Catalog No.
YHE84101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn52-His258
Predicted molecular weight
25.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P51610
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CFF, VCAF, HCFC1, HCF-1, HCF1, HFC1, C1 factor, HCF, VP16 accessory protein, Host cell factor 1
CXXC5 is a ubiquitinated protein and is degraded by the ubiquitin-proteasome pathway., PMID:40371716
Candida albicans biofilm extracellular vesicles deliver candidalysin to epithelial cell membranes and induce host cell responses., PMID:40172491
RONIN/HCF1-TFEB Axis Protects Against D-Galactose-Induced Cochlear Hair Cell Senescence Through Autophagy Activation., PMID:39985193
Fucoidan alginate and sulfated alginate microbeads induce distinct coagulation, inflammatory and fibrotic responses., PMID:39896282
The inactivation of the Niemann Pick C1 cholesterol transporter restricts SARS-CoV-2 entry into host cells by decreasing ACE2 abundance at the plasma membrane., PMID:39707537
HSP90 N-terminal inhibition promotes mitochondria-derived vesicles related metastasis by reducing TFEB transcription via decreased HSP90AA1-HCFC1 interaction in liver cancer., PMID:39461872
Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway., PMID:39365288
Bioinformatics analysis of the role of RNA modification regulators in polycystic ovary syndrome., PMID:39281527
Identification of a Polypeptide Inhibitor of O-GlcNAc Transferase with Picomolar Affinity., PMID:39276112
Histone demethylase KDM2A recruits HCFC1 and E2F1 to orchestrate male germ cell meiotic entry and progression., PMID:39160277
Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions., PMID:39126650
O-GlcNAcylation determines the function of the key O-GalNAc glycosyltransferase C1GalT1 in bladder cancer., PMID:39126245
The CD28 IVS3 + 17 T/C polymorphism and the GVHD occurrence in Tunisian patients receiving an HLA-identical sibling HSCs transplant., PMID:39084099
Variants in HCFC1 and MN1 genes causing intellectual disability in two Pakistani families., PMID:38956580
Dissecting OGT's TPR domain to identify determinants of cellular function., PMID:38768345
HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription., PMID:38670996
Overexpression of MMACHC Prevents Craniofacial Phenotypes Caused by Knockdown of znf143b., PMID:38617190
Identification of a chromatin-bound ERRα interactome network in mouse liver., PMID:38537884
Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway., PMID:38168435
Literature-Based Discovery to Elucidate the Biological Links between Resistant Hypertension and COVID-19., PMID:37759668
Comparative transcriptional analysis between virulent isolate HN1307 and avirulent isolate GD1108 of grass carp reovirus genotype II., PMID:37451563
Upregulation of HCFC1 expression promoted hepatocellular carcinoma progression through inhibiting cell cycle arrest and correlated with immune infiltration., PMID:37283799
HCFC1 variants in the proteolysis domain are associated with X-linked idiopathic partial epilepsy: Exploring the underlying mechanism., PMID:37264743
Identification of key genes and molecular pathways in type 2 diabetes mellitus and polycystic ovary syndrome via bioinformatics analyses., PMID:37140276
APOC1 predicts a worse prognosis for esophageal squamous cell carcinoma and is associated with tumor immune infiltration during tumorigenesis., PMID:36969562
Missense and nonsense mutations of the zebrafish hcfc1a gene result in contrasting mTor and radial glial phenotypes., PMID:36804358
Deletion of the Transcriptional Coactivator HCF-1 In Vivo Impairs the Removal of Repressive Heterochromatin from Latent HSV Genomes and Suppresses the Initiation of Viral Reactivation., PMID:36692302
Genomic Profiling Reveals the Variant Landscape of Sporadic Parathyroid Adenomas in Chinese Population., PMID:36611251
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells., PMID:36553506
MS-proteomics provides insight into the host responses towards alginate microspheres., PMID:36420052
Associations between Extracellular Matrix Protein 1 Gene Polymorphism and Progression of Liver Disease., PMID:36299684
Clinical characteristics and genotype analysis of five infants with cblX type of methylmalonic acidemia., PMID:36207831
Host factors associated with either VP16 or VP16-induced complex differentially affect HSV-1 lytic infection., PMID:36069169
RNA sequencing reveals dynamic expression of lncRNAs and mRNAs in caprine endometrial epithelial cells induced by Neospora caninum infection., PMID:35999576
Identification and validation of immune related core transcription factors GTF2I in NAFLD., PMID:35891648
The KIR2DL2/HLA-C1C1 Gene Pairing Is Associated With an Increased Risk of SARS-CoV-2 Infection., PMID:35874712
Lpt, trr, and Hcf regulate histone mono- and dimethylation that are essential for Drosophila heart development., PMID:35853502
HIF1 and DROSHA are involved in MMACHC repression in hypoxia., PMID:35636712
Inherited defects of cobalamin metabolism., PMID:35337626
Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis., PMID:35263388
Rare germline heterozygous missense variants in BRCA1-associated protein 1, BAP1, cause a syndromic neurodevelopmental disorder., PMID:35051358
Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy., PMID:35013307
Prenatal diagnosis of combined methylmalonic acidemia and homocystinuria cobalamin C type using clinical exome sequencing and targeted gene analysis., PMID:34655177
Sex-specific differences in plasma levels of FXII, HK, and FXIIa-C1-esterase inhibitor complexes in community-acquired pneumonia., PMID:34318685
The role of HCFC1 in syndromic and non-syndromic intellectual disability., PMID:34164576
Venestatin from parasitic helminths interferes with receptor for advanced glycation end products (RAGE)-mediated immune responses to promote larval migration., PMID:34081755
The dystonia gene THAP1 controls DNA double-strand break repair choice., PMID:33857404
Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis., PMID:33710266
A Glycoprotein Mutation That Emerged during the 2013-2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion., PMID:33593971