antigen Antibodies: A Single-Center Experience., PMID:33536364

ARHGDIB and AT1R autoantibodies are differentially related to the development and presence of chronic antibody-mediated rejection and fibrosis in kidney allografts., PMID:33358038

Systematic investigation of biomarker-like role of ARHGDIB in breast cancer., PMID:32176626

Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression., PMID:32109988

Antibodies Against ARHGDIB and ARHGDIB Gene Expression Associate With Kidney Allograft Outcome., PMID:31651716

RhoGDI stability is regulated by SUMOylation and ubiquitination via the AT1 receptor and participates in Ang II-induced smooth muscle proliferation and vascular remodeling., PMID:31362179

Anti-D4GDI antibodies activate platelets in vitro: a possible link with thrombocytopenia in primary antiphospholipid syndrome., PMID:31262358

Antibodies against ARHGDIB are associated with long-term kidney graft loss., PMID:31194283

ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability., PMID:31016112

Proteomic characterization of early lung response to breast cancer metastasis in mice., PMID:30763573

Podocytes and autophagy: a potential therapeutic target in lupus nephritis., PMID:30755075

Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway., PMID:30192158

Unconventional myosin VIIA promotes melanoma progression., PMID:29361540

Genome-wide association study identified copy number variants associated with sporadic colorectal cancer risk., PMID:29079706

Increased dermal collagen bundle alignment in systemic sclerosis is associated with a cell migration signature and role of Arhgdib in directed fibroblast migration on aligned ECMs., PMID:28662216

Characterizing isomiR variants within the microRNA-34/449 family., PMID:28192603

Therapeutic effects of Euphorbia Pekinensis and Glycyrrhiza glabra on Hepatocellular Carcinoma Ascites Partially Via Regulating the Frk-Arhgdib-Inpp5d-Avpr2-Aqp4 Signal Axis., PMID:28165501

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor Ly-GDI in platelet function: a spatial systems approach., PMID:28148498

Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis., PMID:26732727

An adventitious interaction of filamin A with RhoGDI2(Tyr153Glu)., PMID:26707877

Screening and identification of five serum proteins as novel potential biomarkers for cured pulmonary tuberculosis., PMID:26499913

Protective Role of Rho Guanosine Diphosphate Dissociation Inhibitor, Ly-GDI, in Pulmonary Alveolitis., PMID:26469087

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity., PMID:26414765

Autoantibodies specific to D4GDI modulate Rho GTPase mediated cytoskeleton remodeling and induce autophagy in T lymphocytes., PMID:25623267

Overexpression of RhoGDI2 correlates with the progression and prognosis of pancreatic carcinoma., PMID:25573518

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer., PMID:25516960

Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses., PMID:25454514

Differential expression patterns of metastasis suppressor proteins in basal cell carcinoma., PMID:25428551

RNA interference-mediated knockdown of RhoGDI2 induces the migration and invasion of human lung cancer A549 cells via activating the PI3K/Akt pathway., PMID:25266803

Rho GDP dissociation inhibitor beta promotes cell proliferation and invasion by modulating the AKT pathway in hepatocellular carcinoma., PMID:25180836

TAT-RhoGDI2, a novel tumor metastasis suppressor fusion protein: expression, purification and functional evaluation., PMID:25142698

Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines., PMID:25086928

Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays., PMID:25073739

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