Catalog No.
YHE79601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp505
Predicted molecular weight
56.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P50995
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Annexin-11, Annexin A11, CAP-50, ANXA11, Annexin XI, ANX11, Calcyclin-associated annexin 50, 56 kDa autoantigen
ANXA11 Mutations in the FTD Spectrum: A Novel Finding in a Patient With Semantic Variant Primary Progressive Aphasia., PMID:40345169
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes., PMID:40118863
Semantic variant primary progressive aphasia with ANXA11 p.D40G., PMID:40042459
Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment., PMID:39755715
The RNA-Binding Properties of Annexins., PMID:39755246
Human TDP43 is required for ALS‑related annexin A11 toxicity in Drosophila., PMID:39301564
Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C., PMID:39260416
Non-canonical RNA-binding protein ANXA11 regulates microRNA resorting into small extracellular vesicles to mediate cisplatin resistance., PMID:39259536
Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C., PMID:38979278
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome., PMID:38923692
Annexin A11 aggregation in FTLD-TDP type C and related neurodegenerative disease proteinopathies., PMID:38896345
Clinical and genetic characteristics of 1672 cases of amyotrophic lateral sclerosis in China: a single-center retrospective study., PMID:38896262
Genetic and clinical landscape of Chinese frontotemporal dementia: dominance of TBK1 and OPTN mutations., PMID:38872230
Genetic Screening of Patients with Sporadic Alzheimer's Disease and Frontotemporal Lobar Degeneration in the Chinese Population., PMID:38701145
The structural properties of full-length annexin A11., PMID:38516187
Nationwide survey of patients with multisystem proteinopathy in Japan., PMID:38287512
Biomarkers of ocular allergy and dry eye disease., PMID:37876509
Pharmacovariome scanning using whole pharmacogene resequencing coupled with deep computational analysis and machine learning for clinical pharmacogenomics., PMID:37452347
Evaluation of genetic risk, its clinical manifestation and disease management based on 18 susceptibility gene markers among West-Slavonic patients with sarcoidosis., PMID:37336276
Generation of an Open-Access Patient-Derived iPSC Biobank for Amyotrophic Lateral Sclerosis Disease Modelling., PMID:37239468
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes., PMID:36993242
In Silico Exploration of Metabolically Active Peptides as Potential Therapeutic Agents against Amyotrophic Lateral Sclerosis., PMID:36982902
What Is in the Myopathy Literature?, PMID:36809200
Common pathophysiology for ANXA11 disorders caused by aspartate 40 variants., PMID:36651622
Integrative Proteomics and Transcriptomics Profiles of the Oviduct Reveal the Prolificacy-Related Candidate Biomarkers of Goats (Capra hircus) in Estrous Periods., PMID:36499219
Clinical and genetic characteristics of amyotrophic lateral sclerosis patients with ANXA11 variants., PMID:36458208
Urine proteomic signatures predicting the progression from premalignancy to malignant gastric cancer., PMID:36356476
Mutation spectrum of chinese amyotrophic lateral sclerosis patients with frontotemporal dementia., PMID:36345033
Genetic analysis of and clinical characteristics associated with ANXA11 variants in a Chinese cohort with amyotrophic lateral sclerosis., PMID:36280108
Adult-onset dominant muscular dystrophy in Greek families caused by Annexin A11., PMID:36134701
HSF1 Stimulates Glutamine Transport by Super-Enhancer-Driven lncRNA LINC00857 in Colorectal Cancer., PMID:36010849
CircSOD2 Contributes to Tumor Progression, Immune Evasion and Anti-PD-1 Resistance in Hepatocellular Carcinoma by Targeting miR-497-5p/ANXA11 Axis., PMID:36008700
Update on genetics of amyotrophic lateral sclerosis., PMID:35942673
A genome-wide association study on frequent exacerbation of asthma depending on smoking status., PMID:35606283
ANXA11 rs1049550 Associates with Löfgren's Syndrome and Chronic Sarcoidosis Patients., PMID:35563867
Re-analysis of the Hungarian amyotrophic lateral sclerosis population and evaluation of novel ALS genetic risk variants., PMID:35525134
Subcellular Proteome Analysis Reveals Apoptotic Vulnerability of T-Cell Acute Lymphoblastic Leukemia., PMID:35463978
Extracellular Matrix Derived From Dental Pulp Stem Cells Promotes Mineralization., PMID:35155398
Role of the IgG4-related cholangitis autoantigen annexin A11 in cholangiocyte protection., PMID:34718050
Analysis of the Expression and Prognostic Value of Annexin Family Proteins in Bladder Cancer., PMID:34484309
A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features., PMID:34099057
A Novel Multisystem Proteinopathy Caused by a Missense ANXA11 Variant., PMID:34048612
Genetic epidemiology of familial ALS in Brazil., PMID:33618928
Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11., PMID:33610019
Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis., PMID:33218681
ANXA11 mutations in ALS cause dysregulation of calcium homeostasis and stress granule dynamics., PMID:33087501
Association of TGF-β3 and ANXA11 with pulmonary sarcoidosis in Greek population., PMID:32552203
Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment., PMID:32344647
Inherited and Sporadic Amyotrophic Lateral Sclerosis and Fronto-Temporal Lobar Degenerations arising from Pathological Condensates of Phase Separating Proteins., PMID:31595953
For research use only. Not for human or drug use.
