Catalog No.
YHE82201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His410-Leu553
Predicted molecular weight
19.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P51511
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MT2MMP, MT2-MMP, MMP15, SMCP-2, MTMMP2, MT-MMP 2, Membrane-type matrix metalloproteinase 2, MMP-15, Membrane-type-2 matrix metalloproteinase, Matrix metalloproteinase-15
Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways., PMID:39919899
Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects., PMID:39812346
MMP-14 Exhibits Greater Expression, Content and Activity Compared to MMP-15 in Human Renal Carcinoma., PMID:39125675
Mendelian randomization analysis identifies druggable genes and drugs repurposing for chronic obstructive pulmonary disease., PMID:38660492
Pkd1l1-deficiency drives biliary atresia through ciliary dysfunction in biliary epithelial cells., PMID:38460793
Magnolin targeting of the JNK/Sp1/MMP15 signaling axis suppresses cervical cancer microenvironment and metastasis via microbiota modulation., PMID:38123014
Matrix metalloproteinases and tissue inhibitors in multiple myeloma: promote or inhibit?, PMID:37823051
[Intervention effects of miR-125b-5p on cognitive dysfunction induced by traumatic brain injury in rats and its mechanisms]., PMID:37088745
Identification of the MMP family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:36941602
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits., PMID:36574455
Matrix metalloproteinase 1 is a poor prognostic biomarker for patients with hepatocellular carcinoma., PMID:36169759
Differential Expression and Localization of ADAMTS Proteinases in Proliferative Diabetic Retinopathy., PMID:36144730
Effect of hydroxychloroquine and chloroquine on syncytial differentiation and autophagy in primary human trophoblasts., PMID:36068776
Cancer cell-derived exosomal miR-425-3p induces white adipocyte atrophy., PMID:35941833
An MMP-based risk score strongly distinguishes prognosis in hepatocellular carcinoma after resection., PMID:35861053
Weighted Gene Co-expression Network Analysis Identifies Specific Modules and Hub Genes Related to Subacute Ruminal Acidosis., PMID:35754546
Tiki proteins are substrates of membrane-type matrix metalloproteinases., PMID:35689492
Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis., PMID:35453827
Asiatic acid from centella asiatica exert anti-invasive ability in human renal cancer cells by modulation of ERK/p38MAPK-mediated MMP15 expression., PMID:35316724
Landscape Analysis of Matrix Metalloproteinases Unveils Key Prognostic Markers for Patients With Breast Cancer., PMID:35069702
Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC)., PMID:35062057
MT2-MMP is differentially expressed in multiple myeloma cells and mediates their growth and progression., PMID:35041985
Bi-allelic null variant in matrix metalloproteinase-15, causes congenital cardiac defect, cholestasis jaundice, and failure to thrive., PMID:34988996
Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells., PMID:34940120
The plasma peptides of Alzheimer's disease., PMID:34182925
Expression gradient of metalloproteinases and their inhibitors from proximal to distal segments of abdominal aortic aneurysm., PMID:34091862
A central role for cAMP/EPAC/RAP/PI3K/AKT/CREB signaling in LH-induced follicular Pgr expression at medaka ovulation†., PMID:33880506
Combining exome/genome sequencing with data repository analysis reveals novel gene-disease associations for a wide range of genetic disorders., PMID:33875846
Silencing LINC00482 inhibits tumor-associated inflammation and angiogenesis through down-regulation of MMP-15 via FOXA1 in bladder cancer., PMID:33323547
Matrix metalloproteinase-7, -8, -9, -15, and -25 in minor salivary gland adenoid cystic carcinoma., PMID:33278774
Long noncoding RNA ZFAS1 silencing alleviates rheumatoid arthritis via blocking miR-296-5p-mediated down-regulation of MMP-15., PMID:33191176
Detection of genes responsible for cetuximab sensitization in colorectal cancer cells using CRISPR-Cas9., PMID:33048115
Remodeling the Skeletal Muscle Extracellular Matrix in Older Age-Effects of Acute Exercise Stimuli on Gene Expression., PMID:32992998
Silencing PROK2 Inhibits Invasion of Human Cervical Cancer Cells by Targeting MMP15 Expression., PMID:32887509
Matrix metalloproteinase 15 plays a pivotal role in human first trimester cytotrophoblast invasion and is not altered by maternal obesity., PMID:32614494
Effect of indole-3-carbinol on transcriptional profiling of wound-healing genes in macrophages of systemic lupus erythematosus patients: an RNA sequencing assay., PMID:32517571
The compendium of matrix metalloproteinase expression in the left ventricle of mice following myocardial infarction., PMID:32083973
Dominative role of MMP-14 over MMP-15 in human urinary bladder carcinoma on the basis of its enhanced specific activity., PMID:32049862
Generation of mmp15b Zebrafish Mutant to Investigate Liver Diseases., PMID:31993544
Role of Cyclosporine in Gingival Hyperplasia: An In Vitro Study on Gingival Fibroblasts., PMID:31963361
Inhibition of medaka ovulation by gap junction blockers due to its disrupting effect on the transcriptional process of LH-induced Mmp15 expression., PMID:31874135
SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis., PMID:31820782
Mayaro Virus Infects Human Chondrocytes and Induces the Expression of Arthritis-Related Genes Associated with Joint Degradation., PMID:31470617
Increased gene expression of inflammatory markers in nasal turbinate of patients with persistent allergic rhinitis and chronic obstruction., PMID:31363902
The oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression., PMID:31191014
LncRNA MAFG-AS1 promotes the aggressiveness of breast carcinoma through regulating miR-339-5p/MMP15., PMID:31002134
Nuclear Progestin Receptor Phosphorylation by Cdk9 Is Required for the Expression of Mmp15, a Protease Indispensable for Ovulation in Medaka., PMID:30836650
The prognostic value of matrix metalloproteinase-7 and matrix metalloproteinase-15 in acute myeloid leukemia., PMID:30809850
Plasminogen activator inhibitor 2 (PAI2) inhibits invasive potential of hepatocellular carcinoma cells in vitro via uPA- and RB/E2F1-related mechanisms., PMID:30600477
LncRNA MAFG-AS1 facilitates the migration and invasion of NSCLC cell via sponging miR-339-5p from MMP15., PMID:30599080
For research use only. Not for human or drug use.
