Catalog No.
YHE74001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Tyr340
Predicted molecular weight
40.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49961
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen
Genetically predicted immune cells mediates the association between hepatocellular carcinoma and inflammatory proteins: a Mendelian randomization study., PMID:40504445
Expression of the Transcription Factor FOXP3 in Human Peripheral Blood B-Cell Subtypes (CD19+CD39+ and CD19+CD39-) and Evaluation of Their Regulatory Function., PMID:40497715
Increase of CD4+CD25+FoxP3+Regulatory T Cells in Myeloma., PMID:40497604
Immunoinflammatory evidence of rheumatoid arthritis caused by COVID-19., PMID:40495223
CD39-Diannexin alleviates the platelet storage lesion by protecting platelets from activation, a new attempt from a traditional perspective., PMID:40491155
Targeting CD39 boosts PD-1 blockade antitumor therapeutic efficacy via strengthening CD8 + TILs function and recruiting B cells in cervical cancer., PMID:40462160
Compromised adenosine-A2AR axis contributes to recurrent spontaneous abortion by promoting proinflammatory macrophage polarization., PMID:40373597
Characterization of the aryl hydrocarbon receptor as a potential candidate to improve cancer T cell therapies., PMID:40358739
Adenosine signaling in promoting the balance between erythropoiesis and myelopoiesis., PMID:40314242
Deconvoluting TCR-dependent and -independent activation is vital for reliable Ag-specific CD4+ T cell characterization by AIM assay., PMID:40279430
Regulatory T Cell Mimicry by a Subset of Mesenchymal GBM Stem Cells Suppresses CD4 and CD8 Cells., PMID:40277917
Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells., PMID:40274631
Immune-activated microspheres for enhanced chemoembolization of hepatocellular carcinoma by blocking the adenosine A2A receptor., PMID:40274057
PD1+ T Regulatory Cells Are Not Sufficient to Protect from Gestational Hypertension., PMID:40243452
Flow Cytometric Analysis of Mouse Brain CD8+ T Cell Activation., PMID:40220234
CD40L stimulates tumor-infiltrating B-cells and improves ex vivo TIL expansion., PMID:40199608
Adenosine-generating CD39+ plasmablasts predispose to successful infliximab therapy in pediatric IBD., PMID:40199584
Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39-dominant purinergic braking and downstream NLRP3 inflammasome., PMID:40192171
TGF-β Induces the Secretion of Extracellular Vesicles Enriched with CD39 and CD73 from Cervical Cancer Cells., PMID:40141056
Bacterial vaginosis associates with dysfunctional T cells and altered soluble immune factors in the cervicovaginal tract., PMID:40131862
Decreased circulating CD39+ regulatory T cell frequencies following non-traumatic brain death., PMID:40118258
Low levels of CD39+ Tregs may predict poor outcome in children with sepsis., PMID:40117807
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn's disease-like ileitis., PMID:40117343
CD73: a new immune checkpoint for leukemia treatment., PMID:40114928
mTOR Inhibition limits LPS induced acute kidney injury and ameliorates hallmarks of cellular senescence., PMID:40113898
The effects of nanocurcumin on immune-related factors in the ankylosing spondylitis patients: a double-blind, randomized, placebo-controlled clinical trial., PMID:40106064
Impact of Estrogen on Purinergic Signaling in Microvascular Disease., PMID:40076726
CD39 Contributes to the Ability of Cell Invasion in Heterogeneity of Colorectal Cancer., PMID:40052646
Knowledge about globin genetics for precision diagnosis of hemoglobinopathies: A case Study., PMID:40023305
Causal Association Between Inflammatory Proteins, Inflammatory Cells, and Cauda Equina Syndrome: A Two-Sample Mendelian Randomization., PMID:40020998
Relationship between purinergic signalling and oxidative stress in prostate cancer: Perspectives for future therapy., PMID:40015351
Predictive circulating biomarkers of the response to anti-PD-1 immunotherapy in advanced HER2 negative breast cancer., PMID:40000397
The CD39/CD73/Adenosine and NAD/CD38/CD203a/CD73 Axis in Cutaneous T-Cell Lymphomas., PMID:39996780
Adenosine metabolism and receptors in aging of the skin, musculoskeletal, immune and cardiovascular systems., PMID:39971100
Treg fitness signatures as a biomarker for disease activity in Juvenile Idiopathic Arthritis., PMID:39954509
Transvitreal Retinochoroidal Biopsies of Primary Uveal Melanoma Reveal an Association of Low HLA Class I and High NK Cell Abundance in Low-Risk Disease., PMID:39918475
Regulatory T cells converted from Th1 cells in tumors suppress cancer immunity via CD39., PMID:39907686
CD73 promotes the maturation of murine NK cells and their survival in the tumor microenvironment., PMID:39901844
Noncanonical NF-κB signaling in dendritic cells is required for ATP-driven indoleamine 2,3-dioxygenase 1 induction through P2Y11 receptor., PMID:39899472
T Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Bone Loss via CD39 and CD73-Mediated ATP Hydrolysis., PMID:39895982
Recirculating regulatory T cells mediate thymic regeneration through amphiregulin following damage., PMID:39892391
Blocking the CD39/CD73 pathway synergizes with anti-CD20 bispecific antibody in nodal B-cell lymphoma., PMID:39884778
Reduced autoimmunity associated with deletion of host CD73., PMID:39846845
Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39., PMID:39843911
OMIP-110: A 37-Color Spectral Flow Cytometric Panel to Assess Transcription Factors and Chemokine Receptors in Human Intestinal Lymphoid Cells., PMID:39838760
Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma., PMID:39791721
Elucidating the molecular association and potential mechanisms between psoriasis and atrial fibrillation through biomarker and immune infiltration analysis., PMID:39776247
Characterization of the adaptive immune response in a mouse model for HPV-positive head and neck squamous cell carcinoma with implications to human disease., PMID:39751916
Reduced number of regulatory T cells in maternal circulation precede idiopathic spontaneous preterm labor in a subset of patients., PMID:39743391
Assessment of adenosinergic activity of small extracellular vesicles in plasma of cancer patients and healthy donors., PMID:39704041
For research use only. Not for human or drug use.
