Catalog No.
YHE64801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asp369
Predicted molecular weight
43.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49366
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DHPS, Deoxyhypusine synthase, DHS, DS
Identification of phytochemicals in Nyctanthes arbor-tristis leaf: interpreting antidiabetic and antibacterial effect through in vitro and in silico analysis., PMID:40498355
High-fidelity in silico generation and augmentation of TCR repertoire data using generative adversarial networks., PMID:40419551
Yeast reconstituted translation assays for analysis of eIF5A function., PMID:40382135
Genetic analyses of Myc and hypusine circuits in tumorigenesis., PMID:40382132
An animal-type Na+/K+-ATPase, PhNKA2, is involved in the salt tolerance of the intertidal macroalga Pyropia haitanensis., PMID:40357162
Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel KCa3.1., PMID:40294255
Mapping dihydropteroate synthase evolvability through identification of a novel evolutionarily critical substructure., PMID:40254194
Disparate co-evolution and prevalence of sulfadoxine and pyrimethamine resistance alleles and haplotypes at dhfr and dhps genes across Africa., PMID:40247054
Prevalence of antimalaria drug resistance-conferring mutations associated with sulphadoxine-pyrimethamineine-resistant Plasmodium falciparum in East Africa: a systematic review and meta-analysis., PMID:40241183
Spermidine restricts neonatal inflammation via metabolic shaping of polymorphonuclear myeloid-derived suppressor cells., PMID:40166929
Biginelli dihydropyrimidines and their acetylated derivatives as L-/T-type calcium channel blockers: Synthesis, enantioseparation, and molecular modeling studies., PMID:40128864
Mirror substrates specificity of a 2, 3-dihydroxypropanesulfonate degrading enzyme in sulfate-reducing bacteria., PMID:40054810
In silico screening and molecular dynamics analysis of natural DHPS enzyme inhibitors targeting Acinetobacter baumannii., PMID:40044750
Development of a reliable, sensitive, and convenient assay for the discovery of new eIF5A hypusination inhibitors., PMID:39937781
Monitoring molecular markers associated with antimalarial drug resistance in south-east Senegal from 2021 to 2023., PMID:39846779
Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function., PMID:39832654
Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya., PMID:39819451
Combined transcriptome and whole genome sequencing analyses reveal candidate drug-resistance genes of Eimeria tenella., PMID:39811641
Synthesis of tetra-substituted thiophene derivatives as potential Hits combating antibiotic resistant bacteria ESKAPE., PMID:39809117
APE1-Activated and NIR-II Photothermal-Enhanced Chemodynamic Therapy Guided by Amplified Fluorescence Imaging., PMID:39808438
Maternal Exposure to Polystyrene Nanoplastics Disrupts Spermatogenesis in Mouse Offspring by Inducing Prdm14 Overexpression in Undifferentiated Spermatogonia., PMID:39791560
Knockout or inhibition of DHPS suppresses ovarian tumor growth and metastasis by attenuating the TGFβ pathway., PMID:39762448
A de novo Gene Promotes Seed Germination Under Drought Stress in Arabidopsis., PMID:39719058
Discovery of New Symmetrical and Asymmetrical 1,4-dihydropyridine Derivatives as Potential Antihypertensive Agents: An In silico Evaluation., PMID:39686637
Hypusination in intestinal epithelial cells protects mice from infectious colitis., PMID:39673545
Profile of molecular markers of Sulfadoxine-Pyrimethamine-resistant Plasmodium falciparum in individuals living in southern area of Brazzaville, Republic of Congo., PMID:39488015
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons., PMID:39469305
Synthesis of new 1,4-dihydropyridine derivative, anti-cancer, bacterial activity, molecular docking and adsorption, distribution, metabolism and excretion analysis., PMID:39440485
Co-based carbon material as CYP3A4-like nanozyme with both biocatalytic activity and inhibition behaviors., PMID:39406111
ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity., PMID:39392755
Novel Far-Red Fluorescent 1,4-Dihydropyridines for L-Type Calcium Channel Imaging., PMID:39388369
Design, In silico Screening, Synthesis, Characterisation and DFT-based Electronic Properties of Dihydropyridine-based Molecule as L-type Calcium Channel Blocker., PMID:39354859
Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons., PMID:39334388
Synthesis and characterization of new hexahydroquinoline derivatives and evaluation of their cytotoxicity, intracellular ROS production, and inhibitory effects on inflammatory mediators., PMID:39296790
Design and synthesis of ferrocenyl 1,4-dihydropyridines and their evaluation as kinesin-5 inhibitors., PMID:39291736
The Many Faces of Hypusinated eIF5A: Cell Context-Specific Effects of the Hypusine Circuit and Implications for Human Health., PMID:39125743
1,4-Dihydropyridine-based FA1 site-specific fluorescent probes for the selective detection and quantification of HSA levels in biofluids., PMID:39104182
Rational Design, Synthesis, and Computational Investigation of Dihydropyridine [2,3-d] Pyrimidines as Polyphenol Oxidase Inhibitors with Improved Potency., PMID:39097848
Evaluation of cilnidipine-loaded self-micro-emulsifying drug delivery system (SMEDDS) by quantification of comparative pharmacokinetic parameters using validated LC-ESI-MS/MS bioanalytical method and pharmacodynamic assessment., PMID:39089366
Synthesis, docking and characterization of some novel 5-(S-alkyl)-1.3.4-thiadiazole-2-carboxamide derivatives as anti-inflammatory and antibacterial agents., PMID:39068479
Design, Synthesis, and Biological Evaluation of 1,4-Dihydropyridine-Indole as a Potential Antidiabetic Agent via GLUT4 Translocation Stimulation., PMID:39013034
Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolism., PMID:38986570
DHPS-Mediated Hypusination Regulates METTL3 Self-m6A-Methylation Modification to Promote Melanoma Proliferation and the Development of Novel Inhibitors., PMID:38952061
Dihydropyrazine induces endoplasmic reticulum stress and inhibits autophagy in HepG2 human hepatoma cells., PMID:38945842
Optimization of diastereomeric dihydropyridines as antimalarials., PMID:38909569
An efficient sulfadiazine selection scheme for stable transformation in the model liverwort Marchantia polymorpha., PMID:38824404
18F-Labeled dihydropyridines via Hantzsch reaction for positron emission tomography of P-glycoprotein dysfunction., PMID:38823726
Plasmodium ovale spp dhfr mutations associated with reduced susceptibility to pyrimethamine in sub-Saharan Africa: a retrospective genetic epidemiology and functional study., PMID:38761813
Detection of novel Plasmodium falciparum coronin gene mutations in a recrudescent ACT-treated patient in South-Western Nigeria., PMID:38716192
For research use only. Not for human or drug use.
